# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of nitric-oxide synthase activity	108	0.000001368843	0.00016678337997222224	2.350461	40	0.009019166	573	0.015366117962478184	1.88925	22	43	0.00432645	
GO Biological Process	regulation of monooxygenase activity	114	0.00000191861	0.0002214648157017544	2.130677	48	0.010823	488	0.007486629686885246	1.846313	27	54	0.005309735	
GO Biological Process	positive regulation of cellular response to insulin stimulus	133	0.00000569913	0.0005638710651879699	2.6036	29	0.006538895	767	0.04557083510821382	1.978192	15	28	0.002949853	
GO Biological Process	regulation of mitophagy	224	0.00006688472	0.0039291787075	2.265728	29	0.006538895	786	0.049112150385496184	1.728463	22	47	0.00432645	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	245	0.00009916874	0.005326373263918367	3.239495	15	0.003382187	732	0.03759120024863388	2.685546	8	11	0.001573255	
GO Biological Process	negative regulation of transcription regulatory region DNA binding	397	0.0007187692	0.023824392702267	2.109689	24	0.005411499	607	0.018517327457001645	2.285911	13	21	0.002556539	
Human Phenotype	Distal sensory impairment	5	2.2397e-7	0.000298910362	2.017544	65	0.01465614	36	0.001346416029388889	1.825091	43	87	0.008456244	
Human Phenotype	Bone marrow hypocellularity	16	0.00001761877	0.007348128263125	2.492469	28	0.006313416	93	0.01098565944623656	2.215575	18	30	0.003539823	
Mouse Phenotype Single KO	abnormal embryonic hematopoiesis	14	2.007929e-7	0.00013133289895	2.063408	62	0.01397971	463	0.027050845987041036	1.741804	25	53	0.004916421	
Mouse Phenotype Single KO	increased thymocyte number	16	4.722336e-7	0.0002702651922	2.84261	31	0.006989853	220	0.0017329243733181818	2.373831	18	28	0.003539823	
Mouse Phenotype Single KO	abnormal white fat cell number	36	0.000006051716	0.0015393212058888888	2.833432	25	0.005636979	386	0.012247575274352333	2.46175	12	18	0.002359882	
Mouse Phenotype Single KO	delayed cellular replicative senescence	90	0.0001409555	0.014341439038888888	4.83	9	0.002029312	401	0.014850016509975061	3.231047	7	8	0.001376598	
Mouse Phenotype Single KO	small scala media	137	0.0004244033	0.028366868745255475	2.615821	17	0.003833145	313	0.005762149032907348	3.282334	8	9	0.001573255	
Mouse Phenotype	abnormal sublingual gland morphology	48	0.000004484468	0.00089324996975	3.494742	19	0.004284104	999	0.045780747759759766	2.46175	8	12	0.001573255	
Mouse Phenotype	abnormal sublingual duct morphology	55	0.000008006827	0.0013918776899454544	4.055977	15	0.003382187	576	0.006533331741145833	3.692625	6	6	0.001179941	
Mouse Phenotype	abnormal mismatch repair	64	0.00001751934	0.0026172251521875	4.635023	12	0.00270575	832	0.025706943393028845	2.872042	7	9	0.001376598	
Mouse Phenotype	ruffled hair	94	0.00005357739	0.005449504529680851	2.378012	27	0.006087937	1038	0.04932075930635838	1.793561	17	35	0.003343166	
Mouse Phenotype	absent type I pneumocytes	107	0.00007664974	0.006849048262990654	3.317596	15	0.003382187	807	0.025071856505576206	3.165107	6	7	0.001179941	
Mouse Phenotype	abnormal third pharyngeal arch morphology	111	0.00008260487	0.007115181640270271	2.060074	35	0.00789177	496	0.0036790226818548388	2.241951	17	28	0.003343166	
Mouse Phenotype	abnormal third pharyngeal arch artery morphology	123	0.000117243	0.00911349856097561	2.191018	29	0.006538895	679	0.012027563395581739	2.285911	13	21	0.002556539	
Mouse Phenotype	decreased carbon dioxide production	177	0.000328147	0.017725499813559323	2.279439	23	0.00518602	956	0.0413776577541841	1.909979	15	29	0.002949853	
Mouse Phenotype	cardiac ischemia	204	0.0004765077	0.022332794704411765	4.556225	8	0.001803833	749	0.018566172732977303	3.692625	5	5	0.0009832842	
Mouse Phenotype	abnormal salivary gland duct morphology	210	0.0005231676	0.023819073445714285	2.354394	20	0.004509583	942	0.03968508223248408	2.373831	9	14	0.001769912	
Mouse Phenotype	small scala media	230	0.0006835161	0.02841346709608696	2.428772	18	0.004058625	401	0.0014059057092269329	3.323363	9	10	0.001769912	
Mouse Phenotype	absent Harderian gland	286	0.001439224	0.048113358965034964	2.587898	14	0.003156708	450	0.002262744504	3.692625	7	7	0.001376598