# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	139	1.233352e-52	1.1676028034532373e-50	2.166884	491	0.0117856	396	0.000008261572435858586	1.210377	113	118	0.007606354	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	182	5.819109e-43	4.2073436995054945e-41	2.193533	387	0.009289263	376	0.000004630589104787235	1.236457	90	92	0.006058158	
GO Biological Process	cotranslational protein targeting to membrane	191	5.90411e-42	4.067653585863874e-40	2.133991	402	0.009649312	338	0.0000014170117315384616	1.238139	96	98	0.006462036	
GO Biological Process	protein targeting to ER	213	4.04542e-38	2.4992338863849762e-36	2.040586	405	0.009721322	384	0.0000059544509268229175	1.226391	98	101	0.006596661	
GO Biological Process	intrinsic apoptotic signaling pathway in response to DNA damage	216	1.963522e-37	1.1962030554629628e-35	2.078125	380	0.00912124	948	0.025845289298523207	1.172344	64	69	0.004308024	
GO Biological Process	gene silencing by miRNA	251	1.822334e-33	9.553821954581673e-32	2.216687	291	0.00698495	589	0.0007369748217826825	1.263934	44	44	0.002961766	
GO Biological Process	axonal transport	260	1.604176e-32	8.118981532307692e-31	2.274554	267	0.006408872	879	0.01808399901934016	1.231525	38	39	0.002557889	
GO Biological Process	posttranscriptional gene silencing by RNA	271	3.141002e-31	1.5251824840590408e-29	2.064603	319	0.007657041	511	0.00016408268692759295	1.263934	51	51	0.003432956	
GO Biological Process	posttranscriptional gene silencing	281	1.280362e-30	5.995830447686834e-29	2.044551	320	0.007681045	505	0.0001312670442653465	1.263934	52	52	0.003500269	
GO Biological Process	axo-dendritic transport	326	3.368253e-27	1.3595963566564418e-25	2.033344	286	0.006864934	929	0.02503232745532831	1.20898	44	46	0.002961766	
GO Biological Process	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	370	5.598846e-24	1.991222013891892e-22	2.001578	260	0.006240849	943	0.025694015011664902	1.229773	36	37	0.002423263	
GO Biological Process	production of miRNAs involved in gene silencing by miRNA	462	4.990043e-20	1.4212981782900433e-18	2.138199	182	0.004368594	934	0.025128956141327624	1.263934	27	27	0.001817447	
GO Biological Process	cellular component disassembly involved in execution phase of apoptosis	672	4.399595e-15	8.615218840029762e-14	2.212385	123	0.002952402	979	0.03031251593156282	1.263934	26	26	0.001750135	
GO Biological Process	apoptotic nuclear changes	686	6.401663e-15	1.2279808078279883e-13	2.233458	119	0.002856388	1065	0.04454543905633803	1.263934	24	24	0.001615509	
GO Cellular Component	axon cytoplasm	66	6.22067e-34	1.6286845090909092e-32	2.303073	272	0.006528888	181	0.009333073113812153	1.232335	39	40	0.002625202	
GO Cellular Component	telomerase holoenzyme complex	201	5.003187e-11	4.3012473313432836e-10	2.177245	89	0.002136291	235	0.04237693521702128	1.263934	22	22	0.001480883	
GO Molecular Function	rRNA binding	60	1.563685e-29	1.1003130116666667e-27	2.470696	204	0.004896666	142	0.01776235836056338	1.200737	57	60	0.003836834	
GO Molecular Function	snRNA binding	144	8.396038e-13	2.4616716969444445e-11	2.056956	121	0.002904395	162	0.03887956402469136	1.230672	37	38	0.002490576	
Mouse Phenotype Single KO	increased squamous cell carcinoma incidence	134	6.189399e-22	4.229576615149253e-20	2.257429	178	0.004272581	592	0.03488295731587838	1.263934	26	26	0.001750135