# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of hematopoietic progenitor cell differentiation	8	6.526773e-16	1.0735725738375e-12	3.617225	57	0.01988141	148	0.0024193150475	1.995842	35	113	0.01201098	
GO Biological Process	regulation of hematopoietic stem cell differentiation	10	9.197027e-16	1.21023678293e-12	3.804529	53	0.01848622	145	0.0019192428725517243	2.064493	33	103	0.01132464	
GO Biological Process	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	22	2.25577e-12	1.3492580650000001e-9	3.757122	41	0.01430066	162	0.003766578549259259	2.237403	25	72	0.008579272	
GO Biological Process	regulation of RNA stability	23	5.243685e-12	3.0000717789130433e-9	2.366672	81	0.02825253	172	0.005503855032848838	1.772023	44	160	0.01509952	
GO Biological Process	anaphase-promoting complex-dependent catabolic process	25	7.240889e-12	3.81131433404e-9	3.366833	45	0.01569585	160	0.0034263445321875002	2.174755	27	80	0.009265614	
GO Biological Process	regulation of mRNA stability	29	1.064276e-11	4.829244097931035e-9	2.392132	77	0.02685734	195	0.011368849640000001	1.749619	41	151	0.01407001	
GO Biological Process	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	30	1.828942e-11	8.022349259333334e-9	3.381378	43	0.01499826	140	0.0013666476835	2.289216	27	76	0.009265614	
GO Biological Process	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	32	2.721266e-11	1.1190356029375e-8	3.595129	39	0.01360307	181	0.00771656119281768	2.178159	24	71	0.008236102	
GO Biological Process	negative regulation of ubiquitin protein ligase activity	36	4.196374e-11	1.533891262944444e-8	3.472704	40	0.01395187	193	0.01092334044507772	2.092117	25	77	0.008579272	
GO Biological Process	negative regulation of gene expression, epigenetic	42	8.25812e-11	2.5873476447619047e-8	3.02735	47	0.01639344	283	0.044899544910600706	1.75224	31	114	0.0106383	
GO Biological Process	RNA catabolic process	44	9.532309e-11	2.850810321159091e-8	2.153796	87	0.03034531	256	0.03008144315859375	1.524033	57	241	0.01956074	
GO Biological Process	positive regulation of ubiquitin protein ligase activity	46	9.806316e-11	2.8052459183478258e-8	3.200071	43	0.01499826	183	0.007771007901092896	2.071196	27	84	0.009265614	
GO Biological Process	regulation of ubiquitin protein ligase activity	49	1.450702e-10	3.895875024081633e-8	3.10887	44	0.01534705	208	0.01465520993221154	1.961132	28	92	0.009608785	
GO Biological Process	tumor necrosis factor-mediated signaling pathway	51	1.750008e-10	4.51536377882353e-8	2.68333	55	0.01918382	155	0.003081810633032258	1.912979	38	128	0.01304049	
GO Biological Process	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	56	2.225801e-10	5.230234885535715e-8	2.723823	53	0.01848622	157	0.003408281578343949	2.006064	33	106	0.01132464	
GO Biological Process	negative regulation of ubiquitin-protein transferase activity	59	4.698303e-10	1.0478808335084746e-7	3.136024	41	0.01430066	215	0.01737190587395349	1.994485	26	84	0.008922443	
GO Biological Process	DNA-templated transcription, termination	61	6.923767e-10	1.4936040975901641e-7	2.909014	45	0.01569585	282	0.04363720851737589	1.773501	30	109	0.01029513	
GO Biological Process	regulation of gene expression, epigenetic	73	2.237292e-9	4.0329486887671233e-7	2.003971	88	0.03069411	169	0.005167881901183432	1.61093	62	248	0.0212766	
GO Biological Process	antigen processing and presentation of peptide antigen via MHC class I	76	3.203456e-9	5.546615461052631e-7	3.07956	38	0.01325427	271	0.037058832237638374	1.882435	26	89	0.008922443	
GO Biological Process	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	91	1.07931e-8	0.0000015607297021978022	2.650171	45	0.01569585	173	0.00553407069450867	2.053493	29	91	0.009951956	
GO Cellular Component	endopeptidase complex	25	4.67207e-13	3.229334784e-11	3.954153	41	0.01430066	47	0.0007446371131914894	2.334681	25	69	0.008579272	
GO Cellular Component	peptidase complex	27	1.109231e-12	7.0990784e-11	3.395124	48	0.01674224	45	0.000490122624	2.196723	30	88	0.01029513	
GO Cellular Component	proteasome complex	28	1.849733e-12	1.1415495085714287e-10	3.85989	40	0.01395187	51	0.0016367494023529412	2.274254	24	68	0.008236102	
GO Cellular Component	catalytic step 2 spliceosome	33	1.939017e-10	1.0153398109090908e-8	2.947437	47	0.01639344	38	0.000058843129263157895	2.282151	34	96	0.01166781	
GO Cellular Component	U2 snRNP	41	3.198313e-9	1.3479719180487804e-7	6.970898	16	0.005580746	67	0.02780450005970149	3.052288	9	19	0.003088538	
GO Cellular Component	chromosome, telomeric region	43	5.117649e-9	2.0565808074418605e-7	2.387582	57	0.01988141	50	0.0016514627327999997	1.774917	46	167	0.01578586	
GO Cellular Component	nuclear chromosome, telomeric region	45	7.03173e-9	2.7001843199999996e-7	2.591859	48	0.01674224	53	0.0024742113690566043	1.85501	38	132	0.01304049	
GO Cellular Component	nucleosome	46	7.49712e-9	2.816309426086956e-7	3.284963	33	0.01151029	61	0.013459632786885247	1.841063	30	105	0.01029513	
GO Cellular Component	ribosome	49	2.191497e-8	7.728381257142857e-7	2.04774	73	0.02546216	55	0.003088342551272727	1.61093	59	236	0.02024708	
GO Cellular Component	mitochondrial ribosome	54	1.039329e-7	0.0000033258528	3.194765	29	0.0101151	75	0.04594666752	1.819403	24	85	0.008236102	
GO Cellular Component	ribosomal subunit	56	1.376632e-7	0.000004247893028571428	2.195213	55	0.01918382	77	0.04641443906493507	1.53256	44	185	0.01509952	
GO Cellular Component	DNA packaging complex	62	2.829629e-7	0.000007886449858064517	2.747913	34	0.01185909	64	0.018896274	1.78353	31	112	0.0106383	
GO Cellular Component	integral component of endoplasmic reticulum membrane	69	0.000001119468	0.00002803537252173913	2.079499	53	0.01848622	74	0.03696327437837838	1.646206	35	137	0.01201098	
GO Cellular Component	methyltransferase complex	72	0.000001776992	0.000042647808000000004	2.350776	39	0.01360307	52	0.0024177328615384614	2.053493	29	91	0.009951956	
GO Cellular Component	Sin3-type complex	175	0.002264259	0.022357940297142855	2.831218	11	0.003836763	70	0.03272975177142857	3.22186	8	16	0.002745367	
GO Molecular Function	unfolded protein binding	4	2.589751e-11	2.7334821804999998e-8	3.235063	45	0.01569585	13	0.0050467157369230775	2.066854	34	106	0.01166781	
GO Molecular Function	nuclease activity	14	4.5859e-9	0.0000013829764142857143	2.060135	79	0.02755494	25	0.019076617248	1.641325	54	212	0.01853123	
Mouse Phenotype	extramedullary hematopoiesis	2	3.383985e-14	1.61771402925e-10	2.317412	102	0.03557726	23	0.03265828089391304	1.730599	47	175	0.01612903