# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6	1.18442e-19	2.597630463333333e-16	3.283189	82	0.01785714	148	0.0014107381577702703	1.740453	49	118	0.0109375	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	15	9.924984e-16	8.706857630399999e-13	3.2911	64	0.01393728	218	0.009397433451376147	1.731187	38	92	0.008482143	
GO Biological Process	rRNA processing	18	2.390526e-15	1.747607313e-12	2.170062	129	0.02809233	317	0.026300860091167194	1.380466	83	252	0.01852679	
GO Biological Process	viral gene expression	19	2.494551e-15	1.7276735057368423e-12	2.828426	78	0.01698606	259	0.01539164536023166	1.584111	48	127	0.01071429	
GO Biological Process	rRNA metabolic process	20	4.745045e-15	3.12200235775e-12	2.134705	131	0.02852787	314	0.02611367090350318	1.375521	85	259	0.01897321	
GO Biological Process	nuclear-transcribed mRNA catabolic process	21	4.750926e-15	2.977020725428572e-12	2.274817	114	0.02482578	180	0.0036353535896666666	1.524107	72	198	0.01607143	
GO Biological Process	cotranslational protein targeting to membrane	23	5.775997e-15	3.3046236749130437e-12	3.130457	65	0.01415505	216	0.008775852850462963	1.710733	40	98	0.008928571	
GO Biological Process	protein localization to endoplasmic reticulum	25	8.808933e-15	4.6366699738800005e-12	2.697941	81	0.01763937	145	0.0013422316127586207	1.723839	51	124	0.01138393	
GO Biological Process	protein targeting to ER	26	1.906023e-14	9.646675637307693e-12	3.016974	66	0.01437282	261	0.01547719229195402	1.659919	40	101	0.008928571	
GO Biological Process	mRNA catabolic process	28	2.565531e-14	1.2057079438928573e-11	2.165315	120	0.0261324	154	0.0015906120690909091	1.53484	78	213	0.01741071	
GO Biological Process	establishment of protein localization to endoplasmic reticulum	36	2.713149e-13	9.917313247499999e-11	2.764605	69	0.01502613	280	0.01734508938392857	1.636601	41	105	0.009151786	
GO Biological Process	negative regulation of cyclin-dependent protein serine/threonine kinase activity	43	7.632757e-13	2.3358011479767444e-10	4.265655	37	0.008057491	412	0.04191930401213593	2.270285	13	24	0.002901786	
GO Biological Process	viral transcription	44	7.754475e-13	2.3191167392045454e-10	2.700174	69	0.01502613	299	0.022640063901003347	1.594917	43	113	0.009598214	
GO Biological Process	negative regulation of cyclin-dependent protein kinase activity	46	1.155869e-12	3.306539167608696e-10	4.013983	39	0.008493031	242	0.012091315715702478	2.418055	15	26	0.003348214	
GO Biological Process	multi-organism metabolic process	49	2.719183e-12	7.302393693265305e-10	2.348727	85	0.01851045	260	0.015484625498076922	1.539659	54	147	0.01205357	
GO Biological Process	protein targeting to membrane	60	5.922708e-11	1.2989485762000002e-8	2.281585	79	0.01720383	222	0.009693280976126126	1.595194	51	134	0.01138393	
GO Biological Process	cardiac vascular smooth muscle cell differentiation	85	3.758287e-9	5.818270427411765e-7	5.970775	18	0.003919861	229	0.01057281403580786	4.191295	6	6	0.001339286	
GO Biological Process	regulation of transcription from RNA polymerase III promoter	121	8.058604e-8	0.000008763898350082644	2.965882	33	0.007186411	427	0.04639632270023419	2.173264	14	27	0.003125	
GO Biological Process	regulation of glycolytic process	123	9.456417e-8	0.00001011682856121951	2.285621	52	0.01132404	355	0.032493047941408455	1.751586	28	67	0.00625	
GO Biological Process	positive regulation of protein sumoylation	138	2.840651e-7	0.000027087048194927534	3.879196	21	0.004573171	198	0.005621457675808081	3.429241	9	11	0.002008929	
GO Cellular Component	ribosomal subunit	18	9.898831e-16	9.50287776e-14	2.491952	100	0.021777	46	0.003850660173913043	1.517928	67	185	0.01495536	
GO Cellular Component	ribosome	19	8.245366e-13	7.498943393684211e-11	2.066616	118	0.02569686	49	0.010284343640816325	1.420778	80	236	0.01785714	
GO Cellular Component	cytosolic ribosome	22	2.225756e-10	1.7482301672727272e-8	2.314664	72	0.01567944	45	0.003439872768	1.684002	45	112	0.01004464	
GO Cellular Component	cytosolic large ribosomal subunit	25	1.662862e-9	1.1493702144e-7	2.87037	44	0.009581882	55	0.029220043287272728	1.786453	26	61	0.005803571	
GO Cellular Component	protein phosphatase type 2A complex	45	0.000002371222	0.0000910549248	2.62476	31	0.006750871	57	0.0327005507368421	2.395026	12	21	0.002678571	
GO Cellular Component	nuclear transcriptional repressor complex	100	0.0003232276	0.005585372928	2.194761	25	0.005444251	48	0.010011959999999999	2.312438	16	29	0.003571429	
GO Cellular Component	3M complex	105	0.0004080736	0.006715725531428571	6.447767	6	0.00130662	54	0.0246985024	4.191295	5	5	0.001116071	
GO Molecular Function	structural constituent of ribosome	10	1.872983e-13	7.907734226e-11	2.41689	89	0.01938153	47	0.036424748055319145	1.500587	58	162	0.01294643	
GO Molecular Function	ADP binding	74	0.00007181176	0.004097152036756757	2.007091	38	0.008275261	40	0.017513267645000004	2.212072	19	36	0.004241071	
GO Molecular Function	ATPase regulator activity	91	0.0002124927	0.009858727246153847	2.180251	27	0.005879791	44	0.025440438231818185	2.152286	19	37	0.004241071	
Mouse Phenotype Single KO	abnormal cellular replicative senescence	19	6.431974e-9	0.0000030998729430526316	2.668518	46	0.01001742	71	0.03364157987042254	1.886083	27	60	0.006026786	
Mouse Phenotype	early cellular replicative senescence	30	1.155837e-8	0.0000036836525190000002	2.377503	55	0.01197735	73	0.002367910003150685	1.95211	34	73	0.007589286	
Mouse Phenotype	abnormal cellular replicative senescence	35	2.105594e-8	0.000005751881209714286	2.256561	59	0.01284843	69	0.0019142258234782607	1.896062	38	84	0.008482143	
Mouse Phenotype	abnormal embryonic erythrocyte morphology	47	1.220295e-7	0.00002482391594680851	2.463398	44	0.009581882	212	0.02820656454622641	2.041913	19	39	0.004241071	
Mouse Phenotype	decreased B cell apoptosis	176	0.0002844464	0.015452227445454547	2.256951	24	0.005226481	257	0.040128819081712064	2.395026	12	21	0.002678571	
Mouse Phenotype	decreased abdominal adipose tissue amount	181	0.0003047782	0.016099361161325966	2.606896	18	0.003919861	202	0.02592302329009901	2.347125	14	25	0.003125