[M::bwa_idx_load_from_disk] read 0 ALT contigs
[M::process] read 3497298 sequences (200000102 bp)...
[M::process] read 3551474 sequences (200000029 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17625, 491939, 16556, 17365)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (717, 2221, 4818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13020)
[M::mem_pestat] mean and std.dev: (3035.44, 2711.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17121)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 206, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (208.96, 98.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 713)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (888, 2440, 5056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13392)
[M::mem_pestat] mean and std.dev: (3198.82, 2731.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17560)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (785, 2317, 4882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13076)
[M::mem_pestat] mean and std.dev: (3109.86, 2730.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17173)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3497298 reads in 1162.441 CPU sec, 165.870 real sec
[M::process] read 3495858 sequences (200000108 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18845, 484139, 17423, 18420)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (708, 2215, 4745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12819)
[M::mem_pestat] mean and std.dev: (3026.07, 2720.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16856)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 208, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 579)
[M::mem_pestat] mean and std.dev: (211.01, 99.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 726)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (876, 2465, 5082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13494)
[M::mem_pestat] mean and std.dev: (3203.57, 2730.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (791, 2308, 4938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13232)
[M::mem_pestat] mean and std.dev: (3121.10, 2734.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17379)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3551474 reads in 977.978 CPU sec, 74.013 real sec
[M::process] read 3542046 sequences (200000034 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19487, 458476, 18549, 19384)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (769, 2297, 4923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13231)
[M::mem_pestat] mean and std.dev: (3105.09, 2727.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 217, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (220.50, 103.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 758)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (885, 2472, 5050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13380)
[M::mem_pestat] mean and std.dev: (3213.79, 2728.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17545)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (783, 2352, 4896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13122)
[M::mem_pestat] mean and std.dev: (3121.66, 2717.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17235)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3495858 reads in 929.683 CPU sec, 60.521 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19342, 474231, 18036, 18555)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (708, 2219, 4794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12966)
[M::mem_pestat] mean and std.dev: (3023.94, 2714.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 204, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (207.09, 97.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 712)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (855, 2411, 5052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13446)
[M::mem_pestat] mean and std.dev: (3195.71, 2756.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17643)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (768, 2295, 4900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13164)
[M::mem_pestat] mean and std.dev: (3094.77, 2725.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17296)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 3535164 sequences (200000111 bp)...
[M::mem_process_seqs] Processed 3542046 reads in 975.004 CPU sec, 70.040 real sec
[M::process] read 3494628 sequences (200000011 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20413, 447483, 19365, 20090)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (757, 2289, 4884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13138)
[M::mem_pestat] mean and std.dev: (3088.64, 2719.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 221, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (224.26, 105.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 769)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (920, 2469, 5046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13298)
[M::mem_pestat] mean and std.dev: (3217.29, 2724.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17424)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (816, 2383, 4907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13089)
[M::mem_pestat] mean and std.dev: (3140.72, 2709.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17180)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3535164 reads in 945.811 CPU sec, 63.944 real sec
[M::process] read 3552230 sequences (200000096 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19216, 460647, 18153, 19395)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (777, 2340, 4973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13365)
[M::mem_pestat] mean and std.dev: (3125.22, 2742.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17561)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 209, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 576)
[M::mem_pestat] mean and std.dev: (211.71, 98.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 721)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (918, 2458, 5095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13449)
[M::mem_pestat] mean and std.dev: (3227.85, 2753.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17626)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (817, 2355, 4981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13309)
[M::mem_pestat] mean and std.dev: (3149.70, 2730.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17473)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3494628 reads in 937.618 CPU sec, 59.609 real sec
[M::process] read 3495900 sequences (200000114 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20241, 455967, 18979, 19929)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (756, 2292, 4941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13311)
[M::mem_pestat] mean and std.dev: (3110.87, 2753.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 213, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 590)
[M::mem_pestat] mean and std.dev: (215.75, 100.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (916, 2472, 5047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13309)
[M::mem_pestat] mean and std.dev: (3222.84, 2742.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17440)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (803, 2362, 4982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13340)
[M::mem_pestat] mean and std.dev: (3153.70, 2741.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17519)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3552230 reads in 958.151 CPU sec, 62.980 real sec
[M::process] read 3521286 sequences (200000059 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19511, 458132, 18523, 18960)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (729, 2238, 4812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12978)
[M::mem_pestat] mean and std.dev: (3046.09, 2712.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 209, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 576)
[M::mem_pestat] mean and std.dev: (211.81, 99.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 721)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (881, 2491, 5036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13346)
[M::mem_pestat] mean and std.dev: (3205.39, 2723.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17501)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (817, 2368, 4992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13342)
[M::mem_pestat] mean and std.dev: (3156.67, 2741.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17517)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3495900 reads in 942.879 CPU sec, 62.788 real sec
[M::process] read 3487556 sequences (200000116 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19284, 468350, 18350, 19062)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (745, 2262, 4885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13165)
[M::mem_pestat] mean and std.dev: (3082.75, 2738.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17305)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 203, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (205.01, 95.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 696)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (893, 2430, 4953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13073)
[M::mem_pestat] mean and std.dev: (3175.85, 2706.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17133)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (766, 2259, 4859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13045)
[M::mem_pestat] mean and std.dev: (3080.29, 2720.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3521286 reads in 956.162 CPU sec, 62.192 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20314, 442409, 19060, 19941)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (771, 2313, 4890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13128)
[M::mem_pestat] mean and std.dev: (3099.80, 2722.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 217, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 600)
[M::mem_pestat] mean and std.dev: (220.39, 102.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 751)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (922, 2469, 5067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13357)
[M::mem_pestat] mean and std.dev: (3229.09, 2738.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17502)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (826, 2372, 4948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13192)
[M::mem_pestat] mean and std.dev: (3152.08, 2724.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17314)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 3511160 sequences (200000058 bp)...
[M::mem_process_seqs] Processed 3487556 reads in 925.975 CPU sec, 58.951 real sec
[M::process] read 3501844 sequences (200000099 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19452, 464761, 18160, 19438)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (736, 2241, 4809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12955)
[M::mem_pestat] mean and std.dev: (3056.56, 2723.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17028)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 202, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (204.37, 94.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 692)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (862, 2424, 4997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13267)
[M::mem_pestat] mean and std.dev: (3183.71, 2740.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17402)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (769, 2267, 4830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12952)
[M::mem_pestat] mean and std.dev: (3085.27, 2716.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3511160 reads in 938.040 CPU sec, 60.503 real sec
[M::process] read 3499432 sequences (200000114 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20898, 434717, 19543, 20491)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (788, 2373, 4975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13349)
[M::mem_pestat] mean and std.dev: (3142.62, 2726.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17536)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (226.20, 105.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 771)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (933, 2513, 5112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13470)
[M::mem_pestat] mean and std.dev: (3251.07, 2739.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17649)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (831, 2373, 4918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13092)
[M::mem_pestat] mean and std.dev: (3138.94, 2706.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17179)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3501844 reads in 928.500 CPU sec, 59.988 real sec
[M::process] read 3519340 sequences (200000058 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19595, 459630, 18587, 19408)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (760, 2322, 4922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13246)
[M::mem_pestat] mean and std.dev: (3119.76, 2745.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 206, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 560)
[M::mem_pestat] mean and std.dev: (208.22, 95.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (899, 2470, 5040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13322)
[M::mem_pestat] mean and std.dev: (3202.54, 2721.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17463)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (793, 2329, 4895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13099)
[M::mem_pestat] mean and std.dev: (3108.75, 2709.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17201)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3499432 reads in 938.969 CPU sec, 60.789 real sec
[M::process] read 3513754 sequences (200000042 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20241, 443355, 19239, 19952)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (782, 2324, 4915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13181)
[M::mem_pestat] mean and std.dev: (3113.72, 2724.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 216, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 596)
[M::mem_pestat] mean and std.dev: (218.91, 101.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 746)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (918, 2489, 5064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13356)
[M::mem_pestat] mean and std.dev: (3223.42, 2724.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17502)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (838, 2390, 4944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13156)
[M::mem_pestat] mean and std.dev: (3158.42, 2714.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17262)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3519340 reads in 928.275 CPU sec, 59.700 real sec
[M::process] read 3540674 sequences (200000004 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20984, 433697, 19765, 20241)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (813, 2377, 4935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13179)
[M::mem_pestat] mean and std.dev: (3141.19, 2717.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17301)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (224.97, 104.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 763)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (947, 2553, 5198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13700)
[M::mem_pestat] mean and std.dev: (3299.42, 2756.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17951)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (866, 2401, 5071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13481)
[M::mem_pestat] mean and std.dev: (3194.41, 2737.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17686)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3513754 reads in 934.167 CPU sec, 59.864 real sec
[M::process] read 3490038 sequences (200000024 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20198, 445595, 19503, 20226)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (795, 2303, 4887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13071)
[M::mem_pestat] mean and std.dev: (3109.06, 2721.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17163)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 214, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 586)
[M::mem_pestat] mean and std.dev: (216.74, 100.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 733)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (938, 2507, 5107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13445)
[M::mem_pestat] mean and std.dev: (3248.12, 2733.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17614)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (828, 2395, 4993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13323)
[M::mem_pestat] mean and std.dev: (3169.62, 2728.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3540674 reads in 953.202 CPU sec, 61.550 real sec
[M::process] read 3551008 sequences (200000008 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20915, 422682, 20154, 20711)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (803, 2336, 5002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13400)
[M::mem_pestat] mean and std.dev: (3143.26, 2731.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (231.85, 107.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (914, 2488, 5116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13520)
[M::mem_pestat] mean and std.dev: (3249.37, 2754.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17722)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (872, 2418, 4967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13157)
[M::mem_pestat] mean and std.dev: (3180.64, 2715.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17252)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3490038 reads in 915.279 CPU sec, 58.754 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20478, 445889, 19304, 19969)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (743, 2235, 4832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13010)
[M::mem_pestat] mean and std.dev: (3064.59, 2729.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 213, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 585)
[M::mem_pestat] mean and std.dev: (215.55, 100.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 732)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (946, 2505, 5052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13264)
[M::mem_pestat] mean and std.dev: (3238.13, 2725.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17370)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (820, 2409, 4986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13318)
[M::mem_pestat] mean and std.dev: (3165.67, 2718.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17484)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 3480612 sequences (200000051 bp)...
[M::mem_process_seqs] Processed 3551008 reads in 948.011 CPU sec, 61.372 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20920, 420200, 20174, 21065)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (844, 2439, 4990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13282)
[M::mem_pestat] mean and std.dev: (3177.99, 2723.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17428)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 3539572 sequences (200000017 bp)...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (232.38, 108.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (943, 2530, 5158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13588)
[M::mem_pestat] mean and std.dev: (3270.36, 2739.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17803)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (880, 2452, 5067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13441)
[M::mem_pestat] mean and std.dev: (3221.48, 2730.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17628)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_process_seqs] Processed 3480612 reads in 903.768 CPU sec, 57.532 real sec
[M::process] read 3496732 sequences (200000005 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20747, 441267, 19280, 20197)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (777, 2311, 4926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13224)
[M::mem_pestat] mean and std.dev: (3114.24, 2730.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17373)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 216, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 593)
[M::mem_pestat] mean and std.dev: (218.20, 101.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 742)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (936, 2504, 5094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13410)
[M::mem_pestat] mean and std.dev: (3250.98, 2732.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17568)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (817, 2370, 4998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13360)
[M::mem_pestat] mean and std.dev: (3157.01, 2723.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17541)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3539572 reads in 934.942 CPU sec, 60.421 real sec
[M::process] read 3505178 sequences (200000071 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21089, 426475, 20032, 20514)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (818, 2341, 4956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13232)
[M::mem_pestat] mean and std.dev: (3151.61, 2734.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17370)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (228.21, 106.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (951, 2525, 5122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13464)
[M::mem_pestat] mean and std.dev: (3263.50, 2742.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (880, 2487, 5093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13519)
[M::mem_pestat] mean and std.dev: (3227.98, 2721.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3496732 reads in 915.263 CPU sec, 58.759 real sec
[M::process] read 3496284 sequences (200000107 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19415, 462534, 18406, 19355)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (791, 2329, 4883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13067)
[M::mem_pestat] mean and std.dev: (3096.93, 2708.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17159)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 201, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (202.78, 91.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 677)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (924, 2525, 5096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13440)
[M::mem_pestat] mean and std.dev: (3254.80, 2729.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17612)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (819, 2405, 5001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13365)
[M::mem_pestat] mean and std.dev: (3173.45, 2740.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17547)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3505178 reads in 927.699 CPU sec, 59.171 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20804, 431042, 19471, 20529)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (807, 2421, 5029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13473)
[M::mem_pestat] mean and std.dev: (3177.85, 2742.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17695)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 608)
[M::mem_pestat] mean and std.dev: (223.32, 104.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (942, 2519, 5155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13581)
[M::mem_pestat] mean and std.dev: (3263.58, 2734.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17794)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (876, 2463, 5080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13488)
[M::mem_pestat] mean and std.dev: (3222.88, 2738.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 3501754 sequences (200000060 bp)...
[M::mem_process_seqs] Processed 3496284 reads in 917.440 CPU sec, 58.377 real sec
[M::process] read 3498480 sequences (200000091 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19576, 453525, 18752, 19399)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (771, 2334, 4941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13281)
[M::mem_pestat] mean and std.dev: (3111.16, 2722.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17451)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 206, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (208.55, 96.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (908, 2518, 5110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13514)
[M::mem_pestat] mean and std.dev: (3252.05, 2751.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17716)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (816, 2348, 4924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13140)
[M::mem_pestat] mean and std.dev: (3138.19, 2731.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3501754 reads in 945.344 CPU sec, 60.618 real sec
[M::process] read 3498666 sequences (200000047 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20550, 435262, 19546, 20399)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (823, 2381, 4991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13327)
[M::mem_pestat] mean and std.dev: (3170.57, 2751.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17495)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 217, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (219.79, 102.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 750)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (966, 2558, 5170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13578)
[M::mem_pestat] mean and std.dev: (3289.62, 2739.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17782)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (851, 2405, 5041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13421)
[M::mem_pestat] mean and std.dev: (3191.67, 2733.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17611)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3498480 reads in 917.225 CPU sec, 58.713 real sec
[M::process] read 3513530 sequences (200000069 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20322, 440672, 19446, 20218)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (823, 2430, 5066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13552)
[M::mem_pestat] mean and std.dev: (3194.69, 2745.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17795)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 214, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 586)
[M::mem_pestat] mean and std.dev: (216.38, 99.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 733)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (930, 2514, 5090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13410)
[M::mem_pestat] mean and std.dev: (3254.48, 2744.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17570)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (872, 2382, 5025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13331)
[M::mem_pestat] mean and std.dev: (3179.39, 2724.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17484)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3498666 reads in 923.944 CPU sec, 59.133 real sec
[M::process] read 3548728 sequences (200000044 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20573, 440676, 19598, 20348)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (795, 2327, 4945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13245)
[M::mem_pestat] mean and std.dev: (3129.34, 2733.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 215, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (217.46, 101.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 741)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (945, 2518, 5101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13413)
[M::mem_pestat] mean and std.dev: (3255.85, 2724.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17569)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (869, 2372, 5050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13412)
[M::mem_pestat] mean and std.dev: (3191.07, 2734.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3513530 reads in 931.089 CPU sec, 59.441 real sec
[M::process] read 3627964 sequences (200000045 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20707, 437064, 19368, 20328)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (843, 2408, 5003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13323)
[M::mem_pestat] mean and std.dev: (3181.41, 2735.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17483)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (222.49, 103.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (987, 2566, 5161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13509)
[M::mem_pestat] mean and std.dev: (3301.85, 2741.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17683)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (898, 2479, 5060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13384)
[M::mem_pestat] mean and std.dev: (3223.27, 2722.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17546)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3548728 reads in 940.566 CPU sec, 60.128 real sec
[M::process] read 3614180 sequences (200000082 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20127, 448167, 19147, 20041)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (800, 2381, 5008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13424)
[M::mem_pestat] mean and std.dev: (3162.69, 2743.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17632)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 213, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588)
[M::mem_pestat] mean and std.dev: (216.39, 101.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 736)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (968, 2568, 5137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13475)
[M::mem_pestat] mean and std.dev: (3272.65, 2724.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (873, 2452, 5072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13470)
[M::mem_pestat] mean and std.dev: (3227.88, 2743.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17669)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3627964 reads in 969.060 CPU sec, 62.628 real sec
[M::process] read 3595894 sequences (200000032 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20055, 453528, 18959, 19628)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (824, 2412, 4997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13343)
[M::mem_pestat] mean and std.dev: (3178.39, 2749.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17516)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 211, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (213.77, 98.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 723)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (947, 2566, 5192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13682)
[M::mem_pestat] mean and std.dev: (3292.45, 2750.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17927)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (876, 2475, 5058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13422)
[M::mem_pestat] mean and std.dev: (3219.07, 2731.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3614180 reads in 976.956 CPU sec, 65.616 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20668, 438092, 19524, 20244)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (814, 2358, 4964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13264)
[M::mem_pestat] mean and std.dev: (3150.58, 2728.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17414)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 217, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603)
[M::mem_pestat] mean and std.dev: (220.68, 102.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 755)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (965, 2568, 5230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13760)
[M::mem_pestat] mean and std.dev: (3302.80, 2745.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18025)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (901, 2474, 5081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13441)
[M::mem_pestat] mean and std.dev: (3223.64, 2718.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 3628766 sequences (200000115 bp)...
[M::mem_process_seqs] Processed 3595894 reads in 953.111 CPU sec, 61.035 real sec
[M::process] read 3570700 sequences (200000000 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20113, 453969, 18878, 20151)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (804, 2355, 4995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13377)
[M::mem_pestat] mean and std.dev: (3154.43, 2748.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 209, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 573)
[M::mem_pestat] mean and std.dev: (211.85, 98.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 717)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (943, 2514, 5127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13495)
[M::mem_pestat] mean and std.dev: (3266.97, 2739.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (865, 2402, 5031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13363)
[M::mem_pestat] mean and std.dev: (3189.33, 2727.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3628766 reads in 981.178 CPU sec, 63.684 real sec
[M::process] read 3593446 sequences (200000035 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20505, 441450, 19231, 20169)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (831, 2402, 5028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13422)
[M::mem_pestat] mean and std.dev: (3179.33, 2739.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17619)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 215, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (217.65, 100.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 741)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (985, 2558, 5164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13522)
[M::mem_pestat] mean and std.dev: (3296.60, 2741.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (888, 2486, 5027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13305)
[M::mem_pestat] mean and std.dev: (3216.32, 2716.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17444)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3570700 reads in 938.823 CPU sec, 59.937 real sec
[M::process] read 3554780 sequences (200000081 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19595, 458846, 18712, 19497)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (788, 2361, 4965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13319)
[M::mem_pestat] mean and std.dev: (3139.35, 2736.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 207, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 566)
[M::mem_pestat] mean and std.dev: (209.25, 96.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 708)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (975, 2573, 5171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13563)
[M::mem_pestat] mean and std.dev: (3302.50, 2731.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17759)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (866, 2468, 5071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13481)
[M::mem_pestat] mean and std.dev: (3208.65, 2725.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17686)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3593446 reads in 962.989 CPU sec, 61.569 real sec
[M::process] read 3599330 sequences (200000013 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20086, 448123, 19087, 19723)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (801, 2337, 4971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13311)
[M::mem_pestat] mean and std.dev: (3148.82, 2744.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17481)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 212, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 579)
[M::mem_pestat] mean and std.dev: (214.43, 98.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 724)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (981, 2584, 5186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13596)
[M::mem_pestat] mean and std.dev: (3314.47, 2735.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17801)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (875, 2430, 5023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13319)
[M::mem_pestat] mean and std.dev: (3202.55, 2729.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3554780 reads in 940.219 CPU sec, 59.904 real sec
[M::process] read 3574800 sequences (200000047 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20132, 448945, 18800, 20156)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (798, 2383, 4979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13341)
[M::mem_pestat] mean and std.dev: (3150.78, 2724.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17522)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 209, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 579)
[M::mem_pestat] mean and std.dev: (212.72, 99.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 725)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1011, 2643, 5207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13599)
[M::mem_pestat] mean and std.dev: (3344.16, 2744.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17795)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (887, 2444, 5007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13247)
[M::mem_pestat] mean and std.dev: (3190.83, 2697.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3599330 reads in 954.559 CPU sec, 61.519 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19862, 455230, 18622, 19478)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (794, 2351, 5002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13418)
[M::mem_pestat] mean and std.dev: (3152.92, 2752.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17626)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 208, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (209.45, 95.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 705)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (988, 2587, 5256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13792)
[M::mem_pestat] mean and std.dev: (3328.06, 2761.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18060)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (895, 2423, 5000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13210)
[M::mem_pestat] mean and std.dev: (3204.53, 2723.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 3593280 sequences (200000064 bp)...
[M::mem_process_seqs] Processed 3574800 reads in 949.939 CPU sec, 60.392 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20276, 438177, 19620, 20366)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (807, 2381, 4994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13368)
[M::mem_pestat] mean and std.dev: (3171.87, 2752.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 217, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (219.54, 102.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 750)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (984, 2568, 5225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13707)
[M::mem_pestat] mean and std.dev: (3312.26, 2755.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17948)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (858, 2417, 5033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13383)
[M::mem_pestat] mean and std.dev: (3200.44, 2740.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17558)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 3571732 sequences (200000038 bp)...
[M::mem_process_seqs] Processed 3593280 reads in 956.376 CPU sec, 61.759 real sec
[M::process] read 3588984 sequences (200000052 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20403, 442287, 19198, 20057)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (826, 2391, 5010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13378)
[M::mem_pestat] mean and std.dev: (3166.14, 2725.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17562)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 216, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 590)
[M::mem_pestat] mean and std.dev: (217.97, 100.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 738)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (969, 2559, 5161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13545)
[M::mem_pestat] mean and std.dev: (3285.97, 2737.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17737)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (886, 2474, 5090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13498)
[M::mem_pestat] mean and std.dev: (3233.04, 2735.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3571732 reads in 953.873 CPU sec, 61.395 real sec
[M::process] read 3582596 sequences (200000037 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20658, 434728, 20024, 20293)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (849, 2428, 5072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13518)
[M::mem_pestat] mean and std.dev: (3200.21, 2754.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17741)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (221.42, 102.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 756)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (995, 2616, 5259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13787)
[M::mem_pestat] mean and std.dev: (3339.68, 2757.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18051)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (886, 2462, 5109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13555)
[M::mem_pestat] mean and std.dev: (3231.51, 2727.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17778)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3588984 reads in 957.789 CPU sec, 61.047 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20206, 440277, 19399, 20118)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (832, 2398, 5016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13384)
[M::mem_pestat] mean and std.dev: (3173.57, 2733.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 215, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 590)
[M::mem_pestat] mean and std.dev: (217.86, 100.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 738)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (988, 2586, 5191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13597)
[M::mem_pestat] mean and std.dev: (3309.25, 2733.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17800)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (896, 2482, 5109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13535)
[M::mem_pestat] mean and std.dev: (3258.58, 2758.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17748)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 3568254 sequences (200000060 bp)...
[M::mem_process_seqs] Processed 3582596 reads in 948.741 CPU sec, 60.397 real sec
[M::process] read 3624040 sequences (200000005 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20843, 435321, 19268, 20249)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (867, 2468, 5089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13533)
[M::mem_pestat] mean and std.dev: (3225.54, 2750.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17755)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (221.03, 102.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 752)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1006, 2644, 5261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13771)
[M::mem_pestat] mean and std.dev: (3350.98, 2752.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18026)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (902, 2533, 5128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13580)
[M::mem_pestat] mean and std.dev: (3255.80, 2724.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17806)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3568254 reads in 937.829 CPU sec, 60.205 real sec
[M::process] read 3550146 sequences (200000009 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20750, 439162, 19223, 20203)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (833, 2424, 5045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13469)
[M::mem_pestat] mean and std.dev: (3187.50, 2743.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17681)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 216, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (219.21, 101.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 750)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (988, 2572, 5199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13621)
[M::mem_pestat] mean and std.dev: (3301.26, 2732.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17832)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (892, 2500, 5072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13432)
[M::mem_pestat] mean and std.dev: (3231.51, 2726.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17612)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3624040 reads in 968.331 CPU sec, 61.623 real sec
[M::process] read 3598506 sequences (200000053 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20349, 438268, 19308, 20001)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (857, 2450, 5007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13307)
[M::mem_pestat] mean and std.dev: (3192.78, 2723.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17457)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (218.46, 100.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (994, 2600, 5282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13858)
[M::mem_pestat] mean and std.dev: (3345.76, 2757.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18146)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (900, 2536, 5110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13530)
[M::mem_pestat] mean and std.dev: (3248.10, 2732.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17740)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3550146 reads in 941.304 CPU sec, 60.183 real sec
[M::process] read 3551326 sequences (200000033 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21016, 435169, 19945, 20485)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (821, 2425, 5069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13565)
[M::mem_pestat] mean and std.dev: (3200.21, 2752.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17813)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 217, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 600)
[M::mem_pestat] mean and std.dev: (219.94, 101.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 751)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1020, 2658, 5248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13704)
[M::mem_pestat] mean and std.dev: (3357.82, 2748.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17932)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (908, 2471, 5112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13520)
[M::mem_pestat] mean and std.dev: (3239.65, 2734.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17724)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3598506 reads in 948.458 CPU sec, 60.761 real sec
[M::process] read 3561922 sequences (200000022 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20056, 445572, 19050, 19768)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (856, 2413, 5026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13366)
[M::mem_pestat] mean and std.dev: (3196.63, 2734.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17536)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 210, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 574)
[M::mem_pestat] mean and std.dev: (212.31, 97.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 718)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1005, 2614, 5188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13554)
[M::mem_pestat] mean and std.dev: (3321.90, 2740.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17737)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (899, 2530, 5086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13460)
[M::mem_pestat] mean and std.dev: (3255.98, 2735.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3551326 reads in 939.787 CPU sec, 60.077 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20839, 431306, 19679, 20434)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (863, 2462, 5081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13517)
[M::mem_pestat] mean and std.dev: (3214.40, 2735.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 602)
[M::mem_pestat] mean and std.dev: (222.02, 102.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1020, 2641, 5277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13791)
[M::mem_pestat] mean and std.dev: (3360.42, 2754.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18048)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (922, 2532, 5107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13477)
[M::mem_pestat] mean and std.dev: (3270.70, 2739.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17662)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 3576320 sequences (200000071 bp)...
[M::mem_process_seqs] Processed 3561922 reads in 924.499 CPU sec, 58.785 real sec
[M::process] read 1764368 sequences (98807667 bp)...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20074, 445552, 18949, 19735)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (840, 2432, 5042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13446)
[M::mem_pestat] mean and std.dev: (3189.47, 2733.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17648)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 212, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 581)
[M::mem_pestat] mean and std.dev: (213.98, 98.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 727)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1006, 2613, 5196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13576)
[M::mem_pestat] mean and std.dev: (3329.13, 2749.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17766)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (930, 2555, 5161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13623)
[M::mem_pestat] mean and std.dev: (3280.70, 2736.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17854)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 3576320 reads in 946.146 CPU sec, 60.783 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10467, 209341, 9787, 10414)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (872, 2477, 5058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13430)
[M::mem_pestat] mean and std.dev: (3225.07, 2737.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17616)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (226.44, 104.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 772)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1026, 2649, 5276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13776)
[M::mem_pestat] mean and std.dev: (3364.42, 2746.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18026)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (961, 2604, 5274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13900)
[M::mem_pestat] mean and std.dev: (3341.54, 2777.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18213)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 1764368 reads in 468.706 CPU sec, 30.290 real sec
[main] Version: 0.7.17-r1188
[main] CMD: bwa mem -SP5M -t 20 /oak/stanford/groups/akundaje/marinovg/genomes/Phaeophyta/Desmarestia-herbacea_MALE/bwa-indexes/Desmarestia-herbacea_MALE.fa /oak/stanford/groups/akundaje/marinovg/papers/2024_ToL_Hi-C/2023-07-09/13-brown-algae/juicer-Desmarestia_herbacea_gametophyte_male-SRX23262818/splits/Desmarestia_herbacea_gametophyte_male-SRX23262818_R1.fastq.gz /oak/stanford/groups/akundaje/marinovg/papers/2024_ToL_Hi-C/2023-07-09/13-brown-algae/juicer-Desmarestia_herbacea_gametophyte_male-SRX23262818/splits/Desmarestia_herbacea_gametophyte_male-SRX23262818_R2.fastq.gz
[main] Real time: 3079.946 sec; CPU: 45981.942 sec
Picked up _JAVA_OPTIONS: -Xmx16384m
Picked up _JAVA_OPTIONS: -Xmx16384m
Picked up _JAVA_OPTIONS: -Xmx16384m
Picked up _JAVA_OPTIONS: -Xmx16384m