# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	80	8.892667e-46	1.4627325631625e-43	2.222442	401	0.01208778	396	0.000010751311726515151	1.238606	110	118	0.007783753	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	111	6.866008e-35	8.139621556036037e-33	2.199498	309	0.009314523	498	0.000126153298375502	1.242033	86	92	0.00608548	
GO Biological Process	cotranslational protein targeting to membrane	114	1.970549e-34	2.274601253596491e-32	2.146615	322	0.009706397	441	0.0000373597735941043	1.247339	92	98	0.006510048	
GO Biological Process	intrinsic apoptotic signaling pathway in response to DNA damage	122	5.977164e-33	6.447008284918033e-31	2.135897	311	0.009374812	599	0.0007986998942237062	1.251661	65	69	0.004599491	
GO Biological Process	protein targeting to ER	126	3.616354e-32	3.776793832222222e-30	2.06909	327	0.009857117	419	0.00001996475942625298	1.249755	95	101	0.006722332	
GO Biological Process	mitochondrial transmembrane transport	145	1.697869e-28	1.5408453911034482e-26	2.010238	309	0.009314523	805	0.007019304838509317	1.20062	75	83	0.005307104	
GO Biological Process	gene silencing by miRNA	187	2.204402e-24	1.5512152897326205e-22	2.142847	224	0.006752276	631	0.0011800628336925516	1.298489	43	44	0.00304274	
GO Biological Process	histone ubiquitination	268	5.622872e-20	2.7608721137313435e-18	2.016737	209	0.006300115	953	0.019751258568730324	1.260549	37	39	0.002618172	
GO Biological Process	maintenance of protein localization in organelle	372	2.060491e-16	7.288709964784946e-15	2.378792	116	0.003496714	701	0.002778852294293866	1.328687	31	31	0.002193603	
GO Biological Process	histone monoubiquitination	375	2.287322e-16	8.026365386133335e-15	2.104972	151	0.004551757	1097	0.042637715029170464	1.281234	27	28	0.001910558	
GO Biological Process	cytoplasmic translation	398	1.197947e-15	3.960749892713568e-14	2.205603	129	0.003888587	833	0.008683698346458582	1.266887	41	43	0.002901217	
GO Cellular Component	mitochondrial ribosome	61	6.702526e-21	1.8986827750819673e-19	2.037439	214	0.006450835	138	0.001081020271304348	1.219265	78	85	0.005519389	
GO Cellular Component	precatalytic spliceosome	149	2.241156e-10	2.59913930738255e-9	2.186872	82	0.002471815	165	0.003642089890909091	1.328687	28	28	0.001981319	
GO Cellular Component	spliceosomal tri-snRNP complex	163	4.292913e-9	4.5510145177914114e-8	2.006922	86	0.002592392	215	0.022184377451162793	1.28287	28	29	0.001981319	
GO Molecular Function	rRNA binding	22	3.908833e-26	7.501405875454546e-24	2.555232	168	0.005064207	96	0.00035806192679166664	1.284397	58	60	0.004104161	
GO Molecular Function	snRNA binding	116	2.032471e-10	7.397493587931035e-9	2.049476	96	0.002893833	172	0.04447251063953488	1.258756	36	38	0.00254741	
Mouse Phenotype Single KO	abnormal interventricular septum thickness	52	4.496868e-23	7.918811591538462e-21	2.002144	249	0.007505878	344	0.0019601735068023258	1.297787	42	43	0.002971978	
Mouse Phenotype Single KO	increased squamous cell carcinoma incidence	120	3.679406e-16	2.8076933951666668e-14	2.181958	137	0.00412974	485	0.01160248730041237	1.328687	26	26	0.001839796	
Mouse Phenotype	abnormal third pharyngeal arch artery morphology	111	7.708447e-21	6.639681240270271e-19	2.070606	205	0.006179538	983	0.024801496611393692	1.328687	21	21	0.001485989	
Mouse Phenotype	increased embryonic neuroepithelium apoptosis	297	6.92959e-13	2.2307680131313132e-11	2.010612	129	0.003888587	806	0.009689934711290323	1.328687	25	25	0.001769035	
Mouse Phenotype	tachypnea	310	1.021367e-12	3.150093511935484e-11	2.278756	95	0.002863688	1190	0.04810453247142857	1.328687	18	18	0.001273705