# GREAT version 4.0.4 Species assembly: hg38 Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included # Ontology Term Name Binom Rank Binom Raw P-Value Binom FDR Q-Val Binom Fold Enrichment Binom Observed Region Hits Binom Region Set Coverage Hyper Rank Hyper FDR Q-Val Hyper Fold Enrichment Hyper Observed Gene Hits Hyper Total Genes Hyper Gene Set Coverage GO Biological Process glomerular epithelium development 3 0.000002371035 0.010400149855 3.998136 17 0.014419 106 0.03295938454245283 4.298764 8 21 0.004807692 Mouse Phenotype Single KO abnormal otolith morphology 16 2.885584e-8 0.00001651455793 4.443552 21 0.0178117 310 0.032493112341935484 3.276074 9 31 0.005408654 Mouse Phenotype Single KO abnormal otolithic membrane morphology 17 5.841713e-8 0.00003146621525941176 4.257696 21 0.0178117 373 0.04394957386595174 3.077524 9 33 0.005408654 Mouse Phenotype Single KO abnormal stria vascularis morphology 26 0.000002262996 0.0007970097835384615 3.163783 23 0.01950806 249 0.024464157465863452 3.027483 11 41 0.006610577 Mouse Phenotype Single KO abnormal semicircular canal ampulla morphology 32 0.000008256728 0.00236271432175 3.004059 22 0.01865988 203 0.013708376334482757 3.52633 10 32 0.006009615 Mouse Phenotype Single KO head bobbing 45 0.00004224439 0.008596263982888888 2.55903 24 0.02035623 231 0.020954082022077925 3.10317 11 40 0.006610577 Mouse Phenotype Single KO abnormal vestibular saccule morphology 47 0.00005112399 0.00996047609425532 2.527198 24 0.02035623 229 0.02026831173187773 2.943719 12 46 0.007211538 Mouse Phenotype Single KO abnormal inner ear vestibule morphology 50 0.00009980579 0.0182784323806 2.168137 30 0.02544529 148 0.005038108391486487 2.780179 17 69 0.01021635 Mouse Phenotype Single KO abnormal kidney blood vessel morphology 52 0.000118097 0.02079642748076923 2.502408 22 0.01865988 127 0.0031976323312598426 2.90655 17 66 0.01021635 Mouse Phenotype Single KO abnormal otolith organ morphology 53 0.0001198603 0.020708693718867927 2.338079 25 0.02120441 227 0.018951879847136564 2.821064 13 52 0.0078125 Mouse Phenotype Single KO abnormal adipose tissue physiology 65 0.0002902084 0.04088366644307693 2.163222 26 0.02205259 250 0.024743642492 2.233342 19 96 0.01141827 Mouse Phenotype unidirectional circling 7 4.542117e-9 0.000006203882948142858 6.774893 16 0.01357082 502 0.04818067873505976 4.701773 5 12 0.003004808 Mouse Phenotype abnormal otolith morphology 12 1.655904e-8 0.00001319341512 4.39407 22 0.01865988 290 0.013243396071724138 3.419471 10 33 0.006009615 Mouse Phenotype abnormal otolithic membrane morphology 13 3.564182e-8 0.00002621318777076923 4.202836 22 0.01865988 364 0.02266548258543956 3.134515 10 36 0.006009615 Mouse Phenotype abnormal stria vascularis morphology 24 0.000004018659 0.001600933279125 3.053045 23 0.01950806 380 0.02584454038421053 2.88667 11 43 0.006610577 Mouse Phenotype abnormal cochlear inner hair cell number 27 0.000006846788 0.0024245237062222222 3.041177 22 0.01865988 311 0.016118250450482315 3.318898 10 34 0.006009615 Mouse Phenotype abnormal vestibular saccule morphology 32 0.000010888 0.0032531302499999998 2.454749 30 0.02544529 123 0.0011041835663414634 3.282692 16 55 0.009615385 Mouse Phenotype abnormal semicircular canal ampulla morphology 41 0.00006256155 0.014589048281707316 2.493699 24 0.02035623 293 0.013581429868259385 3.182739 11 39 0.006610577 Mouse Phenotype abnormal utricle morphology 42 0.00006435564 0.014650101762857142 2.435245 25 0.02120441 389 0.027899981136246785 2.708221 12 50 0.007211538 Mouse Phenotype abnormal kidney blood vessel morphology 44 0.0000823819 0.017901212406818183 2.26479 28 0.02374894 180 0.004386313249166667 2.468431 21 96 0.01262019 Mouse Phenotype abnormal otolith organ morphology 47 0.000104121 0.02118086980851064 2.131342 31 0.02629347 140 0.0019692689260714285 2.99738 17 64 0.01021635 Mouse Phenotype abnormal cochlear hair cell stereociliary bundle morphology 49 0.000112945 0.022038105 2.152463 30 0.02544529 480 0.04288114475625 2.13147 17 90 0.01021635 Mouse Phenotype head bobbing 50 0.0001229879 0.023517746238 2.334086 25 0.02120441 350 0.021001383916285716 2.821064 12 48 0.007211538