# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	ribonucleoprotein complex biogenesis	1	2.055443e-13	2.7047574437000002e-9	2.16533	109	0.06133934	47	0.0000013464104014042554	1.790276	98	454	0.04328622	
GO Biological Process	rRNA metabolic process	6	4.151882e-12	9.105769206333333e-9	2.695014	64	0.03601576	66	0.00007642328504545454	1.921327	60	259	0.02650177	
GO Biological Process	ribosome biogenesis	7	4.617937e-12	8.681061854714285e-9	2.407475	78	0.0438942	72	0.0001164727580361111	1.797402	70	323	0.03091873	
GO Biological Process	rRNA processing	8	8.936282e-12	1.4699066854749999e-8	2.695185	62	0.03489026	77	0.0001276982342948052	1.908874	58	252	0.02561837	
GO Biological Process	ncRNA processing	9	1.697314e-11	2.4816616584444445e-8	2.244487	85	0.04783343	94	0.0010222497755425532	1.633613	78	396	0.0344523	
GO Biological Process	ncRNA metabolic process	10	1.707175e-11	2.2464715825e-8	2.009841	109	0.06133934	100	0.0017454702914	1.509309	101	555	0.04461131	
GO Biological Process	regulation of gene expression, epigenetic	21	2.272103e-9	0.000001423743017952381	2.314673	63	0.03545301	156	0.026754170238461532	1.63868	49	248	0.02164311	
GO Biological Process	RNA splicing, via transesterification reactions	24	1.962272e-8	0.000010758973853333332	2.057217	72	0.04051773	48	0.0000034727560510416668	1.987039	69	288	0.03047703	
GO Biological Process	mRNA splicing, via spliceosome	26	3.758536e-8	0.00001902252893230769	2.034283	71	0.03995498	58	0.000010226510043620691	1.949754	67	285	0.02959364	
GO Biological Process	DNA conformation change	28	5.620587e-8	0.000026414751547500002	2.03627	69	0.03882949	122	0.00549508730352459	1.682358	57	281	0.02517668	
GO Biological Process	mRNA catabolic process	30	1.92094e-7	0.00008425883153333334	2.284811	49	0.02757456	106	0.003214731285849057	1.830071	47	213	0.02075972	
GO Biological Process	RNA catabolic process	31	2.764191e-7	0.00011733544957741935	2.156847	54	0.03038829	115	0.0045115597172173914	1.755104	51	241	0.0225265	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	32	3.532503e-7	0.000145263146803125	3.000506	29	0.01631964	139	0.01169946809496403	2.038289	29	118	0.01280919	
GO Biological Process	gene silencing	33	5.754199e-7	0.00022945304436666666	2.367244	42	0.02363534	160	0.0310555360775	1.750898	38	180	0.01678445	
GO Biological Process	nuclear-transcribed mRNA catabolic process	38	0.000002207584	0.0007644631014736841	2.2173	43	0.02419809	158	0.028972395168987343	1.717388	41	198	0.01810954	
GO Biological Process	negative regulation of translation	41	0.000003441098	0.0011044245995609756	2.113272	46	0.02588633	71	0.00010791655125633804	2.261926	39	143	0.01722615	
GO Biological Process	negative regulation of telomere maintenance	88	0.00006205746	0.009279705865227273	3.220761	16	0.009003939	145	0.015636803399310343	2.994957	13	36	0.005742049	
GO Biological Process	gene silencing by miRNA	91	0.00007553097	0.010922110266263737	3.036005	17	0.009566685	108	0.003464086036759259	3.015901	16	44	0.007067138	
GO Biological Process	DNA duplex unwinding	102	0.0001144773	0.014768694026470588	2.453054	23	0.01294316	155	0.024786182034193548	2.272254	20	73	0.008833922	
GO Biological Process	posttranscriptional gene silencing by RNA	112	0.0001722741	0.020240668588392855	2.731245	18	0.01012943	125	0.00616409879344	2.764576	17	51	0.007508834	
GO Cellular Component	protein-DNA complex	25	1.094774e-7	0.000007567077888	2.306748	50	0.02813731	39	0.011997854030769231	1.724438	42	202	0.01855124	
GO Cellular Component	ribosome	27	1.916753e-7	0.0000122672192	2.262884	50	0.02813731	40	0.0149060088	1.651717	47	236	0.02075972	
GO Cellular Component	ribosomal subunit	29	3.494563e-7	0.000020822775393103446	2.511417	39	0.0219471	43	0.02652196286511628	1.703577	38	185	0.01678445	
GO Cellular Component	ribonucleoprotein granule	31	4.007172e-7	0.00002233675230967742	2.130327	54	0.03038829	30	0.00012205837439999999	1.999001	47	195	0.02075972	
GO Cellular Component	cytoplasmic ribonucleoprotein granule	35	8.513072e-7	0.00004203025261714286	2.128527	51	0.02870006	31	0.0003066605790967742	1.983283	44	184	0.01943463	
GO Cellular Component	spliceosomal complex	40	0.00001820746	0.000786562272	2.029021	43	0.02419809	36	0.0085882032	1.783597	40	186	0.01766784	
GO Cellular Component	cytoplasmic stress granule	58	0.0002673987	0.007966637131034482	2.825228	16	0.009003939	50	0.04192843392	2.507406	13	43	0.005742049	
GO Cellular Component	U1 snRNP	73	0.0008518882	0.02016524396712329	4.15767	8	0.00450197	46	0.03656546420869565	3.492096	8	19	0.003533569	
GO Cellular Component	nucleotide-excision repair complex	74	0.0009183701	0.021445182875675674	4.108588	8	0.00450197	48	0.0351979956	3.870406	7	15	0.003091873	
GO Molecular Function	RNA helicase activity	7	0.0000606534	0.03658266497142857	2.628626	22	0.01238042	41	0.010402225385365853	2.439332	20	68	0.008833922	
GO Molecular Function	ATP-dependent helicase activity	8	0.00006604499	0.0348552434725	2.30016	28	0.01575689	45	0.014883094168888888	2.137559	25	97	0.0110424	
GO Molecular Function	ATP-dependent RNA helicase activity	13	0.0001437162	0.04667459972307692	2.534765	21	0.01181767	46	0.02320789344347826	2.351953	19	67	0.008392226	
GO Molecular Function	RNA-dependent ATPase activity	18	0.0001874459	0.043966477211111105	2.484481	21	0.01181767	48	0.02741962947083333	2.317365	19	68	0.008392226	
Human Phenotype	Cardiomegaly	2	0.000006568629	0.0219162306585	3.536276	18	0.01012943	37	0.013651015615945944	3.055584	14	38	0.006183746	
Mouse Phenotype	decreased fibroblast proliferation	5	4.392153e-9	0.0000083986749666	2.656273	47	0.02644907	11	0.007114092383181817	2.169129	34	130	0.01501767	
Mouse Phenotype	increased fibroblast apoptosis	26	0.00004627052	0.01701509391230769	3.040659	18	0.01012943	15	0.015292647402	2.937362	17	48	0.007508834