# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	92	4.242334e-41	6.067920989782608e-39	2.083554	416	0.01133237	534	0.00045089042434456926	1.196361	108	118	0.007518274	
GO Biological Process	purine ribonucleoside monophosphate biosynthetic process	167	8.853623e-27	6.97633682976048e-25	2.096056	261	0.007109973	710	0.0046251642409859154	1.225439	60	64	0.004176819	
GO Biological Process	mRNA cleavage	549	1.297673e-11	3.1103969047358836e-10	2.115687	101	0.002751369	973	0.028440548052415214	1.307135	23	23	0.001601114	
GO Biological Process	snRNA processing	628	1.551824e-10	3.2516643337579617e-9	2.359825	71	0.001934131	973	0.028440548052415214	1.307135	23	23	0.001601114	
GO Biological Process	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	667	5.051042e-10	9.965016743328336e-9	2.012426	96	0.002615162	928	0.02274731669396552	1.267525	32	33	0.002227637	
GO Cellular Component	mitochondrial ribosome	65	9.30319e-22	2.47321728e-20	2.004712	233	0.006347217	101	0.00004537218154455445	1.245623	81	85	0.005638705	
GO Cellular Component	endoribonuclease complex	116	6.801385e-12	1.0131718344827586e-10	2.02876	115	0.003132747	163	0.004458326930061349	1.307135	29	29	0.002018796	
GO Cellular Component	precatalytic spliceosome	123	2.123491e-11	2.983245892682927e-10	2.193189	91	0.002478956	167	0.005690663051497007	1.307135	28	28	0.001949182	
GO Cellular Component	COPI-coated vesicle	133	1.305113e-10	1.695665612030075e-9	2.050442	98	0.002669645	206	0.017640237669902914	1.307135	23	23	0.001601114	
GO Cellular Component	mitochondrial small ribosomal subunit	154	1.581744e-9	1.774840020779221e-8	2.052493	86	0.00234275	228	0.04008097515789474	1.260452	27	28	0.001879568	
GO Molecular Function	rRNA binding	24	3.879054e-27	6.823902495e-25	2.501599	182	0.004957912	142	0.01694811890140845	1.219993	56	60	0.003898364	
GO Molecular Function	RNA polymerase II repressing transcription factor binding	30	2.561288e-22	3.6045859786666663e-20	2.102307	213	0.005802392	136	0.013055547797058822	1.307135	29	29	0.002018796	
GO Molecular Function	NF-kappaB binding	41	3.090343e-20	3.182299547804878e-18	2.333557	152	0.004140674	140	0.016585394181428573	1.307135	28	28	0.001949182	
GO Molecular Function	snRNA binding	111	1.336461e-11	5.083367875675676e-10	2.064337	107	0.002914817	137	0.014704890089051095	1.272737	37	38	0.002575705	
Mouse Phenotype Single KO	abnormal cellular replicative senescence	15	7.440427e-29	4.5421326692666665e-26	2.082685	287	0.007818246	138	0.000006761376183333334	1.307135	60	60	0.004176819	
Mouse Phenotype Single KO	early cellular replicative senescence	25	8.626007e-23	3.15953384396e-20	2.007951	244	0.006646871	176	0.00004551254283011364	1.307135	52	52	0.00361991