# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	24	5.240936e-67	2.8735615343333333e-64	2.637815	423	0.0182147	468	0.0017553428367735042	1.288239	88	113	0.007752621	
GO Biological Process	regulation of DNA-templated transcription in response to stress	27	2.017185e-63	9.831162005555555e-61	2.475272	449	0.01933428	408	0.0009751267309068627	1.29279	93	119	0.008193111	
GO Biological Process	cellular response to insulin stimulus	29	6.28964e-62	2.8539783710344826e-59	2.065985	644	0.02773113	470	0.0018003438253617022	1.251839	112	148	0.009866972	
GO Biological Process	liver regeneration	53	6.423953e-50	1.5949584439056603e-47	3.303743	220	0.009473367	440	0.00139319267625	1.512426	32	35	0.002819135	
GO Biological Process	endoplasmic reticulum unfolded protein response	57	3.900084e-49	9.003720237894737e-47	2.402447	366	0.01576024	566	0.005765990160777386	1.262428	87	114	0.007664523	
GO Biological Process	regulation of intrinsic apoptotic signaling pathway	64	1.369056e-47	2.814907485e-45	2.059084	496	0.02135814	555	0.005148227578378378	1.227321	115	155	0.01013127	
GO Biological Process	nuclear-transcribed mRNA catabolic process	66	2.866472e-46	5.715137128484848e-44	2.012312	510	0.02196099	329	0.00014305528871124619	1.253194	150	198	0.01321469	
GO Biological Process	cellular response to topologically incorrect protein	85	4.990666e-44	7.72613810517647e-42	2.160214	409	0.01761185	713	0.017184631547545584	1.213885	102	139	0.008985992	
GO Biological Process	cellular response to unfolded protein	89	1.684941e-42	2.4912515302247192e-40	2.203941	377	0.01623391	493	0.002570494007342799	1.271422	93	121	0.008193111	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to hypoxia	97	1.100492e-41	1.49292517814433e-39	2.528207	280	0.01205701	498	0.0026227741943373496	1.336097	63	78	0.005550172	
GO Biological Process	cellular response to epidermal growth factor stimulus	98	1.288709e-41	1.7304205847959183e-39	2.608937	264	0.01136804	605	0.008110639914214877	1.436556	33	38	0.002907233	
GO Biological Process	response to epidermal growth factor	114	4.503706e-39	5.198619934561404e-37	2.481665	271	0.01166947	599	0.0076874196983305505	1.417899	36	42	0.003171527	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	118	1.501244e-38	1.674141508135593e-36	2.351376	297	0.01278905	623	0.00905148045987159	1.247671	89	118	0.007840719	
GO Biological Process	platelet-derived growth factor receptor signaling pathway	167	7.627741e-32	6.01038585742515e-30	2.33269	247	0.01063601	505	0.002799805252475247	1.503832	30	33	0.002642939	
GO Biological Process	regulation of necrotic cell death	168	8.642359e-32	6.769333457202382e-30	4.187554	102	0.004392197	745	0.021727893516778524	1.470414	24	27	0.002114351	
GO Biological Process	triglyceride homeostasis	200	3.596694e-29	2.3664448172999998e-27	3.151103	134	0.005770142	905	0.047272624245303874	1.395744	27	32	0.002378645	
GO Biological Process	cotranslational protein targeting to membrane	209	2.491635e-28	1.5687763141148326e-26	2.247449	236	0.01016234	503	0.0027144270091451297	1.299741	77	98	0.006783543	
GO Biological Process	protein targeting to ER	222	9.648414e-27	5.719075667837839e-25	2.169314	240	0.01033458	510	0.00289277651254902	1.293891	79	101	0.006959739	
GO Biological Process	regulation of mitochondrial membrane permeability	242	1.19526e-25	6.499349727272728e-24	2.051142	262	0.01128192	726	0.019465042929752065	1.291648	57	73	0.005021584	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	244	1.435656e-25	7.742539878688523e-24	2.21667	218	0.009387245	554	0.0051479053119133575	1.294603	72	92	0.006343053	
GO Cellular Component	PcG protein complex	73	9.892839e-20	2.341756957808219e-18	2.052538	197	0.008482969	91	0.0015351525415384618	1.438448	40	46	0.003523919	
GO Cellular Component	mitochondrial ribosome	83	1.719367e-17	3.5795978024096387e-16	2.135256	157	0.006760539	150	0.03285188352000001	1.245527	64	85	0.00563827	
GO Cellular Component	spliceosomal snRNP complex	116	2.34364e-14	3.4912154482758623e-13	2.073442	135	0.005813202	112	0.008571336685714286	1.334045	50	62	0.004404898	
GO Cellular Component	Fanconi anaemia nuclear complex	216	2.695163e-8	2.1561304e-7	2.196072	62	0.002669767	133	0.018655812812030072	1.654215	13	13	0.001145274	
GO Cellular Component	U1 snRNP	290	0.000003861974	0.000023012038179310346	2.028146	51	0.002196099	121	0.013416403358677685	1.567152	18	19	0.001585763	
Human Phenotype	Menorrhagia	20	1.011847e-21	3.3760275154999997e-19	3.51323	84	0.003617104	209	0.029995256327272728	1.567152	18	19	0.001585763	
Human Phenotype	Abnormal platelet volume	251	1.816094e-9	4.8282052836653384e-8	2.297914	66	0.00284201	209	0.029995256327272728	1.567152	18	19	0.001585763	
Human Phenotype	Abnormality of monocarboxylic acid metabolism	284	8.497434e-9	1.9965977845774644e-7	2.287154	61	0.002626706	232	0.04130049133189655	1.654215	13	13	0.001145274	
Mouse Phenotype Single KO	decreased circulating free fatty acid level	79	1.825497e-34	2.1159589910126584e-32	2.044584	361	0.01554493	399	0.04303156583458646	1.245108	70	93	0.006166858	
Mouse Phenotype Single KO	pale liver	103	2.59419e-31	2.306310468932039e-29	2.142243	292	0.01257374	286	0.012439569982867134	1.302695	63	80	0.005550172	
Mouse Phenotype Single KO	increased hepatocyte apoptosis	258	5.822502e-19	2.0665368532558137e-17	2.102216	178	0.007664815	217	0.0034559665789861754	1.457285	37	42	0.003259625	
Mouse Phenotype	decreased circulating free fatty acid level	54	8.566253e-48	1.5167026839444444e-45	2.071487	491	0.02114283	299	0.0022636393368561875	1.278889	92	119	0.008105013	
Mouse Phenotype	increased respiratory quotient	314	2.279903e-20	6.942086809872612e-19	2.056462	203	0.008741334	634	0.04766187152839117	1.299741	44	56	0.00387631	
Mouse Phenotype	increased follicular B cell number	374	1.111647e-17	2.8418334136363635e-16	2.112037	163	0.007018904	465	0.01693970689032258	1.447439	28	32	0.002466743	
Mouse Phenotype	increased cellular sensitivity to ultraviolet irradiation	770	5.679318e-10	7.051942778961039e-9	2.108864	85	0.003660164	403	0.008749937760297767	1.488794	27	30	0.002378645