# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	DNA replication-dependent nucleosome assembly	6	9.374061e-35	2.05588781165e-31	19.91724	37	0.007956989	241	0.003757555180082988	2.388526	18	32	0.004070556	
GO Biological Process	nucleosome organization	7	1.161442e-31	2.1833450397142857e-28	3.069094	150	0.03225806	54	5.267162677407408e-9	1.986558	80	171	0.01809136	
GO Biological Process	negative regulation of gene expression, epigenetic	8	6.83553e-31	1.124359240875e-27	4.05079	102	0.02193548	130	0.00005102831435846154	1.899647	51	114	0.01153324	
GO Biological Process	regulation of gene expression, epigenetic	9	2.239033e-30	3.273715027444444e-27	2.611539	186	0.04	112	0.000006981668412767857	1.643717	96	248	0.02170963	
GO Biological Process	chromatin assembly or disassembly	11	1.847486e-28	2.2100971158181816e-25	2.864891	149	0.03204301	63	5.267042227301588e-8	1.908435	80	178	0.01809136	
GO Biological Process	chromatin assembly	13	2.267233e-27	2.2949630036153847e-24	2.958995	136	0.02924731	65	6.617086152923077e-8	1.961884	73	158	0.01650837	
GO Biological Process	nucleosome assembly	14	7.950647e-27	7.473040276642857e-24	3.069673	126	0.02709677	68	1.102658211485294e-7	2.003521	67	142	0.01515152	
GO Biological Process	DNA conformation change	15	8.838348e-27	7.753588088799998e-24	2.31193	205	0.04408602	119	0.000013355655173109243	1.586684	105	281	0.02374491	
GO Biological Process	chromatin silencing at rDNA	17	2.0844e-26	1.6134482117647057e-23	9.68278	41	0.008817204	269	0.006746922592936803	2.241086	19	36	0.004296698	
GO Biological Process	negative regulation of megakaryocyte differentiation	19	4.433908e-26	3.070831335368421e-23	26.83551	24	0.00516129	362	0.026200855819337017	2.594942	11	18	0.002487562	
GO Biological Process	protein-DNA complex subunit organization	20	1.835822e-25	1.2078790849e-22	2.326491	192	0.04129032	73	1.5358966685068492e-7	1.732478	102	250	0.02306649	
GO Biological Process	ncRNA processing	27	6.366572e-22	3.10287855362963e-19	2.088829	207	0.04451613	188	0.0009827960137765957	1.393977	130	396	0.02939846	
GO Biological Process	gene silencing	28	6.544693e-22	3.075771970964286e-19	2.692391	125	0.02688172	148	0.00025595784289189193	1.651327	70	180	0.01582994	
GO Biological Process	DNA packaging	30	2.355055e-21	1.0330056248333335e-18	2.450144	144	0.03096774	118	0.00001282873140338983	1.707043	80	199	0.01809136	
GO Biological Process	regulation of megakaryocyte differentiation	32	8.216658e-21	3.3788438319375003e-18	3.406099	83	0.01784946	128	0.00004787309995	2.123134	38	76	0.008593397	
GO Biological Process	chromatin silencing	33	9.535111e-21	3.8021977469393934e-18	4.036097	67	0.0144086	218	0.0020386453988990826	1.794815	41	97	0.009271823	
GO Biological Process	protein-DNA complex assembly	35	2.182954e-20	8.207283338857143e-18	2.246571	163	0.03505376	106	0.0000034865291894339624	1.706263	88	219	0.0199005	
GO Biological Process	regulation of hematopoietic progenitor cell differentiation	36	4.04595e-20	1.4789071125e-17	3.286659	84	0.01806452	192	0.001065508903125	1.766147	47	113	0.01062867	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	37	4.759503e-20	1.6927108101891893e-17	2.98979	96	0.02064516	138	0.00009281624365942029	1.87888	50	113	0.0113071	
GO Biological Process	protein folding	44	4.17602e-19	1.2489147086363634e-16	2.260749	150	0.03225806	170	0.0007932268421764706	1.540682	82	226	0.01854365	
GO Cellular Component	nucleosome	22	1.039262e-27	8.162930618181818e-26	4.725873	77	0.01655914	27	9.1377792e-9	2.224236	55	105	0.01243781	
GO Cellular Component	nuclear nucleosome	23	2.595619e-26	1.95009984e-24	9.277662	42	0.009032258	54	0.00219076704	2.229291	21	40	0.004748982	
GO Cellular Component	DNA packaging complex	24	2.471657e-22	1.7795930399999997e-20	3.83698	77	0.01655914	28	1.9702896685714286e-7	2.085221	55	112	0.01243781	
GO Cellular Component	ribosomal subunit	36	1.32939e-14	6.381072e-13	2.411652	98	0.02107527	61	0.0036055881442622955	1.514885	66	185	0.01492537	
GO Cellular Component	ficolin-1-rich granule lumen	37	3.147308e-14	1.4698778983783782e-12	2.561882	85	0.01827957	89	0.018126135586516854	1.540985	45	124	0.01017639	
GO Cellular Component	ribosome	42	4.063106e-13	1.671677897142857e-11	2.075429	120	0.02580645	58	0.0032190703448275863	1.457406	81	236	0.0183175	
GO Cellular Component	large ribosomal subunit	49	7.404998e-12	2.6113952130612245e-10	2.651978	65	0.01397849	62	0.003755833083870968	1.661583	45	115	0.01017639	
GO Cellular Component	protein-DNA complex	51	1.055667e-11	3.5768481882352947e-10	2.009877	114	0.02451613	33	0.00000572822050909091	1.702712	81	202	0.0183175	
GO Cellular Component	cytosolic ribosome	87	1.040266e-7	0.000002066183503448276	2.063563	65	0.01397849	70	0.007567785874285714	1.630264	43	112	0.009724107	
GO Cellular Component	cytosolic large ribosomal subunit	95	3.807414e-7	0.000006925485675789474	2.512457	39	0.008387097	83	0.01572433156626506	1.809885	26	61	0.005879692	
GO Cellular Component	clathrin vesicle coat	118	0.000005200815	0.00007616108745762712	2.616749	29	0.006236559	96	0.033957162	2.20806	13	25	0.002939846	
GO Cellular Component	transcription factor AP-1 complex	164	0.0001459121	0.0015374152975609755	5.450926	8	0.00172043	80	0.015619433040000002	4.246269	5	5	0.00113071	
GO Molecular Function	nucleosomal DNA binding	11	1.330693e-15	5.107441678181818e-13	3.967569	50	0.01075269	51	0.022574214435294115	2.030824	22	46	0.004975124	
GO Molecular Function	nucleosome binding	13	6.950898e-15	2.2574377966153846e-12	3.117742	65	0.01397849	62	0.03589938680322581	1.801447	28	66	0.006331976	
GO Molecular Function	rRNA methyltransferase activity	20	1.344907e-12	2.839098677e-10	5.742659	27	0.005806452	61	0.03593891675737705	2.547761	12	20	0.002713704	
GO Molecular Function	structural constituent of ribosome	25	1.195373e-11	2.0187459224e-9	2.279474	85	0.01827957	47	0.01339326195744681	1.546481	59	162	0.01334238	
GO Molecular Function	protein N-terminus binding	31	2.190876e-10	2.98383176516129e-8	2.144681	85	0.01827957	45	0.011734617417777779	1.698507	42	105	0.009497965	
GO Molecular Function	chromatin DNA binding	38	3.386649e-9	3.762745283684211e-7	2.091825	78	0.01677419	42	0.009739085431904762	1.714839	42	104	0.009497965	
GO Molecular Function	1-phosphatidylinositol-4-phosphate 3-kinase activity	66	0.000001563218	0.00009999858175757576	4.657397	15	0.003225806	81	0.049562568809876535	3.639659	6	7	0.001356852	
GO Molecular Function	peptidyl-prolyl cis-trans isomerase activity	81	0.000009884492	0.000515213891654321	2.294524	35	0.007526882	63	0.036848141650793656	2.022033	20	42	0.00452284	
GO Molecular Function	ATPase regulator activity	98	0.00004725357	0.0020357609442857145	2.312542	29	0.006236559	75	0.042166571997333334	2.065752	18	37	0.004070556	
GO Molecular Function	cyclin-dependent protein serine/threonine kinase regulator activity	124	0.000192385	0.006550398951612904	2.369666	23	0.004946237	80	0.04843104753000001	2.196346	15	29	0.00339213	
GO Molecular Function	retinoic acid receptor binding	200	0.001551872	0.032760017919999995	2.023623	23	0.004946237	58	0.03456534657586206	2.37791	14	25	0.003165988	
Mouse Phenotype Single KO	abnormal embryonic erythrocyte morphology	13	8.77856e-13	6.183482609230769e-10	3.27675	51	0.01096774	63	0.045797718055555554	2.183795	18	35	0.004070556	
Mouse Phenotype Single KO	abnormal embryonic hematopoiesis	34	4.590884e-9	0.0000012364330819999999	2.190197	69	0.01483871	37	0.0033271637767567567	2.163193	27	53	0.006105834	
Mouse Phenotype Single KO	increased hemangiosarcoma incidence	195	0.0004526326	0.0212551626574359	2.325044	21	0.004516129	59	0.04137193129322034	2.47699	14	24	0.003165988	
Mouse Phenotype	abnormal platelet aggregation	2	8.188808e-21	3.9146596644e-17	2.932053	103	0.02215054	123	0.03467828334878048	1.671404	37	94	0.008367255	
Mouse Phenotype	abnormal embryonic erythropoiesis	12	3.069071e-12	2.44528231925e-9	3.207985	50	0.01075269	88	0.0181679317125	2.328599	17	31	0.003844414	
Mouse Phenotype	abnormal embryonic erythrocyte morphology	16	1.876366e-11	1.121245957875e-8	2.930263	53	0.01139785	86	0.01728003999767442	2.177574	20	39	0.00452284	
Mouse Phenotype	abnormal embryonic hematopoiesis	48	1.918074e-8	0.00000382056364875	2.048421	74	0.01591398	38	0.0008454850169210527	2.15794	31	61	0.007010403	
Mouse Phenotype	decreased classified tumor incidence	61	9.176322e-8	0.000014382756498688525	3.008757	32	0.00688172	131	0.041270998003053436	2.274787	15	28	0.00339213