# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	mitochondrial transport	71	1.0686e-69	1.9805221690140843e-67	2.00869	779	0.03087839	240	0.000006822217755	1.244553	189	239	0.01584109	
GO Biological Process	cellular response to insulin stimulus	73	7.553698e-69	1.3616316709863014e-66	2.081929	705	0.02794514	445	0.0009240193615505619	1.244152	117	148	0.009806387	
GO Biological Process	regulation of intrinsic apoptotic signaling pathway	96	1.768599e-58	2.4242702334375e-56	2.140011	560	0.02219756	957	0.04193892927272727	1.167658	115	155	0.009638756	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	99	2.796291e-57	3.716807400909091e-55	2.422434	422	0.01672745	825	0.023819081974545454	1.211686	87	113	0.007291929	
GO Biological Process	regulation of mRNA stability	103	3.066169e-56	3.917254162233009e-54	2.065357	585	0.02318852	984	0.046627151268292685	1.167321	112	151	0.00938731	
GO Biological Process	nuclear-transcribed mRNA catabolic process	124	5.896411e-52	6.257328415241936e-50	2.033989	560	0.02219756	350	0.00018722049963714284	1.232015	155	198	0.01299137	
GO Biological Process	regulation of DNA-templated transcription in response to stress	126	9.201517e-52	9.609743031984126e-50	2.248101	443	0.01755985	750	0.015231056494266666	1.216719	92	119	0.007711005	
GO Biological Process	cellular response to epidermal growth factor stimulus	156	2.110327e-46	1.780114935448718e-44	2.638112	290	0.01149516	804	0.021854758531094524	1.36672	33	38	0.002765904	
GO Biological Process	cotranslational protein targeting to membrane	164	9.40118e-45	7.543300464634145e-43	2.568508	293	0.01161408	381	0.0003199200883254593	1.316853	82	98	0.006872852	
GO Biological Process	protein targeting to ER	179	1.610936e-41	1.1842629510614526e-39	2.454532	295	0.01169336	338	0.00015285856467159764	1.324485	85	101	0.007124298	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	181	4.260932e-41	3.09776818718232e-39	2.339409	321	0.01272396	326	0.00010143833121165644	1.307054	98	118	0.008213897	
GO Biological Process	liver regeneration	192	3.259421e-39	2.2338917155729165e-37	2.889118	209	0.008284446	577	0.004193369635701907	1.438902	32	35	0.002682089	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	213	2.139941e-37	1.3220414844600936e-35	2.461704	263	0.01042492	466	0.0013835028093991417	1.300095	76	92	0.006369961	
GO Biological Process	multi-organism metabolic process	221	7.375867e-37	4.3918114865610853e-35	2.016866	401	0.01589504	454	0.0011363153010352422	1.24191	116	147	0.009722571	
GO Biological Process	regulation of mitochondrial membrane permeability	224	1.417838e-36	8.329165286607143e-35	2.24125	311	0.01232757	556	0.0033487714284172665	1.315093	61	73	0.005112732	
GO Biological Process	regulation of membrane permeability	234	1.259256e-35	7.081431497435898e-34	2.1358	337	0.01335817	539	0.0030838934359925787	1.301785	67	81	0.005615623	
GO Biological Process	establishment of protein localization to endoplasmic reticulum	249	6.04034e-34	3.192162010441767e-32	2.195177	301	0.01193119	388	0.0003758695383762887	1.304005	87	105	0.007291929	
GO Biological Process	protein localization to endoplasmic reticulum	263	7.768347e-33	3.886831869695818e-31	2.055257	339	0.01343745	552	0.003275611226630435	1.243809	98	124	0.008213897	
GO Biological Process	response to cadmium ion	264	8.240574e-33	4.107489138863636e-31	2.547127	215	0.008522277	955	0.04161099020732984	1.27532	47	58	0.003939318	
GO Biological Process	viral gene expression	287	8.26009e-31	3.787265655400697e-29	2.065921	313	0.01240685	440	0.0008774274656590909	1.263996	102	127	0.008549158	
GO Cellular Component	cytoplasmic stress granule	122	9.753876e-19	1.3815326006557377e-17	2.126837	171	0.006778183	95	0.004630674391578947	1.390799	38	43	0.00318498	
GO Molecular Function	cadherin binding	6	1.296241e-126	9.121215836666667e-124	2.02789	1379	0.05466149	9	1.0046816624444445e-11	1.309774	253	304	0.02120526	
GO Molecular Function	rRNA binding	46	3.815032e-25	3.501535892173913e-23	2.780038	139	0.005509751	96	0.00919650553125	1.337729	51	60	0.004274579	
Human Phenotype	Increased serum ferritin	9	7.185336e-30	5.327527458666667e-27	4.512301	88	0.003488188	93	0.008209698621505376	1.573799	20	20	0.001676305	
Mouse Phenotype Single KO	decreased circulating free fatty acid level	54	2.044845e-43	3.467526975e-41	2.142768	411	0.01629142	349	0.006738053820343839	1.269193	75	93	0.006286145	
Mouse Phenotype Single KO	abnormal cell adhesion	78	1.539267e-35	1.8070599896153846e-33	2.114714	344	0.01363564	420	0.01868609033452381	1.307054	49	59	0.004106948	
Mouse Phenotype Single KO	pale liver	124	3.17726e-29	2.3463040177419354e-27	2.046275	303	0.01201046	378	0.010659855076455027	1.278712	65	80	0.005447993	
Mouse Phenotype Single KO	abnormal branching of the mammary ductal tree	158	4.37846e-25	2.5375669759493672e-23	2.010862	269	0.01066276	199	0.0003777846891457287	1.490968	36	38	0.00301735	
Mouse Phenotype Single KO	increased liver adenoma incidence	339	6.252514e-16	1.688916539764012e-14	2.627034	93	0.00368638	462	0.02833425536363636	1.495109	19	20	0.00159249	
Mouse Phenotype Single KO	abnormal urine chloride ion level	864	4.365351e-8	4.626564711458333e-7	2.197439	60	0.00237831	399	0.016143467406766917	1.573799	16	16	0.001341044	
Mouse Phenotype	extramedullary hematopoiesis	24	5.092016e-74	2.0285318739999997e-71	2.044905	792	0.03139369	711	0.035695489227848105	1.160115	129	175	0.01081217	
Mouse Phenotype	decreased circulating free fatty acid level	71	2.869978e-52	3.864768965915493e-50	2.077734	535	0.0212066	226	0.00008064191605752212	1.309295	99	119	0.008297712	
Mouse Phenotype	abnormal cell adhesion	110	9.758188e-41	8.481639588e-39	2.04295	431	0.01708419	300	0.0005859156085000001	1.346013	65	76	0.005447993	
Mouse Phenotype	pancytopenia	398	6.905124e-18	1.6587912202010052e-16	2.251334	143	0.005668305	463	0.006021455849676026	1.465261	27	29	0.002263012	
Mouse Phenotype	decreased liver cholesterol level	409	2.033766e-17	4.754238808312958e-16	2.161438	152	0.006025052	516	0.01025437261395349	1.426256	29	32	0.002430643