# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of gene expression, epigenetic	17	1.180934e-53	9.141123827058824e-51	2.139572	509	0.03277105	325	0.00004160163189538462	1.252962	180	248	0.01654868	
GO Biological Process	nuclear-transcribed mRNA catabolic process	23	3.539169e-43	2.02486629873913e-40	2.218216	376	0.02420809	88	3.2405233772727277e-18	1.517054	174	198	0.01599706	
GO Biological Process	mRNA catabolic process	25	8.061791e-42	4.2434043107599997e-39	2.128566	399	0.0256889	91	1.837725206153846e-17	1.491267	184	213	0.01691643	
GO Biological Process	RNA catabolic process	30	2.893719e-40	1.2692816107e-37	2.010659	440	0.02832861	100	1.23256431618e-16	1.454106	203	241	0.01866323	
GO Biological Process	rRNA processing	36	5.990363e-38	2.1896440754722223e-35	2.024191	407	0.02620397	85	2.063883878e-18	1.465988	214	252	0.01967454	
GO Biological Process	gene silencing	44	8.328918e-35	2.4909143627727275e-32	2.127981	330	0.02124646	490	0.0023652421652653063	1.237184	129	180	0.01185989	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	48	2.868184e-33	7.863006928333333e-31	2.55688	216	0.01390677	147	1.0572674639455782e-11	1.536117	105	118	0.009653397	
GO Biological Process	multi-organism metabolic process	60	5.574101e-29	1.2224932509833333e-26	2.156711	264	0.01699717	127	2.468961001496063e-13	1.514919	129	147	0.01185989	
GO Biological Process	viral gene expression	63	1.764067e-28	3.684659944920635e-26	2.337121	218	0.01403554	126	2.362799753412698e-13	1.549595	114	127	0.01048083	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	72	3.342075e-27	6.108106239583333e-25	2.200427	236	0.01519444	317	0.00003504465029400631	1.374932	90	113	0.00827434	
GO Biological Process	viral transcription	86	2.151594e-25	3.2921890053488376e-23	2.302344	199	0.01281226	137	2.6890358869343063e-12	1.558256	102	113	0.009377586	
GO Biological Process	regulation of DNA-templated transcription in response to stress	88	1.431085e-24	2.139959944886364e-22	2.052423	249	0.01603142	286	0.000005255644786363637	1.392648	96	119	0.008825963	
GO Biological Process	ribonucleoprotein complex export from nucleus	93	9.790162e-24	1.3852552877204299e-21	2.163106	212	0.01364924	250	2.26798049436e-7	1.422474	103	125	0.009469523	
GO Biological Process	translational initiation	96	2.206919e-23	3.0250882417708335e-21	2.045818	238	0.0153232	177	3.865904548135593e-10	1.460718	121	143	0.01112439	
GO Biological Process	cotranslational protein targeting to membrane	104	3.578895e-22	4.528334548557692e-20	2.349377	165	0.01062323	216	3.41368706675926e-8	1.497304	85	98	0.007814655	
GO Biological Process	ribonucleoprotein complex localization	108	5.888926e-22	7.175220114259259e-20	2.086615	212	0.01364924	270	0.000001125982976185185	1.400073	103	127	0.009469523	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	119	2.686809e-20	2.9710688765546217e-18	2.326093	153	0.009850631	234	7.782727468376069e-8	1.501133	80	92	0.007354969	
GO Biological Process	DNA-templated transcription, termination	128	9.207589e-20	9.465833097734375e-18	2.135928	179	0.01152459	350	0.00011544495972	1.362037	86	109	0.007906592	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to hypoxia	130	1.20492e-19	1.2196570984615386e-17	2.21406	164	0.01055885	360	0.0001834997694111111	1.416454	64	78	0.005883975	
GO Biological Process	snRNA metabolic process	131	2.536016e-19	2.5474377514503816e-17	2.310714	147	0.009464332	283	0.000003167753980459364	1.46535	73	86	0.006711409	
GO Cellular Component	ribosomal subunit	35	4.729569e-29	2.3350557805714283e-27	2.092341	284	0.01828483	39	4.888999384615384e-15	1.483688	159	185	0.014618	
GO Cellular Component	methyltransferase complex	46	9.460322e-21	3.553790525217391e-19	2.125105	191	0.01229719	117	0.0016647463384615385	1.327926	70	91	0.006435598	
GO Cellular Component	histone methyltransferase complex	50	1.032226e-19	3.567373056e-18	2.193779	168	0.01081638	116	0.0016604635034482757	1.376039	55	69	0.005056541	
GO Cellular Component	large ribosomal subunit	51	2.175706e-19	7.371803858823529e-18	2.137569	175	0.01126706	55	3.711143912727273e-10	1.501133	100	115	0.009193712	
GO Cellular Component	pronucleus	57	8.012432e-18	2.429032016842105e-16	4.035088	57	0.003669843	181	0.03141985166850829	1.611216	14	15	0.00128712	
GO Cellular Component	mitochondrial ribosome	72	5.438417e-14	1.3052200799999999e-12	2.236835	110	0.007082153	92	0.00008547867547826089	1.401352	69	85	0.006343661	
GO Cellular Component	PcG protein complex	73	7.583894e-14	1.7952012098630136e-12	2.056316	132	0.008498584	90	0.0000764337984	1.538662	41	46	0.003769422	
GO Cellular Component	cytoplasmic stress granule	78	4.075344e-13	9.0284544e-12	2.181812	108	0.006953387	153	0.011232705882352942	1.405131	35	43	0.003217799	
GO Cellular Component	small ribosomal subunit	86	5.196264e-12	1.0440865339534882e-10	2.05025	113	0.007275303	80	0.000020622297600000002	1.462562	61	72	0.005608164	
GO Cellular Component	cytosolic large ribosomal subunit	91	1.285347e-11	2.4407468307692305e-10	2.063685	107	0.006889003	74	0.0000043270380972972966	1.528203	54	61	0.004964604	
GO Cellular Component	intrinsic component of mitochondrial outer membrane	99	2.13382e-10	3.7244858181818184e-9	2.771314	52	0.003347927	148	0.0061710125837837835	1.57619	21	23	0.001930679	
GO Cellular Component	integral component of mitochondrial outer membrane	106	8.033043e-10	1.3095375758490566e-8	2.725168	50	0.00321916	151	0.009596038315231788	1.569367	20	22	0.001838742	
GO Cellular Component	mitochondrial large ribosomal subunit	111	1.494554e-9	2.3266570378378377e-8	2.292226	67	0.004313675	111	0.0007991360172972974	1.455511	43	51	0.003953296	
GO Cellular Component	proton-transporting two-sector ATPase complex	120	2.56668e-9	3.6960192e-8	2.038371	85	0.005472573	208	0.04973332707692308	1.30287	40	53	0.003677485	
GO Cellular Component	nuclear ubiquitin ligase complex	121	3.199733e-9	4.569536052892562e-8	2.262909	66	0.004249292	152	0.010001122863157894	1.4242	33	40	0.003033925	
GO Cellular Component	outer mitochondrial membrane protein complex	128	1.269919e-8	1.71439065e-7	3.293083	32	0.002060263	181	0.03141985166850829	1.611216	14	15	0.00128712	
GO Cellular Component	mitochondrial outer membrane translocase complex	129	1.654325e-8	2.2160260465116282e-7	3.59661	28	0.00180273	172	0.024706029767441864	1.726303	11	11	0.001011308	
GO Cellular Component	exon-exon junction complex	160	6.803863e-7	0.00000734817204	2.394069	41	0.002639712	161	0.01422473500621118	1.561893	19	21	0.001746805	
GO Cellular Component	nuclear pore outer ring	170	0.000001263096	0.000012838999341176468	3.298112	23	0.001480814	191	0.03842229713089006	1.726303	10	10	0.0009193712	
GO Cellular Component	endoplasmic reticulum subcompartment	177	0.000002148496	0.00002097514738983051	2.107109	49	0.003154777	196	0.038865638204081634	1.490898	19	22	0.001746805	
GO Molecular Function	ribonucleoprotein complex binding	8	5.261925e-27	2.7769809187500002e-24	2.245708	224	0.01442184	42	3.7296786114285714e-7	1.441088	96	115	0.008825963	
GO Molecular Function	rRNA binding	10	1.253241e-19	5.291183502e-17	3.021165	93	0.005987638	43	6.981816340930232e-7	1.582445	55	60	0.005056541	
GO Molecular Function	unfolded protein binding	14	4.873502e-15	1.469708960285714e-12	2.017039	152	0.009786248	139	0.035692818374100724	1.254013	77	106	0.007079158	
GO Molecular Function	snRNA binding	23	1.927285e-12	3.5378249e-10	2.827051	62	0.003991759	82	0.0001792760056585366	1.590016	35	38	0.003217799	
GO Molecular Function	O-methyltransferase activity	29	6.348397e-12	9.242390391034483e-10	2.922013	56	0.00360546	116	0.006162220099999999	1.644098	20	21	0.001838742	
GO Molecular Function	protein binding involved in protein folding	41	2.308094e-10	2.376773870243902e-8	2.595707	58	0.003734226	128	0.017203548321874998	1.534492	24	27	0.002206491	
GO Molecular Function	ribosomal small subunit binding	55	5.462262e-9	4.1930309389090915e-7	2.655941	47	0.003026011	126	0.01599480239206349	1.726303	14	14	0.00128712	
GO Molecular Function	H4 histone acetyltransferase activity	77	4.225541e-8	0.0000023169135197402596	2.793814	38	0.002446562	140	0.03733306515714285	1.624756	16	17	0.001470994	
Mouse Phenotype Single KO	abnormal DNA repair	7	1.557288e-17	2.0371551737142854e-14	2.085926	166	0.01068761	194	0.017001839660824743	1.299368	70	93	0.006435598	
Mouse Phenotype Single KO	absent hypoglossal nerve	74	6.814119e-9	8.432011849054054e-7	2.904333	40	0.002575328	187	0.013532885460427808	1.726303	15	15	0.001379057	
Mouse Phenotype	abnormal DNA repair	5	1.228125e-22	2.3484206249999997e-19	2.099126	216	0.01390677	166	0.000990892248614458	1.315952	93	122	0.008550152	
Mouse Phenotype	abnormal embryonic erythrocyte morphology	42	4.116128e-12	9.370071382857144e-10	2.002819	121	0.007790368	362	0.03346157195303867	1.416454	32	39	0.002941988	
Mouse Phenotype	absent hypoglossal nerve	100	6.814119e-9	6.514979175899999e-7	2.904333	40	0.002575328	266	0.009933458459774436	1.726303	15	15	0.001379057	
Mouse Phenotype	increased kidney tumor incidence	226	0.000004675831	0.00019781247872123896	2.317668	37	0.002382179	405	0.04773075470370371	1.618409	15	16	0.001379057	
Mouse Phenotype	increased interleukin-12b secretion	283	0.00001941774	0.0006560177107420496	2.142094	38	0.002446562	310	0.023307395602258064	1.630397	17	18	0.001562931