# GREAT version 4.0.4 Species assembly: hg38 Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included # Ontology Term Name Binom Rank Binom Raw P-Value Binom FDR Q-Val Binom Fold Enrichment Binom Observed Region Hits Binom Region Set Coverage Hyper Rank Hyper FDR Q-Val Hyper Fold Enrichment Hyper Observed Gene Hits Hyper Total Genes Hyper Gene Set Coverage GO Biological Process forebrain neuroblast division 426 0.00002570797 0.0007941107446713616 2.318877 31 0.0030185 760 0.02523736906842105 2.261744 8 8 0.0009636232 GO Biological Process positive regulation of extracellular matrix assembly 573 0.0001070292 0.0024579358513089006 2.083978 33 0.003213242 645 0.013140769174573644 2.261744 9 9 0.001084076 Human Phenotype Pancreatic islet-cell hyperplasia 11 6.288565e-10 3.814872204090909e-7 3.284736 38 0.003700097 99 0.04341537381010101 2.261744 9 9 0.001084076 Mouse Phenotype Single KO enlarged allantois 86 1.153146e-7 0.00001227832316511628 2.295562 51 0.00496592 854 0.030466722200234192 1.837667 13 16 0.001565888 Mouse Phenotype Single KO abnormal conotruncus morphology 103 3.628688e-7 0.000032260093219417475 2.005029 64 0.006231743 408 0.002145329565661765 2.110961 14 15 0.001686341 Mouse Phenotype Single KO abnormal conotruncal ridge morphology 112 4.65689e-7 0.000038074233687499996 2.002195 63 0.006134372 470 0.003948640625744681 2.100191 13 14 0.001565888 Mouse Phenotype Single KO decreased molar number 115 5.769754e-7 0.000045942293372173913 2.582255 36 0.003505355 733 0.01820891311869031 2.261744 8 8 0.0009636232 Mouse Phenotype Single KO osteomalacia 553 0.0006965531 0.01153406281500904 2.426164 18 0.001752678 893 0.03382084115453528 2.261744 7 7 0.0008431703 Mouse Phenotype abnormal hair follicle orientation 87 4.44994e-9 4.890330613793103e-7 2.002441 86 0.008373905 1003 0.011195664092721836 1.658612 22 30 0.002649964 Mouse Phenotype delayed hair appearance 92 7.949716e-9 8.261655943043479e-7 2.123992 72 0.007010711 1436 0.036163816692200555 1.591598 19 27 0.002288605 Mouse Phenotype enlarged allantois 151 2.514712e-7 0.000015922623464900662 2.14344 56 0.005452775 934 0.008094583160492505 1.884787 15 18 0.001806794 Mouse Phenotype decreased molar number 184 0.000001087064 0.000056485972304347826 2.439772 38 0.003700097 906 0.006797242042384106 2.261744 9 9 0.001084076 Mouse Phenotype ectopic ureteric bud 210 0.000002409395 0.00010969631235714285 2.06252 51 0.00496592 954 0.008998591713522014 2.073265 11 12 0.001324982 Mouse Phenotype absent metanephric mesenchyme 340 0.00002869354 0.0008068792233529411 2.237672 33 0.003213242 1509 0.047284125083499 2.261744 6 6 0.0007227174 Mouse Phenotype abnormal brown adipose tissue thermogenesis 544 0.0002597796 0.004565721977205883 2.119657 28 0.002726388 1331 0.0278681743703982 2.03557 9 10 0.001084076 Mouse Phenotype decreased diameter of tibia 754 0.0009814274 0.012444863887798408 2.352189 18 0.001752678 1509 0.047284125083499 2.261744 6 6 0.0007227174 Mouse Phenotype kidney corticomedullary cysts 986 0.002640914 0.025608294882352937 2.093552 19 0.001850049 1509 0.047284125083499 2.261744 6 6 0.0007227174 Mouse Phenotype ectopic Bergmann glia cells 1236 0.00627242 0.0485199090776699 2.119315 15 0.001460565 1509 0.047284125083499 2.261744 6 6 0.0007227174