# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of intrinsic apoptotic signaling pathway	20	7.889571e-24	5.19094323945e-21	2.396443	170	0.02485744	455	0.021179959996703298	1.407635	66	155	0.01161972	
GO Biological Process	positive regulation of nuclease activity	21	8.440356e-23	5.2888878382857135e-20	6.830409	45	0.006579909	452	0.021071294176327436	2.424261	11	15	0.00193662	
GO Biological Process	cellular response to topologically incorrect protein	36	8.160396e-19	2.9828514156666666e-16	2.385343	133	0.01944729	292	0.0027206507396917807	1.5221	64	139	0.01126761	
GO Biological Process	regulation of hematopoietic progenitor cell differentiation	37	9.299402e-19	3.3073197545405403e-16	2.740141	103	0.01506068	559	0.04958205268872988	1.433493	49	113	0.008626761	
GO Biological Process	regulation of mRNA stability	38	2.217422e-18	7.678698973157894e-16	2.135863	164	0.02398011	183	0.00006958111035628415	1.620066	74	151	0.01302817	
GO Biological Process	response to topologically incorrect protein	40	3.060728e-18	1.0069029938e-15	2.151249	160	0.02339523	205	0.00015502739861463416	1.542711	84	180	0.01478873	
GO Biological Process	nuclear-transcribed mRNA catabolic process	41	4.153959e-18	1.3332182068536586e-15	2.143733	160	0.02339523	216	0.0002571398971574074	1.502641	90	198	0.01584507	
GO Biological Process	rRNA processing	42	5.576055e-18	1.7470311367857144e-15	2.033126	180	0.02631964	161	0.0000263657565447205	1.495485	114	252	0.02007042	
GO Biological Process	rRNA metabolic process	46	1.254029e-17	3.587340785e-15	2.00229	183	0.0267583	169	0.000037534225484615385	1.480594	116	259	0.02042254	
GO Biological Process	endoplasmic reticulum unfolded protein response	51	2.03019e-17	5.238288276470589e-15	2.496413	112	0.01637666	511	0.03655132425048924	1.449917	50	114	0.008802817	
GO Biological Process	mRNA catabolic process	52	3.044665e-17	7.7047589875e-15	2.047556	169	0.02471122	209	0.00020353623436363636	1.489942	96	213	0.01690141	
GO Biological Process	regulation of RNA stability	61	1.062195e-16	2.2913809844262297e-14	2.033275	166	0.02427255	207	0.00020035696332850242	1.57026	76	160	0.01338028	
GO Biological Process	cellular response to unfolded protein	68	6.036875e-16	1.1682240900735293e-13	2.322578	117	0.01710776	382	0.009960398465968587	1.502641	55	121	0.009683099	
GO Biological Process	response to unfolded protein	78	2.264273e-15	3.819944667564103e-13	2.082124	143	0.02090949	244	0.0007458310871721311	1.528937	74	160	0.01302817	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	79	3.534519e-15	5.887434876075949e-13	2.527081	94	0.0137447	485	0.027476480375257732	1.456798	52	118	0.00915493	
GO Biological Process	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	92	3.231583e-14	4.622217467065218e-12	2.673505	79	0.0115514	335	0.005389407896119403	1.726916	35	67	0.006161972	
GO Biological Process	purine nucleoside triphosphate catabolic process	94	4.236684e-14	5.93090688893617e-12	8.830317	22	0.003216845	459	0.021925155971895424	3.30581	6	6	0.001056338	
GO Biological Process	translational elongation	124	1.489839e-12	1.581031564596774e-10	2.353757	87	0.01272116	285	0.002206110043754386	1.593873	54	112	0.009507042	
GO Biological Process	RNA phosphodiester bond hydrolysis	126	1.882088e-12	1.9655869834920634e-10	2.138124	106	0.01549934	404	0.012789795591831682	1.466487	59	133	0.01038732	
GO Biological Process	cellular response to epidermal growth factor stimulus	134	6.110064e-12	6.000174042985075e-10	2.483231	74	0.0108203	395	0.012170425960759495	1.91389	22	38	0.003873239	
GO Cellular Component	endopeptidase complex	30	5.284146e-22	3.043668096e-20	3.476988	86	0.01257494	64	0.00040741596	1.820591	38	69	0.006690141	
GO Cellular Component	PcG protein complex	35	5.176219e-20	2.5555732662857145e-18	3.148769	89	0.0130136	79	0.0012639768789873417	1.940367	27	46	0.004753521	
GO Cellular Component	proteasome complex	36	7.347874e-20	3.52697952e-18	3.317141	82	0.01199006	70	0.0006888373302857142	1.798749	37	68	0.006514085	
GO Cellular Component	nuclear ubiquitin ligase complex	39	2.244298e-18	9.943966523076922e-17	4.282729	55	0.008042111	83	0.0019006194968674698	1.983486	24	40	0.004225352	
GO Cellular Component	peptidase complex	40	3.64854e-18	1.57616928e-16	2.816911	95	0.01389092	81	0.0016978069333333334	1.652905	44	88	0.007746479	
GO Cellular Component	ficolin-1-rich granule lumen	47	1.499047e-13	5.511389821276596e-12	2.213218	108	0.01579178	108	0.018342176	1.439627	54	124	0.009507042	
GO Cellular Component	catalytic step 2 spliceosome	58	1.723809e-10	5.135761986206897e-9	2.182026	83	0.01213628	119	0.026181683092436972	1.480727	43	96	0.007570423	
GO Cellular Component	large ribosomal subunit	78	1.855069e-8	4.109691323076923e-7	2.052809	74	0.0108203	118	0.02610838128813559	1.437309	50	115	0.008802817	
GO Cellular Component	LUBAC complex	93	2.047254e-7	0.0000038039300129032257	4.819869	17	0.002485744	103	0.01283036476893204	3.30581	6	6	0.001056338	
GO Cellular Component	anaphase-promoting complex	146	0.0000577036	0.0006829576767123287	2.994281	18	0.002631964	127	0.03582119508661417	2.046454	13	21	0.002288732	
GO Cellular Component	mitochondrial nucleoid	190	0.0003394085	0.0030868309894736845	2.024332	30	0.004386606	124	0.030962262193548383	1.731615	22	42	0.003873239	
GO Cellular Component	DNA polymerase complex	265	0.003640413	0.02373824024150943	2.33125	14	0.002047083	115	0.0231721344	2.203873	12	18	0.002112676	
GO Molecular Function	cadherin binding	3	2.968008e-34	4.176976592e-31	2.001689	369	0.05395526	10	7.307057620000001e-10	1.631156	150	304	0.02640845	
GO Molecular Function	ribonucleoprotein complex binding	5	2.00628e-16	1.694102832e-13	2.45903	108	0.01579178	65	0.007560289932307692	1.552293	54	115	0.009507042	
GO Molecular Function	exonuclease activity	18	9.074977e-13	2.1285862718888888e-10	2.498436	79	0.0115514	63	0.0064959015139682535	1.696402	39	76	0.006866197	
GO Molecular Function	heat shock protein binding	22	2.907198e-12	5.579177252727273e-10	2.073167	112	0.01637666	34	0.0013666763011764707	1.668647	53	105	0.009330986	
GO Molecular Function	ribonuclease activity	27	1.309228e-11	2.0472446725925925e-9	2.254079	87	0.01272116	64	0.00680719656875	1.602817	48	99	0.008450704	
GO Molecular Function	dopamine receptor binding	45	1.170217e-8	0.0000010979235942222222	4.715883	21	0.003070624	75	0.014978468210666665	2.597422	11	14	0.00193662	
GO Molecular Function	endoribonuclease activity	87	0.000002319315	0.00011255342448275863	2.156959	46	0.00672613	86	0.029696934337209303	1.711937	29	56	0.005105634	
GO Molecular Function	proteasome binding	109	0.00001225508	0.00047468759412844035	3.134472	20	0.002924404	73	0.01282782405479452	2.754842	10	12	0.001760563	
Human Phenotype	Increased serum lactate	29	1.553859e-10	3.575483140344828e-8	2.211205	81	0.01184384	2	0.0368463041	1.685963	51	100	0.008978873