# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	ncRNA metabolic process	2	1.329971e-28	8.7505441945e-25	2.147344	255	0.06553585	33	6.368018919696969e-9	1.636891	163	555	0.04838231	
GO Biological Process	rRNA processing	11	1.310771e-19	1.568039599e-16	2.501461	126	0.03238242	66	0.0000011896154695454546	1.835704	83	252	0.02463639	
GO Biological Process	ncRNA processing	13	3.107838e-19	3.145849249384616e-16	2.110388	175	0.04497558	62	8.686372633064515e-7	1.66078	118	396	0.03502523	
GO Biological Process	rRNA metabolic process	14	5.962681e-19	5.604494234214286e-16	2.442367	127	0.03263942	69	0.0000020727942373913043	1.80761	84	259	0.02493321	
GO Biological Process	ribosome biogenesis	21	4.527628e-16	2.837097945333333e-13	2.086196	148	0.03803649	91	0.00000922596433175824	1.673765	97	323	0.02879193	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	23	6.179166e-16	3.5352889301739134e-13	2.903058	78	0.02004626	178	0.0032740227771910113	1.874262	38	113	0.01127931	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to hypoxia	27	1.55314e-14	7.56954417037037e-12	3.233426	60	0.0154202	148	0.0013610415938513512	2.14364	30	78	0.00890472	
GO Biological Process	regulation of DNA-templated transcription in response to stress	32	1.150586e-13	4.7314253668749995e-11	2.599326	79	0.02030326	196	0.004533166736836735	1.826597	39	119	0.01157614	
GO Biological Process	macromolecular complex disassembly	39	5.155364e-13	1.739472689128205e-10	2.217899	102	0.02621434	202	0.004905048518910891	1.634105	56	191	0.01662214	
GO Biological Process	citrate transport	44	1.506402e-12	4.5051690722727275e-10	17.64049	13	0.003341043	304	0.044793365858552626	5.573464	4	4	0.001187296	
GO Biological Process	protein complex disassembly	47	3.864676e-12	1.0820270528510638e-9	2.303635	87	0.02235929	235	0.012413433458297872	1.647502	47	159	0.01395073	
GO Biological Process	nucleoside triphosphate catabolic process	48	7.110161e-12	1.9492210124791668e-9	7.181507	21	0.00539707	238	0.014631011077731093	3.715643	8	12	0.002374592	
GO Biological Process	protein refolding	53	1.875454e-11	4.656433808679245e-9	8.383263	18	0.00462606	247	0.01941360588825911	2.919433	11	21	0.003265064	
GO Biological Process	multi-organism metabolic process	54	1.972651e-11	4.807058242407408e-9	2.413159	74	0.01901825	131	0.0005019076649389313	1.857821	49	147	0.01454438	
GO Biological Process	regulation of hematopoietic progenitor cell differentiation	61	4.049618e-11	8.735889059344262e-9	2.712034	58	0.01490619	263	0.026087337239923958	1.726294	35	113	0.01038884	
GO Biological Process	mRNA catabolic process	62	8.273665e-11	1.7560186731451612e-8	2.065628	97	0.02492932	175	0.003056701854171429	1.622323	62	213	0.01840309	
GO Biological Process	mitochondrial membrane organization	68	2.23878e-10	4.332368532352941e-8	2.213209	79	0.02030326	225	0.010614353519111113	1.752944	39	124	0.01157614	
GO Biological Process	protein targeting to ER	71	3.624654e-10	6.717862251549296e-8	2.751303	51	0.01310717	177	0.003206657977740113	1.931398	35	101	0.01038884	
GO Biological Process	nuclear-transcribed mRNA catabolic process	74	5.202911e-10	9.252041330945946e-8	2.072358	88	0.02261629	211	0.007054003561611374	1.604482	57	198	0.01691897	
GO Biological Process	regulation of hematopoietic stem cell differentiation	77	6.951789e-10	1.1880336552077922e-7	2.697501	51	0.01310717	293	0.03750233710614334	1.731562	32	103	0.009498367	
GO Cellular Component	catalytic step 2 spliceosome	29	3.507789e-14	2.0901584110344827e-12	3.003492	65	0.01670522	31	0.000002726037058064516	2.322277	40	96	0.01187296	
GO Cellular Component	mitochondrial membrane part	35	9.113089e-12	4.4992622262857136e-10	2.125705	100	0.02570033	75	0.017561608704	1.498526	57	212	0.01691897	
GO Cellular Component	spliceosomal complex	40	4.469008e-11	1.930611456e-9	2.090336	97	0.02492932	40	0.0000683545824	1.797892	60	186	0.01780944	
GO Cellular Component	PcG protein complex	42	7.874337e-10	3.239727222857143e-8	2.860487	46	0.01182215	69	0.014740000278260867	2.180921	18	46	0.005342832	
GO Cellular Component	peptidase complex	43	1.125909e-9	4.5245831441860464e-8	2.657976	51	0.01310717	42	0.00015547947428571428	2.153384	34	88	0.01009202	
GO Cellular Component	preribosome	45	2.174078e-9	8.34845952e-8	2.842589	44	0.01130815	66	0.005088666763636364	1.980046	27	76	0.008014248	
GO Cellular Component	ribosomal subunit	48	3.639594e-9	1.31025384e-7	2.146857	73	0.01876124	61	0.003225739750819672	1.626849	54	185	0.0160285	
GO Cellular Component	endopeptidase complex	49	3.818339e-9	1.3465489371428572e-7	2.913533	41	0.01053714	45	0.00034186460159999995	2.261696	28	69	0.008311072	
GO Cellular Component	proteasome complex	55	3.236136e-8	0.0000010167350923636363	2.772975	39	0.01002313	48	0.0007389846	2.212993	27	68	0.008014248	
GO Cellular Component	large ribosomal subunit	57	5.953996e-8	0.000001805000892631579	2.389155	49	0.01259316	64	0.0042421509	1.793201	37	115	0.01098249	
GO Cellular Component	centriolar satellite	71	0.000001696092	0.00004127953487323944	3.592264	20	0.005140067	78	0.019152420923076924	2.572368	12	26	0.003561888	
GO Cellular Component	proteasome core complex	73	0.000001770665	0.00004191382356164383	4.937364	14	0.003598047	88	0.029875293818181815	2.554504	11	24	0.003265064	
GO Cellular Component	spliceosomal snRNP complex	83	0.00001047952	0.00021817603084337348	2.56669	28	0.007196094	74	0.017514193037837838	1.977681	22	62	0.006530128	
GO Cellular Component	U12-type spliceosomal complex	90	0.00002551831	0.000489951552	3.482379	16	0.004112053	78	0.019152420923076924	2.572368	12	26	0.003561888	
GO Cellular Component	Cajal body	92	0.00003454928	0.0006489256069565217	2.244593	32	0.008224107	80	0.01948090824	2.026714	20	55	0.00593648	
GO Cellular Component	small nuclear ribonucleoprotein complex	103	0.00009813096	0.0016463135813592233	2.214102	29	0.007453097	89	0.02969527226966292	1.857821	23	69	0.006826952	
GO Cellular Component	U2 snRNP	104	0.0001001154	0.001663455876923077	3.852268	12	0.00308404	71	0.015732395898591548	2.933402	10	19	0.00296824	
GO Cellular Component	LUBAC complex	124	0.0002419097	0.003371128722580645	4.484976	9	0.00231303	49	0.0011722191281632653	5.573464	6	6	0.001780944	
GO Cellular Component	U2-type spliceosomal complex	151	0.0008403046	0.009616200985430465	2.211623	21	0.00539707	76	0.01746661035789474	2.322277	15	36	0.00445236	
GO Cellular Component	Lewy body	170	0.001363296	0.013857502870588234	3.860445	8	0.002056027	72	0.0160144344	4.180098	6	8	0.001780944	
GO Molecular Function	heat shock protein binding	17	7.333008e-10	1.8211741044705882e-7	2.277433	70	0.01799023	10	0.00001213409133	2.282466	43	105	0.01276343	
GO Molecular Function	structural constituent of ribosome	19	3.071041e-9	6.824176369473684e-7	2.211346	69	0.01773323	22	0.01697619949909091	1.685801	49	162	0.01454438	
GO Molecular Function	Hsp70 protein binding	60	0.00001788522	0.0012585233140000002	2.593179	26	0.006682087	31	0.04240108294193548	2.410147	16	37	0.004749184	
GO Molecular Function	ubiquitin-protein transferase regulator activity	100	0.0001852996	0.007823349112	2.633968	19	0.004883063	19	0.005768220837894737	3.606359	11	17	0.003265064	
Human Phenotype	Increased serum lactate	9	8.921177e-10	6.614557124555556e-7	2.59101	54	0.01387818	14	0.04060287421642857	1.894978	34	100	0.01009202