# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	18	1.288588e-85	9.420294162222222e-83	2.469309	615	0.01705113	319	0.0000026741336167711595	1.225794	109	113	0.007376827	
GO Biological Process	endoplasmic reticulum unfolded protein response	19	4.243246e-84	2.938782848105263e-81	2.497793	591	0.01638572	692	0.005449305436705203	1.159305	104	114	0.007038441	
GO Biological Process	cellular response to topologically incorrect protein	20	4.709066e-78	3.0983299747e-75	2.264874	666	0.01846512	545	0.0012172654478899082	1.16107	127	139	0.008595019	
GO Biological Process	regulation of DNA-templated transcription in response to stress	21	1.578945e-75	9.893970121428571e-73	2.271709	640	0.01774426	292	8.421259777739726e-7	1.228062	115	119	0.007782891	
GO Biological Process	regulation of intrinsic apoptotic signaling pathway	23	6.166431e-75	3.528002849086957e-72	2.076872	777	0.02154264	518	0.0008987515708880309	1.155997	141	155	0.009542501	
GO Biological Process	response to topologically incorrect protein	24	1.793967e-74	9.83617156375e-72	2.044634	802	0.02223578	476	0.0004801160671848739	1.150759	163	180	0.0110314	
GO Biological Process	cellular response to unfolded protein	28	6.376909e-73	2.99691948325e-70	2.28854	608	0.01685705	691	0.005278935662373372	1.155252	110	121	0.007444505	
GO Biological Process	response to unfolded protein	34	4.867192e-68	1.8837464567058824e-65	2.037499	738	0.02046135	534	0.0011276762760861424	1.151642	145	160	0.009813211	
GO Biological Process	negative regulation of intrinsic apoptotic signaling pathway	35	3.359974e-67	1.263254224742857e-64	2.315282	546	0.01513807	674	0.004741494222700296	1.176145	87	94	0.005887926	
GO Biological Process	liver regeneration	54	9.944667e-57	2.4233680195e-54	2.920026	302	0.008373073	953	0.03274327872927597	1.234469	34	35	0.002301029	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to hypoxia	75	1.950824e-46	3.422785735466667e-44	2.267334	390	0.01081291	466	0.000366735682360515	1.221901	75	78	0.005075799	
GO Biological Process	regulation of nuclease activity	78	3.686075e-45	6.21859755448718e-43	3.33497	196	0.00543418	922	0.027967399298264643	1.270777	26	26	0.00175961	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	88	4.045948e-43	6.050071560454545e-41	2.12568	417	0.01156149	333	0.000005864258954354354	1.21693	113	118	0.007647537	
GO Biological Process	regulation of mitochondrial membrane permeability	115	3.849417e-39	4.40473724373913e-37	2.056604	408	0.01131197	521	0.0009022171577927063	1.218553	70	73	0.004737412	
GO Biological Process	platelet-derived growth factor receptor signaling pathway	138	6.831534e-37	6.514214196086957e-35	2.13434	351	0.009731618	714	0.006728618746358543	1.270777	33	33	0.002233351	
GO Biological Process	translational elongation	139	1.231391e-36	1.1657463430935253e-34	2.026329	395	0.01095154	281	4.83908878683274e-7	1.236738	109	112	0.007376827	
GO Biological Process	cotranslational protein targeting to membrane	140	1.431747e-36	1.3457399123571428e-34	2.133798	348	0.009648442	299	9.896201744481606e-7	1.244843	96	98	0.006497022	
GO Biological Process	protein targeting to ER	156	2.533661e-34	2.1372080191666667e-32	2.060206	354	0.009814794	284	5.361106336619719e-7	1.245613	99	101	0.006700054	
GO Biological Process	mitochondrial translational termination	164	1.225055e-33	9.829572405487805e-32	2.201079	297	0.008234446	240	4.5863715167083335e-8	1.270777	87	87	0.005887926	
GO Biological Process	mitochondrial translational elongation	167	2.068758e-33	1.6301069773652694e-31	2.207436	293	0.008123544	251	7.099406323107571e-8	1.270777	85	85	0.005752572	
GO Cellular Component	mitochondrial ribosome	40	1.571383e-40	6.78837456e-39	2.478181	283	0.00784629	72	7.8479928e-7	1.255827	84	85	0.005684894	
GO Cellular Component	endopeptidase complex	61	6.431814e-26	1.8219958347540982e-24	2.046852	267	0.007402684	148	0.0009281838745945946	1.215526	66	69	0.004466703	
GO Cellular Component	proteasome complex	66	5.164964e-25	1.3522814836363638e-23	2.024998	264	0.007319508	151	0.0011095716874172186	1.214713	65	68	0.004399025	
GO Cellular Component	mitochondrial large ribosomal subunit	75	1.551124e-23	3.573789696e-22	2.430927	165	0.004574692	113	0.00007394833784070796	1.270777	51	51	0.003451543	
GO Cellular Component	nuclear ubiquitin ligase complex	86	2.492992e-21	5.009174623255814e-20	2.347608	159	0.00440834	145	0.0008100465964137931	1.270777	40	40	0.002707093	
GO Cellular Component	MLL1 complex	137	7.937848e-15	1.0012117769343066e-13	2.234584	118	0.003271598	172	0.009582068427906976	1.270777	29	29	0.001962642	
GO Cellular Component	INO80-type complex	209	1.754777e-9	1.4508395483253588e-8	2.284229	67	0.001857602	211	0.032967111582938385	1.270777	23	23	0.001556578	
GO Molecular Function	unfolded protein binding	11	1.192007e-39	4.5751395945454545e-37	2.142926	375	0.01039703	110	0.004198352961818182	1.174869	98	106	0.006632377	
GO Molecular Function	rRNA binding	19	3.161819e-29	7.025894641052633e-27	2.588025	185	0.0051292	126	0.01554439876190476	1.207238	57	60	0.003857607	
GO Molecular Function	cyclin-dependent protein serine/threonine kinase regulator activity	62	5.039201e-15	3.431533326129032e-13	2.018988	152	0.004214262	145	0.027771171692413794	1.270777	29	29	0.001962642	
Human Phenotype	Abnormal CSF metabolite level	22	2.763115e-24	8.381030179545455e-22	2.130987	226	0.006265942	128	0.00001407607311953125	1.270777	63	63	0.004263671	
Human Phenotype	Increased CSF lactate	47	9.972697e-19	1.4159107889574467e-16	2.019911	194	0.005378729	149	0.000040247375451677854	1.270777	58	58	0.003925284