# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	liver regeneration	15	6.744688e-24	5.916889959466667e-21	4.454709	70	0.01277372	223	0.008089816848878923	2.140378	20	35	0.003989627	
GO Biological Process	rRNA processing	27	3.909455e-20	1.9053525312962965e-17	2.255401	160	0.02919708	125	0.000244428319728	1.501237	101	252	0.02014762	
GO Biological Process	rRNA metabolic process	28	1.344121e-19	6.316888656785714e-17	2.212091	162	0.02956204	145	0.00047227369669655174	1.475125	102	259	0.0203471	
GO Biological Process	protein targeting to ER	40	5.033007e-18	1.6557334778249998e-15	3.102659	81	0.01478102	168	0.0011241138411904762	1.74303	47	101	0.009375623	
GO Biological Process	establishment of protein localization to endoplasmic reticulum	47	9.265433e-17	2.5941241031276592e-14	2.853805	85	0.01551095	159	0.0007150020445345912	1.747975	49	105	0.009774586	
GO Biological Process	cotranslational protein targeting to membrane	48	9.492369e-17	2.6022934098125e-14	3.067109	76	0.01386861	165	0.0010628245169696968	1.758168	46	98	0.009176142	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	52	2.791905e-16	7.065130364423076e-14	2.81827	84	0.01532847	253	0.017051973123320158	1.555402	49	118	0.009774586	
GO Biological Process	protein localization to endoplasmic reticulum	54	3.721187e-16	9.067981432037038e-14	2.623594	94	0.01715328	191	0.0024967741919895287	1.631175	54	124	0.01077199	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	56	1.066837e-15	2.5068764433928573e-13	3.059431	71	0.0129562	227	0.009478978407048458	1.669262	41	92	0.008178735	
GO Biological Process	regulation of peroxisome proliferator activated receptor signaling pathway	59	1.648323e-15	3.676319043559322e-13	4.732665	41	0.007481752	284	0.03076810042640845	2.809246	9	12	0.001795332	
GO Biological Process	viral gene expression	65	2.99737e-15	6.068060281538462e-13	2.64357	87	0.01587591	173	0.0012869943168786126	1.65163	56	127	0.01117096	
GO Biological Process	multi-organism metabolic process	67	6.009654e-15	1.1803139848656716e-12	2.38491	103	0.01879562	157	0.000612775153	1.630764	64	147	0.01276681	
GO Biological Process	viral transcription	68	7.557393e-15	1.462466683632353e-12	2.68892	82	0.0149635	175	0.0013717422843428572	1.69052	51	113	0.01017355	
GO Biological Process	translational initiation	100	1.921022e-12	2.5278728498000003e-10	2.265791	93	0.0169708	232	0.011902945090086207	1.519219	58	143	0.01156992	
GO Biological Process	mitochondrial translational termination	132	7.01446e-11	6.992672662121211e-9	2.731548	56	0.01021898	312	0.04174581826378205	1.592982	37	87	0.00738081	
GO Biological Process	protein targeting to membrane	133	7.062226e-11	6.987355784511278e-9	2.153877	89	0.01624088	196	0.0033872655751530614	1.593304	57	134	0.01137044	
GO Biological Process	translational elongation	148	4.121419e-10	3.664442744662163e-8	2.329719	69	0.01259124	250	0.0169745941672	1.57184	47	112	0.009375623	
GO Biological Process	cellular protein complex disassembly	151	5.6715e-10	4.942468112582781e-8	2.113111	84	0.01532847	222	0.007659397484234234	1.575556	53	126	0.01057251	
GO Biological Process	translational termination	158	1.006661e-9	8.383957024683544e-8	2.442304	60	0.01094891	300	0.035143271962333335	1.577121	40	95	0.007979254	
GO Biological Process	negative regulation of cell cycle G2/M phase transition	173	3.249901e-9	2.4719911710404626e-7	2.257167	66	0.0120438	244	0.015025415393852458	1.646445	40	91	0.007979254	
GO Cellular Component	ribosomal subunit	31	1.029977e-16	5.741291148387097e-15	2.401369	115	0.0209854	40	0.0006137415359999999	1.538758	76	185	0.01516058	
GO Cellular Component	PcG protein complex	33	3.254705e-16	1.704281890909091e-14	3.134882	71	0.0129562	33	0.0002492766196363636	2.19854	27	46	0.005385996	
GO Cellular Component	ribosome	36	2.391938e-15	1.14813024e-13	2.083951	142	0.02591241	39	0.0005704912246153847	1.476044	93	236	0.01855177	
GO Cellular Component	endopeptidase complex	39	7.90638e-15	3.503134523076923e-13	3.178757	63	0.01149635	50	0.004691274624000001	1.791403	33	69	0.006582885	
GO Cellular Component	proteasome complex	41	2.489608e-14	1.0492786887804877e-12	3.130068	62	0.01131387	55	0.007793672727272728	1.762664	32	68	0.006383403	
GO Cellular Component	peptidase complex	43	4.796841e-13	1.927660755348837e-11	2.664367	72	0.01313869	57	0.00814877507368421	1.660009	39	88	0.007779773	
GO Cellular Component	large ribosomal subunit	45	3.712873e-12	1.425743232e-10	2.527271	73	0.01332117	41	0.001378952007804878	1.661119	51	115	0.01017355	
GO Cellular Component	mitochondrial large ribosomal subunit	49	9.67473e-11	3.411823151020408e-9	3.587824	37	0.006751825	66	0.014039638690909092	1.836108	25	51	0.004987034	
GO Cellular Component	mitochondrial ribosome	52	1.213351e-10	4.032058707692308e-9	2.881762	50	0.009124088	67	0.015030716561194028	1.630464	37	85	0.00738081	
GO Cellular Component	catalytic step 2 spliceosome	53	2.337188e-10	7.620114837735849e-9	2.329444	71	0.0129562	65	0.01301755835076923	1.59971	41	96	0.008178735	
GO Cellular Component	methyltransferase complex	65	6.293034e-8	0.0000016729788849230768	2.081315	66	0.0120438	68	0.015531556235294116	1.605283	39	91	0.007779773	
GO Cellular Component	Bcl-2 family protein complex	80	0.000001826876	0.0000394605216	4.925708	14	0.002554745	80	0.0421393104	3.210567	6	7	0.001196888	
GO Cellular Component	3M complex	103	0.00002143357	0.0003595845530097087	7.203928	8	0.001459854	76	0.03079302821052631	3.745661	5	5	0.0009974067	
GO Cellular Component	Holliday junction resolvase complex	104	0.00002250711	0.0003739642892307693	15.46017	5	0.0009124088	76	0.03079302821052631	3.745661	5	5	0.0009974067	
GO Molecular Function	structural constituent of ribosome	8	7.650983e-17	4.03780627825e-14	2.48036	109	0.01989051	28	0.0012394513337142857	1.595374	69	162	0.01376421	
GO Molecular Function	deoxyribonuclease activity	71	0.00000108152	0.00006431235830985916	2.158361	49	0.008941606	46	0.013573271086956521	1.768784	34	72	0.006782366	
GO Molecular Function	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	219	0.0008585718	0.016552009769863013	2.014826	26	0.004744526	50	0.015118889115999998	2.069971	21	38	0.004189108	
GO Molecular Function	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	249	0.001320312	0.022386976963855422	3.250437	10	0.001824818	39	0.007501591141538462	3.121384	10	12	0.001994813	
Mouse Phenotype Single KO	pale liver	23	5.185442e-19	2.064482278e-16	2.92248	94	0.01715328	65	0.00742202180123077	1.779189	38	80	0.007580291	
Mouse Phenotype Single KO	abnormal embryonic hematopoiesis	64	1.003419e-11	1.43567309109375e-9	2.28942	85	0.01551095	22	0.00002416675065954545	2.332204	33	53	0.006582885	
Mouse Phenotype Single KO	abnormal embryonic erythropoiesis	83	8.631655e-10	9.522899377710843e-8	2.854988	46	0.008394161	71	0.008618708979295774	2.324893	18	29	0.003590664	
Mouse Phenotype	extramedullary hematopoiesis	2	1.131252e-35	5.407950186e-32	2.615007	220	0.04014599	128	0.038053385032031255	1.434053	67	175	0.01336525	
Mouse Phenotype	dry eyes	39	6.831269e-16	1.6747118694615383e-13	4.35274	46	0.008394161	129	0.03915382179534884	2.575142	11	16	0.002194295	
Mouse Phenotype	pale liver	62	1.397991e-12	2.1558374114516128e-10	2.12104	109	0.01989051	84	0.010256415920357143	1.63447	48	110	0.009575105	
Mouse Phenotype	abnormal embryonic hematopoiesis	104	2.783407e-9	2.558860992980769e-7	2.020032	86	0.01569343	35	0.00041130875657142854	2.087746	34	61	0.006782366	
Mouse Phenotype	abnormal embryonic erythropoiesis	128	4.083748e-8	0.0000030503683303125	2.504336	46	0.008394161	104	0.02064568324903846	2.1749	18	31	0.003590664	
Mouse Phenotype	abnormal skin sebaceous gland morphology	173	7.079488e-7	0.00003912542472138729	2.069043	56	0.01021898	76	0.006766480727368422	2.295728	19	31	0.003790146	
Mouse Phenotype	abnormal Meibomian gland morphology	183	0.000001230684	0.00006429819521311476	2.093901	52	0.009489051	87	0.011103365134482759	2.397223	16	25	0.003191702	
Mouse Phenotype	pale lung	187	0.000001669732	0.00008537062915508021	4.632745	15	0.002737226	117	0.02952524238205128	3.745661	6	6	0.001196888