# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	mRNA catabolic process	13	1.774722e-26	1.796428215230769e-23	2.113113	250	0.0255024	176	8.97419126875e-7	1.492506	123	213	0.01693049	
GO Biological Process	nuclear-transcribed mRNA catabolic process	14	1.947512e-26	1.8305221719999996e-23	2.177912	233	0.02376823	184	0.0000016259353371195652	1.501147	115	198	0.01582932	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	19	1.340111e-24	9.281326657368422e-22	2.467061	167	0.0170356	518	0.01710215531833977	1.395218	61	113	0.008396421	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	22	8.724115e-23	5.218210422045455e-20	2.606992	139	0.01417933	244	0.00009692132017213115	1.555131	71	118	0.009772884	
GO Biological Process	regulation of intrinsic apoptotic signaling pathway	23	1.122579e-22	6.422616113478261e-20	2.10458	214	0.02183005	313	0.0006573290465495208	1.434027	86	155	0.01183758	
GO Biological Process	IRE1-mediated unfolded protein response	30	1.441384e-21	6.322390685333334e-19	3.261073	92	0.009384882	440	0.007779295750454545	1.604224	36	58	0.004955265	
GO Biological Process	regulation of DNA-templated transcription in response to stress	31	1.458812e-21	6.192421647741935e-19	2.259342	173	0.01764766	444	0.008767871337387387	1.411747	65	119	0.008947006	
GO Biological Process	regulation of hematopoietic progenitor cell differentiation	35	2.451167e-20	9.21568758657143e-18	2.48699	134	0.01366928	518	0.01710215531833977	1.395218	61	113	0.008396421	
GO Biological Process	multi-organism metabolic process	38	8.969215e-20	3.1059447417105264e-17	2.187475	169	0.01723962	272	0.0002027007522132353	1.476905	84	147	0.01156228	
GO Biological Process	ribonucleoprotein complex export from nucleus	43	2.761983e-19	8.452310301627907e-17	2.327945	144	0.01468938	218	0.00002646248944174312	1.571427	76	125	0.01046111	
GO Biological Process	viral gene expression	45	8.663936e-19	2.533527418311111e-16	2.344079	138	0.01407732	335	0.0011184631496119403	1.465276	72	127	0.00991053	
GO Biological Process	viral transcription	46	1.006723e-18	2.879884338478261e-16	2.401358	131	0.01336326	284	0.0003275218108556338	1.532452	67	113	0.009222299	
GO Biological Process	mRNA export from nucleus	53	5.247892e-18	1.3029624684528301e-15	2.396623	126	0.01285321	275	0.00023203293410545454	1.560503	64	106	0.00880936	
GO Biological Process	ribonucleoprotein complex localization	54	5.343659e-18	1.3021705329814816e-15	2.245625	144	0.01468938	235	0.0000597205256212766	1.54668	76	127	0.01046111	
GO Biological Process	cellular response to topologically incorrect protein	57	1.96584e-17	4.5383313263157895e-15	2.077021	166	0.01693359	247	0.00011500108267611334	1.506124	81	139	0.01114935	
GO Biological Process	regulation of mitochondrial membrane permeability	58	3.393097e-17	7.698235072931035e-15	2.336814	126	0.01285321	206	0.00001486832854854369	1.770263	50	73	0.006882312	
GO Biological Process	endoplasmic reticulum unfolded protein response	59	3.447639e-17	7.68940366118644e-15	2.208108	142	0.01448536	298	0.0004722199881208054	1.51901	67	114	0.009222299	
GO Biological Process	cellular response to unfolded protein	70	6.547753e-16	1.2308840246714286e-13	2.077348	150	0.01530144	282	0.00029828088589007093	1.516574	71	121	0.009772884	
GO Biological Process	regulation of membrane permeability	82	5.93809e-15	9.529186135365855e-13	2.136613	131	0.01336326	231	0.00005521757933160174	1.691147	53	81	0.007295251	
GO Biological Process	protein targeting to ER	85	1.098339e-14	1.700357988352941e-12	2.312567	108	0.01101704	322	0.0007869617350621117	1.535396	60	101	0.008258775	
GO Cellular Component	nuclear chromosome, telomeric region	40	2.725118e-15	1.177250976e-13	2.131928	135	0.01377129	57	0.0000012198882694736842	1.605575	82	132	0.01128699	
GO Cellular Component	methyltransferase complex	51	1.441329e-12	4.883561788235293e-11	2.062535	117	0.01193512	142	0.0283533403943662	1.391699	49	91	0.006744666	
GO Cellular Component	peptidase complex	52	2.280782e-12	7.57921403076923e-11	2.151377	104	0.010609	131	0.023775340946564888	1.409773	48	88	0.00660702	
GO Cellular Component	spliceosomal snRNP complex	57	5.114489e-11	1.550497717894737e-9	2.474152	68	0.006936652	126	0.02095972114285714	1.500726	36	62	0.004955265	
GO Cellular Component	PcG protein complex	59	6.561664e-11	1.9217890494915254e-9	2.172036	88	0.008976844	95	0.004372367494736843	1.685598	30	46	0.004129387	
GO Cellular Component	small nuclear ribonucleoprotein complex	65	5.362964e-10	1.4257233526153844e-8	2.242506	74	0.00754871	113	0.013698666477876107	1.498309	40	69	0.00550585	
GO Cellular Component	host cell	72	4.110612e-9	9.8654688e-8	2.034371	83	0.008466796	152	0.03363099536842105	1.444326	38	68	0.005230557	
GO Cellular Component	U2 snRNP	74	5.171695e-9	1.2076606702702704e-7	3.695179	29	0.002958278	139	0.026194304460431656	1.90443	14	19	0.001927047	
GO Cellular Component	mitochondrial outer membrane translocase complex	92	2.612692e-7	0.000004907317147826087	4.070368	20	0.002040192	165	0.047575180800000005	2.114659	9	11	0.001238816	
GO Cellular Component	U2-type prespliceosome	116	0.000009487341	0.0001413286659310345	2.991981	22	0.002244211	161	0.03784486360248447	1.938438	12	16	0.001651755	
GO Cellular Component	nuclear telomere cap complex	118	0.00001115597	0.00016336878101694914	2.801472	24	0.00244823	116	0.014053365186206897	2.186955	11	13	0.001514109	
GO Cellular Component	mRNA cleavage factor complex	133	0.00002699569	0.00035074099488721807	2.480996	27	0.002754259	164	0.04768410731707318	1.809209	14	20	0.001927047	
GO Cellular Component	box C/D snoRNP complex	142	0.00003478959	0.00042335501070422536	5.177213	10	0.001020096	158	0.03664318055696202	2.584584	6	6	0.0008258775	
GO Cellular Component	transcription factor TFIIIC complex	303	0.007166262	0.04086897932673267	3.206214	7	0.0007140671	158	0.03664318055696202	2.584584	6	6	0.0008258775	
GO Molecular Function	telomeric DNA binding	15	3.240656e-12	9.121366421333334e-10	2.906642	58	0.005916556	67	0.0005192124858507463	1.976446	26	34	0.003578802	
GO Molecular Function	peptide disulfide oxidoreductase activity	52	8.154065e-7	0.0000662047354423077	3.501411	22	0.002244211	106	0.03757568847547169	2.186955	11	13	0.001514109	
Human Phenotype	Dysphonia	104	0.000003735234	0.00023966554309615384	2.310466	38	0.003876364	114	0.03801223524473685	1.910344	17	23	0.002339986	
Human Phenotype	Ependymoma	335	0.001277671	0.025450443531343285	3.052598	11	0.001122105	105	0.03184054361714286	2.584584	8	8	0.00110117	
Mouse Phenotype	increased embryonic neuroepithelium apoptosis	24	4.044242e-15	1.61112490675e-12	3.270161	62	0.006324595	223	0.03228708111793722	1.8609	18	25	0.002477632	
Mouse Phenotype	increased neural tube apoptosis	32	7.764327e-14	2.3198353264687502e-11	2.629835	79	0.008058758	120	0.00282026792625	1.803198	30	43	0.004129387	
Mouse Phenotype	abnormal vertebral transverse process morphology	219	0.00008468896	0.003697311171506849	2.201706	30	0.003060288	201	0.025415269008955223	2.349621	10	11	0.001376462	
Mouse Phenotype	decreased brown fat cell size	358	0.00103035	0.027517252374301675	2.054664	24	0.00244823	257	0.04699082690661478	2.326125	9	10	0.001238816