# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of hematopoietic progenitor cell differentiation	13	5.611549e-41	5.680182560846153e-38	2.531822	274	0.01391569	696	0.0131928938783046	1.259315	82	113	0.007578558	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	32	6.876766e-27	2.8278551185624998e-24	2.194351	235	0.01193499	589	0.004427304218675722	1.279488	87	118	0.008040665	
GO Biological Process	regulation of mitochondrial membrane permeability	51	6.473416e-24	1.6702682577254903e-21	2.105241	228	0.01157948	391	0.00023933360347826087	1.426354	60	73	0.005545287	
GO Biological Process	negative regulation of Notch signaling pathway	82	4.832064e-20	7.754284167804878e-18	2.452231	136	0.006907059	462	0.0008778556885714286	1.577634	30	33	0.002772643	
GO Biological Process	protein targeting to mitochondrion	141	2.091391e-15	1.9518166077304967e-13	2.062196	148	0.007516506	905	0.04269128567955801	1.325213	42	55	0.003881701	
GO Biological Process	regulation of endoplasmic reticulum unfolded protein response	236	4.770693e-12	2.6600656435169497e-10	2.14426	102	0.005180295	881	0.03981286069693529	1.509041	20	23	0.001848429	
GO Biological Process	positive regulation of mitochondrial membrane permeability	244	6.786734e-12	3.660107897786885e-10	2.38502	80	0.004062976	840	0.030105426513095238	1.561858	18	20	0.001663586	
GO Biological Process	regulation of translational fidelity	374	1.571985e-9	5.530949362299465e-8	2.969416	42	0.002133062	912	0.04367212382894737	1.552724	17	19	0.001571165	
GO Biological Process	positive regulation of mitophagy	415	4.5878e-9	1.4547195228915662e-7	2.740878	45	0.002285424	863	0.03539058919698725	1.735397	11	11	0.001016636	
GO Biological Process	regulation of macromitophagy	1154	0.00004941465	0.0005634725990901213	2.237503	31	0.001574403	863	0.03539058919698725	1.735397	11	11	0.001016636	
GO Cellular Component	mitochondrial ribosome	56	8.660584e-13	2.672408777142857e-11	2.021126	126	0.006399187	122	0.03479582950819672	1.265819	62	85	0.005730129	
GO Cellular Component	mitochondrial large ribosomal subunit	71	1.278076e-10	3.1105849690140845e-9	2.212983	82	0.004164551	137	0.04969601868613138	1.327069	39	51	0.003604436	
GO Cellular Component	Seh1-associated complex	202	0.00007990215	0.0006835193821782178	2.066789	35	0.001777552	128	0.041531562	1.619704	14	15	0.0012939	
GO Molecular Function	rRNA binding	13	6.608205e-19	2.1461416546153847e-16	2.716308	106	0.005383443	89	0.0032798550074157303	1.417241	49	60	0.004528651	
GO Molecular Function	NF-kappaB binding	19	2.840332e-16	6.311516686315791e-14	2.661857	93	0.00472321	134	0.046606626492537315	1.487483	24	28	0.002218115	
GO Molecular Function	insulin-like growth factor I binding	107	3.309906e-7	0.000013060208534579438	2.125729	56	0.002844083	131	0.04308602566412213	1.735397	12	12	0.001109057	
Human Phenotype	Delayed epiphyseal ossification	78	1.121471e-7	0.000009594328183333333	3.191883	29	0.001472829	228	0.039126930627192975	1.735397	12	12	0.001109057	
Mouse Phenotype Single KO	abnormal fourth pharyngeal arch artery morphology	8	2.953717e-19	3.380898321125e-16	2.315436	146	0.007414931	505	0.03409247203168317	1.626935	15	16	0.001386322	
Mouse Phenotype Single KO	small thoracic cavity	133	3.486241e-10	2.400263822330827e-8	2.701402	53	0.002691722	466	0.02626980203218884	1.735397	12	12	0.001109057	
Mouse Phenotype Single KO	dilated kidney collecting duct	160	1.482688e-9	8.48560876e-8	2.344649	64	0.003250381	571	0.04853928447635727	1.552724	17	19	0.001571165	
Mouse Phenotype	rib bifurcation	23	1.671982e-18	6.950356479130435e-16	2.458401	124	0.006297613	754	0.026359042981432365	1.429151	28	34	0.0025878	
Mouse Phenotype	small sebaceous gland	38	1.462438e-15	3.679570978421052e-13	5.2869	37	0.001879126	890	0.043287062248314606	1.735397	10	10	0.0009242144	
Mouse Phenotype	decreased brown fat cell size	337	5.695224e-7	0.0000161578743810089	2.173768	51	0.002590147	890	0.043287062248314606	1.735397	10	10	0.0009242144