# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	cellular macromolecular complex assembly	35	2.145755e-44	8.067425727142856e-42	2.056638	431	0.1274771	112	0.000005786364773214286	1.421611	200	825	0.06246096	
GO Biological Process	translation	67	4.555824e-31	8.947774330746269e-29	2.586366	192	0.05678793	15	7.7310756716e-20	2.238465	142	372	0.04434728	
GO Biological Process	ncRNA metabolic process	80	1.737692e-28	2.8582861285e-26	2.238667	231	0.06832298	36	7.192654570833333e-14	1.817357	172	555	0.05371643	
GO Biological Process	ncRNA processing	82	6.546438e-28	1.0505436297804877e-25	2.511996	181	0.05353446	39	1.8167662932564103e-13	1.969524	133	396	0.04153654	
GO Biological Process	ribonucleoprotein complex biogenesis	83	7.842357e-28	1.2433442863012047e-25	2.276126	218	0.06447797	17	8.658691665294119e-20	2.10541	163	454	0.05090568	
GO Biological Process	ribosome biogenesis	85	1.607675e-27	2.488870038235294e-25	2.644217	163	0.04821059	22	1.5601208716818182e-16	2.214941	122	323	0.03810119	
GO Biological Process	rRNA metabolic process	95	8.944579e-26	1.2389654216947369e-23	2.899309	131	0.03874593	45	6.018356376666666e-12	2.150942	95	259	0.02966896	
GO Biological Process	rRNA processing	96	1.550231e-25	2.1249468467708333e-23	2.924484	128	0.03785862	47	7.05219927787234e-12	2.16415	93	252	0.02904435	
GO Biological Process	peptide biosynthetic process	98	1.954843e-25	2.6248754119387758e-23	2.314634	192	0.05678793	20	1.710419979e-17	2.124257	142	392	0.04434728	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	109	2.373321e-23	2.865186333853211e-21	4.078496	75	0.02218279	54	8.613637714814815e-11	2.683593	54	118	0.01686446	
GO Biological Process	translational initiation	115	4.858784e-22	5.559716404869565e-20	3.435512	87	0.02573203	55	1.2313692158e-10	2.501489	61	143	0.01905059	
GO Biological Process	mRNA catabolic process	116	7.460331e-22	8.462973761120691e-20	2.818346	115	0.03401361	50	1.53390594254e-11	2.257559	82	213	0.02560899	
GO Biological Process	nuclear-transcribed mRNA catabolic process	127	2.292404e-20	2.3752554516535433e-18	2.84569	105	0.0310559	44	5.162209905e-12	2.339736	79	198	0.02467208	
GO Biological Process	cotranslational protein targeting to membrane	129	4.464561e-20	4.5541983100000006e-18	4.120895	63	0.01863354	59	3.193479648135593e-10	2.812397	47	98	0.01467833	
GO Biological Process	translational elongation	135	7.270103e-20	7.08646558348148e-18	3.77606	69	0.02040816	86	2.4781135908139537e-7	2.408489	46	112	0.01436602	
GO Biological Process	RNA catabolic process	136	7.510046e-20	7.266521714264706e-18	2.561107	122	0.036084	51	6.493698159607843e-11	2.141265	88	241	0.02748282	
GO Biological Process	mitochondrial translational elongation	139	1.108287e-19	1.0492049376258994e-17	4.500755	56	0.01656315	100	0.0000012671352462099999	2.552629	37	85	0.01155528	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	141	1.573808e-19	1.468775849078014e-17	4.190531	60	0.01774623	68	7.176280001470588e-9	2.740852	43	92	0.01342911	
GO Biological Process	mitochondrial translation	143	1.956045e-19	1.7999717590909093e-17	3.89092	65	0.01922508	96	4.770048402604166e-7	2.411425	44	107	0.01374141	
GO Biological Process	protein targeting to ER	145	5.422757e-19	4.921245473310345e-17	3.911334	63	0.01863354	77	6.553352896103897e-8	2.554678	44	101	0.01374141	
GO Cellular Component	Golgi subcompartment	11	1.166924e-44	1.83313152e-42	2.720053	255	0.07542147	77	0.023048827012987015	1.416841	72	298	0.02248595	
GO Cellular Component	organelle subcompartment	12	6.702078e-43	9.65099232e-41	2.635708	258	0.07630878	90	0.04946851199999999	1.364613	74	318	0.02311056	
GO Cellular Component	ribonucleoprotein complex	13	2.017381e-41	2.6815648984615383e-39	2.155296	364	0.1076605	15	1.879456896e-23	1.851836	258	817	0.08057464	
GO Cellular Component	intracellular ribonucleoprotein complex	14	3.571304e-41	4.408009508571429e-39	2.152115	363	0.1073647	16	2.27788848e-23	1.851457	257	814	0.08026234	
GO Cellular Component	ribosomal subunit	18	1.766356e-34	1.6957017600000001e-32	3.959882	117	0.03460515	17	1.959374117647059e-17	2.66264	84	185	0.0262336	
GO Cellular Component	ribosome	19	8.188472e-34	7.447199797894736e-32	3.353927	141	0.04170364	18	4.4467891199999995e-17	2.435112	98	236	0.03060587	
GO Cellular Component	large ribosomal subunit	28	1.178113e-18	7.270640228571429e-17	3.703465	66	0.01952085	30	7.561105920000001e-8	2.396652	47	115	0.01467833	
GO Cellular Component	small ribosomal subunit	30	1.010846e-17	5.82247296e-16	4.334249	52	0.01538007	27	3.04497344e-10	3.094967	38	72	0.01186758	
GO Cellular Component	cytosolic ribosome	33	4.923609e-16	2.5781807127272728e-14	3.100063	71	0.0209997	26	3.151962387692308e-11	2.72264	52	112	0.01623985	
GO Cellular Component	mitochondrial ribosome	35	4.404319e-15	2.1744752091428574e-13	4.203741	45	0.01330967	41	0.00006146192546341463	2.276669	33	85	0.01030606	
GO Cellular Component	endopeptidase complex	41	5.551741e-12	2.3398557190243905e-10	3.516581	43	0.01271813	57	0.003070064842105263	2.124691	25	69	0.00780762	
GO Cellular Component	cytosolic large ribosomal subunit	42	6.421061e-12	2.641807954285714e-10	3.632668	41	0.01212659	35	0.000007509359725714285	2.69174	28	61	0.008744535	
GO Cellular Component	proteasome complex	44	1.953286e-11	7.671086836363636e-10	3.436741	42	0.01242236	63	0.006041233371428572	2.069699	24	68	0.007495315	
GO Cellular Component	peptidase complex	48	9.137176e-11	3.2893833599999997e-9	2.938956	49	0.01449275	55	0.002515100544	1.999141	30	88	0.009369144	
GO Cellular Component	spliceosomal complex	49	9.285463e-11	3.274546951836735e-9	2.157643	87	0.02573203	36	0.000013072272	1.89166	60	186	0.01873829	
GO Cellular Component	nuclear proteasome complex	51	2.551729e-10	8.64585825882353e-9	13.32401	12	0.003549246	49	0.0010013795265306122	5.131129	7	8	0.002186134	
GO Cellular Component	spliceosomal tri-snRNP complex	52	3.025117e-10	1.0052696492307692e-8	5.266385	23	0.006802721	37	0.000025237374616216214	3.437604	17	29	0.005309182	
GO Cellular Component	spliceosomal snRNP complex	58	1.920369e-9	5.721375227586207e-8	3.481331	33	0.009760426	46	0.0004606348382608696	2.364576	25	62	0.00780762	
GO Cellular Component	cytosolic small ribosomal subunit	59	2.992346e-9	8.76402353898305e-8	3.679661	30	0.008873114	33	9.101700654545454e-7	3.198626	24	44	0.007495315	
GO Cellular Component	mitochondrial small ribosomal subunit	61	5.482007e-9	1.5529357534426228e-7	5.182516	20	0.00591541	53	0.0020327618173584905	2.932074	14	28	0.004372267	
GO Molecular Function	structural constituent of ribosome	10	1.578828e-31	6.665811816e-29	3.946457	107	0.03164744	6	6.786197924e-16	2.751081	76	162	0.02373517	
GO Molecular Function	ATP-dependent helicase activity	30	6.676245e-8	0.00000939570213	2.288327	53	0.01567584	12	0.00498711084	2.055474	34	97	0.01061836	
GO Molecular Function	mRNA 5'-UTR binding	43	0.000001537785	0.0001509890295348837	3.94334	18	0.005323869	22	0.01351008335	3.198626	12	22	0.003747658	
GO Molecular Function	ribonucleoprotein complex binding	55	0.000007593697	0.0005829197951636364	2.072526	45	0.01330967	21	0.010599095774285713	1.886726	37	115	0.01155528	
GO Molecular Function	RNA methyltransferase activity	72	0.00008088183	0.0047428206425	2.317098	27	0.007985803	16	0.0098068457675	2.325438	23	58	0.007183011	
Mouse Phenotype	spleen atrophy	323	0.001210743	0.035838742486068116	2.245972	19	0.005619639	6	0.0053715403045	3.383162	15	26	0.004684572