# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	liver regeneration	1	2.839866e-42	3.7369796694000003e-38	6.310796	92	0.01809599	287	0.009463966555052265	2.254142	18	35	0.004201681	
GO Biological Process	endoplasmic reticulum unfolded protein response	7	1.910961e-31	3.592333685571429e-28	3.598046	120	0.02360346	404	0.03190693347475248	1.576361	41	114	0.009570495	
GO Biological Process	cellular response to unfolded protein	19	3.548715e-28	2.4577652992105263e-25	3.257852	122	0.02399685	405	0.032152015032345674	1.557614	43	121	0.01003735	
GO Biological Process	negative regulation of intrinsic apoptotic signaling pathway	30	4.445532e-26	1.9499585196e-23	3.309181	110	0.02163651	418	0.03483492664354067	1.631988	35	94	0.008169935	
GO Biological Process	response to endoplasmic reticulum stress	40	3.992774e-23	1.3135228266500002e-20	2.207124	194	0.03815893	231	0.004031625367662338	1.472993	82	244	0.01914099	
GO Biological Process	regulation of intrinsic apoptotic signaling pathway	41	6.292506e-23	2.019587474487805e-20	2.616883	138	0.02714398	258	0.0058230258127906975	1.583555	56	155	0.0130719	
GO Biological Process	animal organ regeneration	48	5.504009e-20	1.5089011339791666e-17	2.669729	115	0.02261998	247	0.004970799463927126	1.8398	34	81	0.007936508	
GO Biological Process	nuclear-transcribed mRNA catabolic process	51	1.160251e-18	2.9936750801960786e-16	2.379095	132	0.02596381	174	0.0007718487076436781	1.593838	72	198	0.01680672	
GO Biological Process	mitochondrial transport	54	8.72286e-18	2.125631754444444e-15	2.09844	164	0.03225806	145	0.00022074658108275864	1.577166	86	239	0.0200747	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	56	1.256725e-17	2.9530793348214287e-15	3.001625	83	0.01632573	201	0.0016246618594527363	1.745792	47	118	0.01097106	
GO Biological Process	negative regulation of response to endoplasmic reticulum stress	59	2.891971e-17	6.4500756591525426e-15	3.743488	60	0.01180173	453	0.04561243458498896	1.972374	18	40	0.004201681	
GO Biological Process	mRNA catabolic process	66	2.034011e-16	4.0553864771212124e-14	2.200239	135	0.02655389	220	0.002775062033	1.522751	74	213	0.01727358	
GO Biological Process	regulation of mitochondrial membrane permeability	75	6.239877e-16	1.0948072192399999e-13	2.860863	80	0.01573564	142	0.00019269835728169012	2.101464	35	73	0.008169935	
GO Biological Process	RNA catabolic process	79	2.459137e-15	4.0961751624050634e-13	2.052225	147	0.02891424	219	0.002614608577671233	1.491329	82	241	0.01914099	
GO Biological Process	protein targeting to ER	81	2.700863e-15	4.387735335432099e-13	2.972737	72	0.01416208	305	0.010916331044918032	1.692466	39	101	0.009103641	
GO Biological Process	cotranslational protein targeting to membrane	89	6.434521e-15	9.513692341460673e-13	3.00151	69	0.01357199	259	0.006095863564092664	1.744276	39	98	0.009103641	
GO Biological Process	protein localization to endoplasmic reticulum	97	1.350276e-14	1.831781637525773e-12	2.587273	86	0.01691581	221	0.00289861688561086	1.696666	48	124	0.01120448	
GO Biological Process	establishment of protein localization to endoplasmic reticulum	106	6.456496e-14	8.015191590943395e-12	2.714199	75	0.01475216	263	0.006693663080988593	1.711478	41	105	0.009570495	
GO Biological Process	macromolecular complex disassembly	110	1.18838e-13	1.4216265836363637e-11	2.080211	125	0.02458694	144	0.0002124655795277778	1.65225	72	191	0.01680672	
GO Biological Process	regulation of membrane permeability	115	1.692852e-13	1.9370643015652173e-11	2.547376	81	0.01593234	181	0.0009528351928176795	1.948024	36	81	0.008403361	
GO Cellular Component	ribosomal subunit	38	3.240407e-14	1.4735324463157895e-12	2.318319	103	0.02025964	41	0.0004964990751219513	1.611068	68	185	0.01587302	
GO Cellular Component	ribosome	42	1.795695e-13	7.388002285714286e-12	2.040628	129	0.02537372	32	0.0000359501112	1.615787	87	236	0.02030812	
GO Cellular Component	catalytic step 2 spliceosome	43	1.946479e-13	7.822129562790697e-12	2.652346	75	0.01475216	35	0.00007546600594285714	1.963243	43	96	0.01003735	
GO Cellular Component	mitochondrial ribosome	53	2.995593e-11	9.766763592452832e-10	3.044102	49	0.00963808	68	0.016589018541176472	1.701656	33	85	0.007703081	
GO Cellular Component	large ribosomal subunit	58	2.710111e-10	8.074261737931034e-9	2.42559	65	0.01278521	57	0.008756691536842106	1.638881	43	115	0.01003735	
GO Cellular Component	nuclear ubiquitin ligase complex	60	6.465011e-10	1.8619231680000003e-8	3.561426	34	0.006687648	63	0.01409117622857143	2.08195	19	40	0.004435107	
GO Cellular Component	U5 snRNP	87	2.875308e-7	0.000005710956579310345	4.042394	20	0.00393391	77	0.027505518545454542	2.390756	12	22	0.00280112	
GO Cellular Component	spliceosomal snRNP complex	90	3.507754e-7	0.00000673488768	2.595809	37	0.007277734	56	0.007132810628571428	1.908749	27	62	0.006302521	
GO Cellular Component	preribosome	105	0.000003021431	0.0000497241216	2.175554	44	0.008654603	85	0.03748771990588235	1.672481	29	76	0.006769374	
GO Cellular Component	methylosome	115	0.00001186186	0.00017823733982608696	5.286137	11	0.002163651	78	0.03255921969230769	2.922035	8	12	0.001867414	
GO Cellular Component	small nuclear ribonucleoprotein complex	121	0.00001991124	0.0002843522538842975	2.162007	37	0.007277734	83	0.0353593353253012	1.715108	27	69	0.006302521	
GO Cellular Component	U4 snRNP	147	0.0001229837	0.001445685942857143	4.920623	9	0.00177026	86	0.0397839248372093	3.068137	7	10	0.001633987	
GO Cellular Component	Cul4-RING E3 ubiquitin ligase complex	193	0.0006910931	0.006187610760621761	2.247813	21	0.004130606	88	0.0455317789090909	2.054556	15	32	0.003501401	
GO Molecular Function	cadherin binding	3	3.679634e-26	5.1784715826666673e-23	2.006735	275	0.05409127	10	0.000015678941638	1.600391	111	304	0.02591036	
GO Molecular Function	glucocorticoid receptor binding	18	3.009409e-15	7.058735998888889e-13	4.021123	48	0.009441385	60	0.033580380666666666	3.034421	9	13	0.00210084	
GO Molecular Function	structural constituent of ribosome	23	9.849637e-14	1.8080507571304348e-11	2.354694	96	0.01888277	25	0.0023345093024	1.650409	61	162	0.01423903	
GO Molecular Function	C4-dicarboxylate transmembrane transporter activity	24	1.711705e-13	3.011174379166667e-11	7.295677	24	0.004720692	69	0.04530694283478261	3.409041	7	9	0.001633987	
GO Molecular Function	steroid hormone receptor binding	26	9.155871e-13	1.4867725908461538e-10	2.118612	111	0.0218332	66	0.03863287365454546	1.693452	34	88	0.007936508	
GO Molecular Function	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	47	5.071111e-8	0.000004555368221702128	5.328186	17	0.003343824	61	0.03355732116393443	2.477378	13	23	0.003034547	
GO Molecular Function	endoribonuclease activity, producing 3'-phosphomonoesters	101	0.00001560871	0.0006524749863366337	5.69661	10	0.001966955	67	0.038614134734328356	3.187675	8	11	0.001867414	
GO Molecular Function	non-membrane spanning protein tyrosine phosphatase activity	244	0.001173923	0.02031271682786885	3.302991	10	0.001966955	49	0.01769117949387755	3.835172	7	8	0.001633987	
Human Phenotype	Bronchomalacia	394	0.001674069	0.028352950347715736	2.088552	21	0.004130606	70	0.045492700857142854	3.034421	9	13	0.00210084