# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	negative regulation of gene expression, epigenetic	1	2.156636e-72	2.8379173124e-68	6.438582	157	0.03486565	185	0.00034249178254054056	1.804744	49	114	0.01095707	
GO Biological Process	regulation of gene expression, epigenetic	2	9.466935e-67	6.22876988325e-63	3.668217	253	0.05618477	108	1.1806721457129632e-7	1.726923	102	248	0.02280859	
GO Biological Process	chromatin silencing	7	6.238994e-43	1.1728417435142858e-39	6.034059	97	0.02154119	203	0.0011661142793103448	1.818034	42	97	0.009391771	
GO Biological Process	chromatin assembly or disassembly	9	9.724245e-42	1.4217926661666667e-38	3.415083	172	0.03819676	128	0.0000047860393290625	1.769154	75	178	0.01677102	
GO Biological Process	nucleosome organization	13	3.761848e-41	3.8078582947692313e-38	3.486212	165	0.03664224	120	0.0000016221274753333332	1.817021	74	171	0.01654741	
GO Biological Process	chromatin assembly	15	1.116626e-38	9.795787689333333e-36	3.482475	155	0.0344215	124	0.0000030576942186290325	1.83365	69	158	0.01542934	
GO Biological Process	negative regulation of megakaryocyte differentiation	16	1.484094e-38	1.220574559125e-35	36.94874	32	0.007106374	287	0.03660906243275261	2.565929	11	18	0.00245975	
GO Biological Process	nucleosome assembly	22	5.314148e-35	3.1785851605454546e-32	3.496933	139	0.03086831	129	0.000005668969625503876	1.862845	63	142	0.01408766	
GO Biological Process	gene silencing	23	6.16154e-35	3.525204559130435e-32	3.314099	149	0.03308905	154	0.00003659593094285714	1.702844	73	180	0.01632379	
GO Biological Process	positive regulation of gene expression, epigenetic	25	1.074644e-33	5.6564961583999995e-31	5.145804	87	0.01932045	231	0.009674770233766235	1.784487	34	80	0.007602862	
GO Biological Process	DNA packaging	29	1.95711e-32	8.88055534137931e-30	2.916676	166	0.03686431	178	0.00013869903885955055	1.624658	77	199	0.01721825	
GO Biological Process	protein-DNA complex subunit organization	34	1.524663e-31	5.900894240294118e-29	2.540079	203	0.04508106	163	0.000053914513908588955	1.578746	94	250	0.02101968	
GO Biological Process	ncRNA metabolic process	36	4.827993e-31	1.7647655524166666e-28	2.110176	290	0.06440151	74	9.88350617608108e-10	1.535775	203	555	0.04539356	
GO Biological Process	DNA conformation change	37	1.129762e-29	4.017983285945946e-27	2.42234	208	0.04619143	168	0.00006394953641011905	1.539059	103	281	0.0230322	
GO Biological Process	ncRNA processing	39	2.385539e-29	8.049053256666666e-27	2.323745	223	0.04952254	84	3.6008569578571423e-9	1.622261	153	396	0.03421288	
GO Biological Process	viral gene expression	40	4.093656e-29	1.3467104826000002e-26	3.808794	103	0.02287364	90	1.0057711735888889e-8	2.115927	64	127	0.01431127	
GO Biological Process	viral transcription	42	1.28786e-28	4.034988033333333e-26	3.910828	98	0.02176327	82	2.6317743239024393e-9	2.229447	60	113	0.01341682	
GO Biological Process	chromatin silencing at rDNA	43	6.109856e-28	1.8697580256744185e-25	10.24275	42	0.009327115	230	0.009255937616521739	2.216029	19	36	0.004248658	
GO Biological Process	ribosome biogenesis	45	6.808744e-27	1.991028051022222e-24	2.37513	195	0.04330446	99	4.08415883e-8	1.650918	127	323	0.02839893	
GO Biological Process	protein-DNA complex assembly	47	5.000089e-26	1.3999185351276595e-23	2.476468	174	0.03864091	190	0.0005474389865526316	1.552978	81	219	0.0181127	
GO Cellular Component	nucleosome	8	5.356362e-64	1.156974192e-61	7.668804	121	0.02687097	28	9.937882285714286e-10	2.279344	57	105	0.01274597	
GO Cellular Component	DNA packaging complex	14	5.084659e-57	6.2759219657142864e-55	6.380746	124	0.0275372	29	2.207781583448276e-9	2.211864	59	112	0.0131932	
GO Cellular Component	protein-DNA complex	18	3.373696e-38	3.23874816e-36	3.167852	174	0.03864091	27	7.472249600000001e-11	1.953894	94	202	0.02101968	
GO Cellular Component	chromatin	19	4.656266e-37	4.234751393684211e-35	2.051478	370	0.08216744	21	8.88912e-14	1.676061	194	486	0.04338104	
GO Cellular Component	nuclear nucleosome	23	6.941725e-31	5.215348173913043e-29	10.49296	46	0.01021541	52	0.0027108751015384614	2.204366	21	40	0.004695886	
GO Cellular Component	ribosomal subunit	32	4.382809e-21	2.3667168599999997e-19	2.820737	111	0.02465023	36	1.9579185600000002e-7	1.815694	80	185	0.01788909	
GO Cellular Component	PML body	33	8.193809e-20	4.29057634909091e-18	2.905832	99	0.02198534	69	0.013303869495652175	1.644888	38	97	0.008497317	
GO Cellular Component	ribosome	38	2.994529e-17	1.3617226610526316e-15	2.30392	129	0.02864757	35	1.2732689005714286e-7	1.725775	97	236	0.02169052	
GO Cellular Component	cytosolic ribosome	41	2.620213e-15	1.1043239180487806e-13	2.721031	83	0.01843216	31	7.383966967741936e-9	2.174375	58	112	0.01296959	
GO Cellular Component	large ribosomal subunit	42	9.189962e-15	3.7810129371428574e-13	2.949209	70	0.01554519	43	0.0002598079345116279	1.789051	49	115	0.01095707	
GO Cellular Component	chromosome, telomeric region	43	1.267832e-14	5.094915572093023e-13	2.480231	93	0.0206529	62	0.007759492025806452	1.508548	60	167	0.01341682	
GO Cellular Component	nuclear chromosome, telomeric region	44	1.326886e-14	5.2110432e-13	2.715957	79	0.01754386	74	0.018585620756756755	1.526834	48	132	0.01073345	
GO Cellular Component	cytosolic large ribosomal subunit	49	2.477473e-13	8.736884375510205e-12	3.392777	51	0.01132578	39	0.000003651113353846154	2.340311	34	61	0.007602862	
GO Cellular Component	ficolin-1-rich granule lumen	52	6.555452e-11	2.178427126153846e-9	2.334277	75	0.01665556	54	0.0047900928	1.625339	48	124	0.01073345	
GO Cellular Component	small ribosomal subunit	64	1.137582e-7	0.0000030714714	2.565887	41	0.009105041	60	0.007038144	1.807813	31	72	0.006932021	
GO Cellular Component	PRC1 complex	65	1.378208e-7	0.0000036639129599999998	6.733976	13	0.002886964	79	0.043373478075949365	2.799195	8	12	0.001788909	
GO Cellular Component	cytosolic small ribosomal subunit	79	0.000001258995	0.0000275385235443038	2.76281	30	0.006662225	53	0.00466339598490566	2.099396	22	44	0.004919499	
GO Cellular Component	mitochondrial nucleoid	111	0.00008188933	0.0012748176778378379	2.459588	24	0.00532978	71	0.015624369126760561	1.999425	20	42	0.004472272	
GO Molecular Function	nucleosome binding	8	2.209364e-23	1.165991851e-20	3.912955	79	0.01754386	35	0.00012074521925714285	2.163014	34	66	0.007602862	
GO Molecular Function	structural constituent of ribosome	9	1.544677e-19	7.246251437777778e-17	2.824665	102	0.02265157	19	2.2571878610526316e-8	1.969804	76	162	0.01699463	
GO Molecular Function	nucleosomal DNA binding	10	2.130875e-17	8.996554250000001e-15	4.260973	52	0.01154786	56	0.024381258375	2.008118	22	46	0.004919499	
GO Molecular Function	chromatin DNA binding	11	2.56137e-14	9.831003763636364e-12	2.492438	90	0.01998668	43	0.0009207075443255815	1.816785	45	104	0.01006261	
GO Molecular Function	rRNA binding	12	8.98164e-14	3.16004034e-11	4.37	39	0.008660893	53	0.020141505064150945	1.889457	27	60	0.006037567	
GO Molecular Function	peptidyl-prolyl cis-trans isomerase activity	16	5.557771e-10	1.466556822625e-7	2.97871	44	0.009771264	34	0.0000991938410882353	2.499281	25	42	0.00559034	
GO Molecular Function	cis-trans isomerase activity	17	1.393217e-9	3.4600953964705877e-7	2.887576	44	0.009771264	39	0.0002864939861025641	2.385678	25	44	0.00559034	
Human Phenotype	Abnormality of iron homeostasis	7	5.625855e-10	5.363047202142857e-7	5.09877	23	0.005107706	35	0.011547405337714286	2.624245	15	24	0.003354204	
Human Phenotype	Abnormality of transition element cation homeostasis	8	5.897669e-10	4.919393154625e-7	4.86898	24	0.00532978	55	0.03300668416545454	2.316575	16	29	0.003577818	
Human Phenotype	Developmental stagnation	24	0.000003917949	0.001089353069875	7.700053	9	0.001998668	56	0.03269214711071428	3.673943	7	8	0.001565295	
Human Phenotype	Urinary bladder sphincter dysfunction	63	0.0002604988	0.027592198292063493	3.097263	14	0.003109038	46	0.025827237226086954	2.88667	11	16	0.00245975	
Mouse Phenotype Single KO	abnormal induced cell death	4	2.521066e-18	5.7713503405e-15	2.161033	158	0.03508772	44	0.008833641356363638	1.512361	76	211	0.01699463	
Mouse Phenotype	abnormal conotruncus septation	12	3.752092e-12	2.9894793010000002e-9	6.615484	23	0.005107706	202	0.04801131880693069	3.598965	6	7	0.001341682	
Mouse Phenotype	increased hemoglobin concentration distribution width	20	1.192759e-8	0.0000057019843995	5.900064	17	0.003775261	202	0.04801131880693069	3.598965	6	7	0.001341682