# GREAT version 4.0.4 Species assembly: hg38 Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included # Ontology Term Name Binom Rank Binom Raw P-Value Binom FDR Q-Val Binom Fold Enrichment Binom Observed Region Hits Binom Region Set Coverage Hyper Rank Hyper FDR Q-Val Hyper Fold Enrichment Hyper Observed Gene Hits Hyper Total Genes Hyper Gene Set Coverage GO Biological Process placenta blood vessel development 72 0.00002573216 0.004702909631111111 2.066441 40 0.006444337 513 0.033099810005847954 1.90708 18 31 0.003148504 GO Cellular Component mitochondrial large ribosomal subunit 14 6.887965e-7 0.00008501716800000001 2.739543 32 0.00515547 78 0.03777224123076923 1.674408 26 51 0.00454784 GO Cellular Component intraciliary transport particle B 45 0.0002160166 0.00829503744 2.886677 16 0.002577735 61 0.018831735501639343 2.18961 14 21 0.002448837 GO Cellular Component intraciliary transport particle 59 0.0005788175 0.016952485423728812 2.280595 21 0.003383277 60 0.01867885344 1.950121 19 32 0.003323421 GO Molecular Function sugar:proton symporter activity 15 0.00005003914 0.014084349938666668 3.028461 18 0.002899952 72 0.04513787111111111 2.408571 11 15 0.001924086 Human Phenotype Hypomimic face 69 0.0003634065 0.035145095282608695 3.860756 10 0.001611084 120 0.013453140575833333 3.284415 7 7 0.001224418 Mouse Phenotype Single KO increased mammary gland apoptosis 27 0.00001579425 0.0053565906388888885 3.628071 16 0.002577735 347 0.037478782939481266 2.873863 7 8 0.001224418 Mouse Phenotype Single KO increased kidney tumor incidence 44 0.00008720784 0.01814914070181818 4.625874 10 0.001611084 347 0.037478782939481266 2.873863 7 8 0.001224418 Mouse Phenotype Single KO increased renal carcinoma incidence 54 0.0001207234 0.020471558774074073 4.933534 9 0.001449976 314 0.023189032239171972 3.284415 6 6 0.001049501 Mouse Phenotype Single KO rib bifurcation 57 0.000159654 0.02564827505263158 2.261312 26 0.004188819 270 0.014297292124444444 2.038602 18 29 0.003148504 Mouse Phenotype abnormal cellular replicative senescence 2 6.846668e-11 3.2730496374e-7 2.263629 80 0.01288867 458 0.01439689326091703 1.564007 40 84 0.006996677 Mouse Phenotype early cellular replicative senescence 4 1.570467e-9 0.00000375380874675 2.238601 70 0.01127759 513 0.023240293584795322 1.574719 35 73 0.006122092 Mouse Phenotype abnormal spleen follicular dendritic cell network 10 4.568601e-7 0.0004368039416100001 15.76571 7 0.001127759 641 0.03897864576131045 3.284415 5 5 0.0008745846 Mouse Phenotype increased renal carcinoma incidence 12 8.752044e-7 0.0006973191057 5.252678 14 0.002255518 328 0.004739224463414634 2.955973 9 10 0.001574252 Mouse Phenotype rib bifurcation 16 0.000004193895 0.0025061143809375 2.327001 37 0.005961012 324 0.004576620527777778 2.028609 21 34 0.003673255 Mouse Phenotype increased mammary gland apoptosis 17 0.000005019081 0.0028227902024117644 3.467973 19 0.00306106 589 0.030759035607809845 2.463311 9 12 0.001574252 Mouse Phenotype abnormal ureter smooth muscle morphology 27 0.0000220732 0.007816365377777778 2.081165 40 0.006444337 568 0.029727623413732394 2.627532 8 10 0.001399335 Mouse Phenotype increased kidney tumor incidence 33 0.00003916644 0.011347585843636364 2.978165 19 0.00306106 275 0.0013809574634181818 2.668587 13 16 0.00227392 Mouse Phenotype abnormal neuron specification 36 0.00004557544 0.012104077273333333 2.182167 33 0.005316578 687 0.04490224143231441 2.074367 12 19 0.002099003