# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	platelet-derived growth factor receptor signaling pathway	451	4.887889e-22	1.42615812308204e-20	2.049549	223	0.009345011	748	0.006689112007085561	1.431327	30	33	0.002515512	
GO Biological Process	gene silencing by miRNA	458	7.563884e-22	2.1732128724017468e-20	2.287412	172	0.007207811	1027	0.030408386099318403	1.323977	37	44	0.003102465	
GO Biological Process	lymph vessel development	628	7.669818e-17	1.6071199850636944e-15	2.138749	150	0.006285882	1148	0.04723334788414635	1.431327	20	22	0.001677008	
GO Biological Process	positive regulation of G2/M transition of mitotic cell cycle	664	4.868381e-16	9.648046020933735e-15	2.172897	137	0.005741105	858	0.014451762858508157	1.499485	20	21	0.001677008	
GO Biological Process	regulation of Rac protein signal transduction	721	5.176742e-15	9.448092646047158e-14	2.476134	97	0.00406487	963	0.023689028570093456	1.574459	14	14	0.001173906	
GO Biological Process	positive regulation of extracellular matrix organization	745	9.612126e-15	1.6977982017986578e-13	2.272221	113	0.004735364	1086	0.0387419498922652	1.486989	17	18	0.001425457	
GO Biological Process	glucose import	1074	1.905765e-10	2.3350057388268154e-9	2.636169	57	0.002388635	1052	0.03415561047528517	1.574459	13	13	0.001090055	
GO Biological Process	regulation of DNA damage checkpoint	1220	2.170123e-9	2.3407088981147542e-8	2.047072	85	0.003562	881	0.0164391757446084	1.574459	15	15	0.001257756	
GO Biological Process	regulation of RNA export from nucleus	1402	3.251584e-8	3.051896851355207e-7	2.396432	51	0.0021372	1167	0.04849509836675236	1.574459	12	12	0.001006205	
GO Biological Process	endoplasmic reticulum tubular network organization	2256	0.00002309373	0.0001347031884175532	2.038078	42	0.001760047	1167	0.04849509836675236	1.574459	12	12	0.001006205	
GO Cellular Component	cytoplasmic stress granule	117	3.084986e-18	4.556287015384616e-17	2.143303	163	0.006830658	170	0.03230269327058824	1.318152	36	43	0.003018615	
GO Cellular Component	methylosome	224	4.191344e-9	3.233322514285714e-8	3.378626	33	0.001382894	186	0.03995550348387097	1.574459	12	12	0.001006205	
GO Cellular Component	Sin3 complex	287	7.223498e-7	0.000004349200189547039	2.087296	55	0.002304823	166	0.028424350843373494	1.574459	13	13	0.001090055	
Mouse Phenotype Single KO	abnormal liver sinusoid morphology	100	1.397303e-33	1.2795103571000002e-31	2.217163	291	0.01219461	453	0.0022477463523178807	1.335905	56	66	0.004695623	
Mouse Phenotype Single KO	enlarged liver sinusoidal spaces	145	2.117946e-27	1.3375194153103448e-25	2.411662	197	0.008255458	434	0.0018166595508986175	1.4468	34	37	0.002850914	
Mouse Phenotype Single KO	increased integument system tumor incidence	160	7.107083e-26	4.0674724394375e-24	2.106689	248	0.01039266	836	0.030136869961722487	1.242994	60	76	0.005031025	
Mouse Phenotype Single KO	abnormal cellular replicative senescence	163	2.254667e-25	1.2666248907361963e-23	2.277295	204	0.008548799	412	0.0013092102953640775	1.364531	52	60	0.004360221	
Mouse Phenotype Single KO	abnormal Mullerian duct morphology	241	4.469498e-20	1.6982237836514522e-18	2.1046	189	0.007920211	656	0.012485312657317072	1.394521	31	35	0.002599363	
Mouse Phenotype Single KO	early cellular replicative senescence	275	1.930478e-18	6.428140743999999e-17	2.126768	168	0.007040188	502	0.003716627472709163	1.362513	45	52	0.003773268	
Mouse Phenotype Single KO	increased mammary gland tumor incidence	395	8.9754e-15	2.08070222278481e-13	2.164817	126	0.005280141	704	0.017186388289772727	1.367293	33	38	0.002767064	
Mouse Phenotype Single KO	absent heart	1558	0.00002049573	0.00012046174557766367	2.069366	41	0.001718141	914	0.0430876523654267	1.574459	12	12	0.001006205	
Mouse Phenotype	abnormal liver sinusoid morphology	108	2.3568e-44	2.0864226666666667e-42	2.217209	389	0.01630139	533	0.00017477106186866793	1.35242	67	78	0.005617978	
Mouse Phenotype	enlarged liver sinusoidal spaces	131	9.971272e-40	7.277506228396946e-38	2.600619	253	0.01060219	585	0.0003080966058461539	1.459255	38	41	0.003186316	
Mouse Phenotype	abnormal cellular replicative senescence	217	3.143995e-28	1.385241299308756e-26	2.075492	282	0.01181746	766	0.0018902184372062666	1.293306	69	84	0.005785678	
Mouse Phenotype	early cellular replicative senescence	223	5.787248e-28	2.4812501402690586e-26	2.146125	258	0.01081172	891	0.00423131337003367	1.294076	60	73	0.005031025	
Mouse Phenotype	increased pulmonary respiratory rate	328	5.327379e-21	1.5528984944817074e-19	2.212719	177	0.007417341	1296	0.025360095106481483	1.349536	30	35	0.002515512	
Mouse Phenotype	increased large intestine adenocarcinoma incidence	348	3.775337e-20	1.0372412947413793e-18	3.717949	72	0.003017223	1030	0.01021642975631068	1.574459	15	15	0.001257756	
Mouse Phenotype	decreased classified tumor incidence	358	8.423907e-20	2.2497479001955305e-18	2.455104	134	0.005615388	1192	0.018384656000838925	1.405767	25	28	0.00209626	
Mouse Phenotype	increased colon adenocarcinoma incidence	462	1.170846e-16	2.4230429883116884e-15	3.547286	62	0.002598165	1236	0.021122229271844657	1.574459	13	13	0.001090055	
Mouse Phenotype	tachypnea	470	1.678381e-16	3.414255476808511e-15	2.834432	85	0.003562	848	0.0031747368148584906	1.574459	18	18	0.001509307	
Mouse Phenotype	increased mouth tumor incidence	678	8.583029e-13	1.2103590010176992e-11	2.122343	112	0.004693458	1160	0.01612319235	1.443254	22	24	0.001844709	
Mouse Phenotype	abnormal coronary circulation	698	1.451281e-12	1.9879222981375357e-11	2.241499	97	0.00406487	1122	0.014772742002673795	1.574459	14	14	0.001173906	
Mouse Phenotype	increased circulating erythropoietin level	699	1.462975e-12	2.0010735300429182e-11	2.262946	95	0.003981059	1397	0.03272202631352899	1.481844	16	17	0.001341607	
Mouse Phenotype	abnormal serous gland morphology	749	7.182219e-12	9.168116937116155e-11	2.339658	83	0.003478188	1357	0.030301859783345615	1.574459	12	12	0.001006205	
Mouse Phenotype	decreased transitional stage T1 B cell number	1379	2.696573e-7	0.0000018696109102973169	2.108354	58	0.002430541	902	0.0047016970084257205	1.574459	17	17	0.001425457	
Mouse Phenotype	absent heart	1476	6.372025e-7	0.000004127569852642277	2.036536	59	0.002472447	1030	0.01021642975631068	1.574459	15	15	0.001257756	
Mouse Phenotype	decreased susceptibility to induced choroidal neovascularization	1986	0.00003209941	0.0001545329602265861	2.115338	37	0.001550518	1503	0.04308913694011977	1.574459	11	11	0.0009223545