# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	17	5.891801e-38	4.560600550529412e-35	2.719241	222	0.01877696	265	0.0017626644366792454	1.433354	71	113	0.008625926	
GO Biological Process	liver regeneration	20	2.267103e-36	1.49164041885e-33	3.834577	130	0.01099552	439	0.026457935024145788	1.629467	25	35	0.003037298	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	21	3.086829e-36	1.934265848142857e-33	2.923574	188	0.01590121	195	0.0001426032732153846	1.488615	77	118	0.009354878	
GO Biological Process	mRNA catabolic process	28	4.397459e-34	2.0666486778928573e-31	2.165571	309	0.0261355	187	0.00008325685226203208	1.370894	128	213	0.01555097	
GO Biological Process	rRNA processing	29	1.32433e-33	6.009261541379311e-31	2.110373	323	0.02731963	106	2.592407416226415e-8	1.448415	160	252	0.01943871	
GO Biological Process	nuclear-transcribed mRNA catabolic process	30	1.332541e-33	5.844969006333334e-31	2.224322	287	0.02427472	177	0.000049937988670056495	1.3941	121	198	0.01470052	
GO Biological Process	rRNA metabolic process	31	3.490608e-33	1.4817067958709676e-30	2.082268	329	0.02782712	100	2.2270212645999995e-8	1.4445	164	259	0.01992468	
GO Biological Process	regulation of DNA-templated transcription in response to stress	34	1.332996e-32	5.159086577647059e-30	2.458063	227	0.01919986	240	0.0010146044082083334	1.437765	75	119	0.009111894	
GO Biological Process	regulation of cellular amino acid metabolic process	51	2.465852e-28	6.362381660392157e-26	3.575733	109	0.009219318	372	0.010530281045430108	1.520836	40	60	0.004859677	
GO Biological Process	macromolecular complex disassembly	57	1.218677e-26	2.813433446140351e-24	2.018014	282	0.02385181	102	2.4810584946078428e-8	1.516855	127	191	0.01542947	
GO Biological Process	viral transcription	64	2.095821e-25	4.30920445921875e-23	2.523045	166	0.01404043	162	0.00001203182605308642	1.554483	77	113	0.009354878	
GO Biological Process	mitochondrial translational termination	65	2.756942e-25	5.58132304276923e-23	2.916509	129	0.01091094	131	4.567114220076336e-7	1.704385	65	87	0.007896975	
GO Biological Process	protein complex disassembly	67	3.610496e-25	7.09112192e-23	2.100124	241	0.020384	138	0.0000011753838116666666	1.506488	105	159	0.01275665	
GO Biological Process	multi-organism metabolic process	68	6.008883e-25	1.1628072264264706e-22	2.232292	208	0.01759283	140	0.0000016920716333571427	1.520836	98	147	0.01190621	
GO Biological Process	viral gene expression	71	7.972497e-25	1.4776068735633802e-22	2.436523	173	0.0146325	180	0.000057080167138333334	1.490898	83	127	0.01008383	
GO Biological Process	cellular protein complex disassembly	75	2.299331e-24	4.0342528838666666e-22	2.273686	195	0.01649328	133	8.66144871150376e-7	1.575151	87	126	0.0105698	
GO Biological Process	mitochondrial translational elongation	76	5.16967e-24	8.951011517105263e-22	2.872928	125	0.01057261	148	0.000004290270558716217	1.663973	62	85	0.007532499	
GO Biological Process	translational elongation	79	2.030861e-23	3.38279745556962e-21	2.47266	158	0.01336378	175	0.000047350127452571425	1.527625	75	112	0.009111894	
GO Biological Process	translational termination	83	5.56024e-23	8.815325079518071e-21	2.622504	139	0.01175675	130	3.261822553076923e-7	1.680924	70	95	0.008504434	
GO Biological Process	cotranslational protein targeting to membrane	85	1.17206e-22	1.8144867694117647e-20	2.60006	139	0.01175675	298	0.0035767305684899324	1.443242	62	98	0.007532499	
GO Cellular Component	ribosomal subunit	34	5.950535e-34	3.0242719058823527e-32	2.4003	248	0.02097606	40	6.13740672e-9	1.529057	124	185	0.015065	
GO Cellular Component	ribosome	37	6.435023e-32	3.0053296605405408e-30	2.101892	309	0.0261355	38	5.724718484210526e-9	1.469282	152	236	0.01846677	
GO Cellular Component	mitochondrial ribosome	38	1.55036e-28	7.050058105263158e-27	3.285837	123	0.01040345	46	1.3130887930434782e-7	1.71765	64	85	0.007775483	
GO Cellular Component	large ribosomal subunit	40	4.704281e-24	2.0322493919999997e-22	2.519309	157	0.0132792	44	2.5031627345454545e-8	1.64647	83	115	0.01008383	
GO Cellular Component	mitochondrial large ribosomal subunit	41	4.307011e-23	1.815247562926829e-21	3.730443	83	0.007020215	48	6.2946324e-7	1.87868	42	51	0.005102661	
GO Cellular Component	catalytic step 2 spliceosome	47	7.187185e-19	2.6424373787234042e-17	2.26586	149	0.01260255	64	0.00035816148	1.497073	63	96	0.007653991	
GO Cellular Component	proteasome complex	49	3.796672e-17	1.3389080032653064e-15	2.527195	108	0.009134737	75	0.0014277362687999998	1.543201	46	68	0.005588628	
GO Cellular Component	endopeptidase complex	50	3.941161e-17	1.3620652416e-15	2.525768	108	0.009134737	78	0.0023737912615384616	1.520836	46	69	0.005588628	
GO Cellular Component	peptidase complex	63	8.888965e-13	2.4381161142857144e-11	2.058239	120	0.01014971	113	0.0215982872920354	1.373937	53	88	0.006439072	
GO Cellular Component	nuclear ubiquitin ligase complex	83	4.772215e-10	9.93540665060241e-9	2.567425	57	0.004821111	89	0.00438730851235955	1.653909	29	40	0.003523266	
GO Cellular Component	endoribonuclease complex	86	6.775955e-10	1.3614942139534884e-8	2.73872	50	0.004229045	119	0.0251916407394958	1.651942	21	29	0.00255133	
GO Cellular Component	ciliary tip	87	8.798145e-10	1.747493627586207e-8	2.066741	87	0.007358538	77	0.0021777734898701297	1.659094	32	44	0.003887741	
GO Cellular Component	INO80-type complex	94	2.853864e-9	5.246252119148936e-8	3.432205	33	0.00279117	84	0.0033066390857142856	1.884514	19	23	0.002308346	
GO Cellular Component	spliceosomal snRNP complex	100	7.314102e-9	1.2638768256e-7	2.14194	71	0.006005244	104	0.01355839643076923	1.471777	40	62	0.004859677	
GO Cellular Component	Ino80 complex	110	1.863124e-8	2.9267984290909093e-7	3.920094	25	0.002114523	73	0.0009398942334246576	2.138675	15	16	0.001822379	
GO Cellular Component	proteasome core complex, beta-subunit complex	119	4.414317e-8	6.410033425210084e-7	5.067452	18	0.001522456	118	0.02531701586440678	2.073867	10	11	0.001214919	
GO Cellular Component	Mre11 complex	122	5.789737e-8	8.200545521311476e-7	5.281823	17	0.001437875	143	0.037529247776223774	2.281254	7	7	0.0008504434	
GO Cellular Component	intraciliary transport particle	123	7.817542e-8	0.0000010982693151219513	2.508624	44	0.00372156	145	0.04622939851034483	1.568362	22	32	0.002672822	
GO Cellular Component	proteasome accessory complex	137	4.11863e-7	0.0000051948851386861315	2.663691	35	0.002960332	124	0.027230729806451612	1.71094	18	24	0.002186855	
GO Cellular Component	proton-transporting ATP synthase complex	140	5.389221e-7	0.000006651838491428571	2.828248	31	0.002622008	99	0.007908747054545454	1.805993	19	24	0.002308346	
GO Molecular Function	structural constituent of ribosome	8	2.118801e-28	1.1181972277499998e-25	2.320405	220	0.0186078	16	9.05619263875e-7	1.520836	108	162	0.01312113	
GO Molecular Function	ribonuclease activity	12	5.528763e-18	1.9452031154999997e-15	2.218076	148	0.01251797	77	0.030888618064935067	1.382578	60	99	0.007289515	
GO Molecular Function	endoribonuclease activity	18	6.030384e-15	1.4144600693333334e-12	2.522504	93	0.007866024	82	0.03334857398780488	1.507257	37	56	0.004495201	
Human Phenotype	Increased serum lactate	12	1.605505e-19	8.927945720833333e-17	2.321273	147	0.01243339	74	0.0033555640395945946	1.460002	64	100	0.007775483	
Human Phenotype	Exercise intolerance	17	1.372641e-17	5.388019642941176e-15	2.649737	102	0.008627252	143	0.04797476353846154	1.433931	44	70	0.005345645	
Human Phenotype	Lipid accumulation in hepatocytes	34	3.364709e-12	6.603736222647058e-10	2.042232	116	0.009811385	83	0.006137490142048193	1.520836	48	72	0.005831612	
Human Phenotype	Glycosuria	42	1.32408e-11	2.1037109142857147e-9	2.668617	63	0.005328597	91	0.0076862547186813185	1.80927	23	29	0.002794314	
Human Phenotype	Dysphonia	61	4.963098e-10	5.429303762950819e-8	2.671919	53	0.004482788	96	0.011173062668749999	1.884514	19	23	0.002308346	
Human Phenotype	Delayed epiphyseal ossification	99	1.864328e-8	0.0000012566323983838382	4.215944	23	0.001945361	134	0.040916998435074625	2.091149	11	12	0.001336411	
Mouse Phenotype	absent embryonic cilia	338	7.638256e-7	0.00002160632118816568	2.836935	30	0.002537427	181	0.037381212190607735	1.901045	15	18	0.001822379