# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	53	3.742391e-16	9.29172135264151e-14	3.243999	67	0.02240053	204	0.0017100765549019608	1.916937	38	113	0.01153613	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	54	6.828831e-16	1.6640849468333333e-13	3.565295	58	0.01939151	92	0.0000013027417151630433	2.270484	47	118	0.01426837	
GO Biological Process	ncRNA processing	56	5.22234e-15	1.2271566439285715e-12	2.102199	134	0.04480107	166	0.0006107208428493976	1.497065	104	396	0.03157256	
GO Biological Process	regulation of DNA-templated transcription in response to stress	58	1.180009e-14	2.677196281206897e-12	2.953436	69	0.02306921	184	0.0011925265082065217	1.916089	40	119	0.01214329	
GO Biological Process	protein folding	67	2.350397e-12	4.616249869104478e-10	2.225979	95	0.03176195	304	0.019145834223026317	1.513371	60	226	0.01821494	
GO Biological Process	nuclear-transcribed mRNA catabolic process	69	3.37445e-12	6.435418485507247e-10	2.420216	79	0.02641257	115	0.00007685842352869564	1.813752	63	198	0.01912568	
GO Biological Process	ribosome biogenesis	70	3.671853e-12	6.902559089571428e-10	2.053791	112	0.03744567	168	0.0006459082617619048	1.55304	88	323	0.02671524	
GO Biological Process	rRNA metabolic process	71	4.901234e-12	9.083850451549296e-10	2.251617	90	0.03009027	202	0.0016680980292574255	1.584657	72	259	0.02185792	
GO Biological Process	rRNA processing	72	5.255446e-12	9.605057488055557e-10	2.272745	88	0.0294216	211	0.0021093290769668245	1.583435	70	252	0.02125076	
GO Biological Process	translational elongation	79	3.206381e-11	5.34085665556962e-9	3.0312	49	0.01638248	194	0.001433428862371134	1.934052	38	112	0.01153613	
GO Biological Process	viral gene expression	80	4.105841e-11	6.753595214875e-9	2.894937	52	0.01738549	110	0.000044172370454545454	2.064699	46	127	0.01396478	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to hypoxia	84	5.753272e-11	9.012774553333334e-9	3.154779	45	0.01504514	397	0.04369808899748111	1.82704	25	78	0.007589557	
GO Biological Process	mRNA catabolic process	85	6.550024e-11	1.0140207743058824e-8	2.243935	81	0.02708124	135	0.00022353086078518518	1.739548	65	213	0.01973285	
GO Biological Process	viral transcription	86	8.470781e-11	1.2961279904534883e-8	2.943908	49	0.01638248	102	0.000023165129401960785	2.169165	43	113	0.01305404	
GO Biological Process	regulation of signal transduction by p53 class mediator	89	1.527741e-10	2.258825148202247e-8	2.190579	82	0.02741558	134	0.00022016627324626868	1.824117	56	175	0.01700061	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	90	1.905558e-10	2.7861375246666662e-8	3.236908	41	0.01370779	139	0.00023081255209352517	2.168617	35	92	0.01062538	
GO Biological Process	mitochondrial translational termination	92	2.348189e-10	3.3586759838043473e-8	3.396007	38	0.01270478	216	0.002476118673379629	2.031164	31	87	0.00941105	
GO Biological Process	cotranslational protein targeting to membrane	95	3.887473e-10	5.3847639165263157e-8	3.105482	42	0.01404213	125	0.000165955728584	2.152178	37	98	0.01123254	
GO Biological Process	protein localization to endoplasmic reticulum	98	7.373176e-10	9.900369692244898e-8	2.65911	52	0.01738549	169	0.0006521401068402367	1.930769	42	124	0.01275046	
GO Biological Process	regulation of intrinsic apoptotic signaling pathway	99	1.004853e-9	1.3356424875757575e-7	2.256277	70	0.02340354	377	0.036565789403183016	1.581391	43	155	0.01305404	
GO Cellular Component	ribosomal subunit	20	4.016836e-16	3.470546304e-14	2.945886	77	0.0257439	28	0.0000010347220799999999	1.972018	64	185	0.01942927	
GO Cellular Component	ribosome	21	1.70883e-14	1.4061229714285713e-12	2.473723	92	0.03075894	25	3.540163968e-7	1.884019	78	236	0.02367942	
GO Cellular Component	mitochondrial ribosome	27	3.485273e-11	2.2305747199999996e-9	3.801497	36	0.01203611	51	0.005820490164705883	1.94483	29	85	0.008803886	
GO Cellular Component	large ribosomal subunit	28	4.136125e-10	2.55258e-8	2.917769	46	0.01537947	46	0.0036606793460869564	1.83403	37	115	0.01123254	
GO Cellular Component	cytosolic part	29	9.544e-10	5.6869075862068965e-8	2.014364	91	0.03042461	38	0.0005109500463157896	1.638855	69	240	0.02094718	
GO Cellular Component	cytosolic ribosome	31	1.596419e-8	8.898748490322582e-7	2.467806	50	0.01671682	35	0.00015405386605714288	2.035844	40	112	0.01214329	
GO Cellular Component	small ribosomal subunit	35	2.628534e-7	0.000012977447862857143	2.920794	31	0.01036443	41	0.0018949092058536585	2.137637	27	72	0.008196721	
GO Cellular Component	transcriptional repressor complex	41	0.000001903096	0.00008020853385365853	2.011032	55	0.0183885	29	0.000002169571332413793	2.472447	36	83	0.01092896	
GO Cellular Component	SWI/SNF superfamily-type complex	49	0.000007066406	0.0002491989707755102	2.239374	38	0.01270478	34	0.0000702677985882353	2.375152	30	72	0.009107468	
GO Cellular Component	methyltransferase complex	53	0.00001085478	0.00035390678943396223	2.195541	38	0.01270478	48	0.0038743019999999996	1.941882	31	91	0.00941105	
GO Cellular Component	nuclear transcriptional repressor complex	62	0.00003224821	0.0008987888206451613	2.830427	21	0.007021063	49	0.004922119836734694	2.7519	14	29	0.004250152	
GO Cellular Component	INO80-type complex	70	0.00004789973	0.001182439049142857	4.52234	11	0.0036777	57	0.02446350517894737	2.726261	11	23	0.003339405	
GO Cellular Component	Ino80 complex	71	0.00004793825	0.0011667224788732393	5.578408	9	0.003009027	54	0.0173264128	3.206455	9	16	0.00273224	
GO Cellular Component	histone methyltransferase complex	75	0.00006342188	0.0014612401151999999	2.169924	32	0.01069876	44	0.0022064077963636366	2.147963	26	69	0.007893139	
GO Cellular Component	90S preribosome	81	0.0001078041	0.0022998208	2.949169	17	0.005683718	61	0.03632516616393443	2.390475	13	31	0.00394657	
GO Cellular Component	cytosolic small ribosomal subunit	88	0.0001840389	0.003613854763636364	2.634322	19	0.006352391	56	0.023272938514285715	2.202413	17	44	0.005160899	
GO Cellular Component	mitotic spindle midzone	95	0.0004073746	0.007409929566315789	3.109874	13	0.004346372	66	0.046157053090909096	3.325213	7	12	0.002125076	
GO Molecular Function	structural constituent of ribosome	9	2.724943e-12	1.2783010384444444e-9	2.709978	65	0.02173186	25	0.000008606886448800001	2.005684	57	162	0.01730419	
GO Molecular Function	repressing transcription factor binding	32	0.000008575622	0.001131446127625	2.042679	46	0.01537947	55	0.02473435670909091	2.090134	22	60	0.00667881	
GO Molecular Function	histone methyltransferase activity	57	0.00005647227	0.004182910946315789	2.074735	36	0.01203611	43	0.002443076991627907	2.318792	24	59	0.007285974	
GO Molecular Function	SNAP receptor activity	108	0.0008415799	0.03289954016481481	2.261673	20	0.006686727	53	0.02254587830188679	2.363566	17	41	0.005160899	
Human Phenotype	Lipomatous tumor	35	0.00001607319	0.0030644684819999997	4.674372	12	0.004012036	156	0.04173673619935898	3.257351	8	14	0.002428658	
Human Phenotype	Abnormality of reticulocytes	37	0.00001981835	0.0035742662040540536	3.25456	18	0.006018054	143	0.034152012686713286	2.418336	14	33	0.004250152	
Human Phenotype	Abnormality of the pylorus	41	0.00003486796	0.005674973099512196	2.393452	28	0.009361418	148	0.03992717409459459	2.470158	13	30	0.00394657	
Human Phenotype	Abnormality of adipose tissue	57	0.0000932558	0.010917472866666666	2.219581	29	0.009695754	162	0.0464405787345679	2.000128	20	57	0.006071645	
Mouse Phenotype Single KO	abnormal heart ventricle wall thickness	1	1.995602e-11	1.8273727514e-7	2.168695	92	0.03075894	36	0.006181002979722221	1.842975	43	133	0.01305404	
Mouse Phenotype Single KO	thin ventricular wall	10	4.259516e-8	0.000039004388012	2.072551	68	0.02273487	67	0.018310801883582088	1.900121	32	96	0.009714633	
Mouse Phenotype Single KO	abnormal fetal cardiomyocyte morphology	61	0.0002013107	0.03021970622786885	2.360231	23	0.007689736	92	0.044639250281521735	2.736175	12	25	0.003642987	
Mouse Phenotype	abnormal cellular replicative senescence	1	6.126223e-13	5.8572818103e-9	3.17084	54	0.01805416	77	0.002279434284935065	2.103706	31	84	0.00941105	
Mouse Phenotype	early cellular replicative senescence	2	9.744316e-12	4.6582702638000004e-8	3.185556	48	0.01604814	101	0.005635034727623763	2.108354	27	73	0.008196721	
Mouse Phenotype	abnormal KLRG1-positive NK cell number	41	0.00002093872	0.004882807363902439	3.119521	19	0.006352391	195	0.026285522864615385	3.000192	10	19	0.003035823	
Mouse Phenotype	small ureteric bud	111	0.0004585455	0.039496878608108105	4.100633	9	0.003009027	239	0.03783052875439331	5.700364	4	4	0.001214329