# GREAT version 4.0.4 Species assembly: hg38 Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included # Ontology Term Name Binom Rank Binom Raw P-Value Binom FDR Q-Val Binom Fold Enrichment Binom Observed Region Hits Binom Region Set Coverage Hyper Rank Hyper FDR Q-Val Hyper Fold Enrichment Hyper Observed Gene Hits Hyper Total Genes Hyper Gene Set Coverage GO Biological Process mesoderm formation 16 0.00003147476 0.025886022927500002 2.31706 30 0.02367798 17 0.000001123729060235294 3.807795 25 67 0.01358696 GO Biological Process mesoderm morphogenesis 20 0.00007676081 0.05050477493950001 2.202526 30 0.02367798 20 0.0000019505177770999997 3.697424 25 69 0.01358696 Mouse Phenotype Single KO unidirectional circling 9 1.375484e-13 1.3994785542222222e-10 8.845391 21 0.01657459 240 0.03081157661625 5.669384 5 9 0.002717391 Mouse Phenotype Single KO bidirectional circling 35 1.958065e-8 0.0000051228574871428565 4.024648 24 0.01894238 300 0.04468695360666666 3.40163 8 24 0.004347826 Mouse Phenotype Single KO circling 41 3.750098e-7 0.00008375523752682927 2.293363 46 0.03630624 73 0.0016235097579452055 2.551223 24 96 0.01304348 Mouse Phenotype Single KO abnormal vestibular labyrinth morphology 54 0.00001453358 0.002464518371481481 2.210072 36 0.02841358 171 0.01679115877017544 2.416948 18 76 0.009782609 Mouse Phenotype Single KO abnormal otolith organ morphology 58 0.00002413019 0.003809657755689655 2.436769 28 0.02209945 280 0.03967845832857143 2.551223 13 52 0.007065217 Mouse Phenotype Single KO decreased paired-pulse facilitation 61 0.00003448067 0.005176057298196721 3.55752 15 0.01183899 155 0.013884717745806453 4.296796 8 19 0.004347826 Mouse Phenotype Single KO abnormal pinna reflex 66 0.00007862509 0.010908635592878788 2.13625 32 0.02525651 200 0.021680355860500003 2.409488 17 72 0.00923913 Mouse Phenotype Single KO heart valve hyperplasia 76 0.000242866 0.029262157394736844 7.108626 6 0.004735596 119 0.0070744781242016806 10.20489 4 4 0.002173913 Mouse Phenotype Single KO conjunctivitis 83 0.0004100585 0.04523982752409638 3.102113 13 0.01026046 267 0.03658701642322098 3.549527 8 23 0.004347826 Mouse Phenotype unidirectional circling 4 5.416166e-14 1.29459907815e-10 8.668468 22 0.01736385 301 0.015303403304651164 5.102446 6 12 0.00326087 Mouse Phenotype bidirectional circling 29 1.958065e-8 0.000006455537746551724 4.024648 24 0.01894238 416 0.03364796294711538 3.40163 8 24 0.004347826 Mouse Phenotype circling 41 0.000002584162 0.0006026139727317074 2.056034 50 0.0394633 115 0.0014370648579130434 2.323065 28 123 0.01521739 Mouse Phenotype abnormal utricle morphology 47 0.00001184269 0.0024091055125531912 2.538037 28 0.02209945 518 0.0495253709015444 2.449174 12 50 0.006521739 Mouse Phenotype decreased paired-pulse facilitation 50 0.00001340724 0.0025637324328 3.345305 18 0.01420679 303 0.016185870542574258 3.2919 10 31 0.005434783 Mouse Phenotype abnormal semicircular canal ampulla morphology 54 0.00002793244 0.004945593682222222 2.513873 26 0.02052092 365 0.02555325772931507 2.878303 11 39 0.005978261 Mouse Phenotype abnormal otolith organ morphology 55 0.0000337829 0.0058726964890909086 2.175242 34 0.02683504 127 0.002119011205511811 2.870126 18 64 0.009782609 Mouse Phenotype abnormal vestibular saccule morphology 57 0.00004057301 0.006805588572105264 2.284253 30 0.02367798 322 0.0194938872689441 2.597609 14 55 0.007608696 Mouse Phenotype abnormal ectomesenchyme morphology 63 0.00008527478 0.01294146304095238 8.643033 6 0.004735596 104 0.0008266033338173076 10.20489 5 5 0.002717391 Mouse Phenotype abnormal mesenchyme morphology 66 0.0001163952 0.016861431927272727 4.076983 11 0.008681926 93 0.00032982643383870966 5.370995 10 19 0.005434783 Mouse Phenotype abnormal pinna reflex 71 0.0001772883 0.02387399206056338 2.040154 32 0.02525651 324 0.019587178061111113 2.344367 17 74 0.00923913 Mouse Phenotype increased IgG2b level 76 0.0002439481 0.030689312948684207 2.84617 16 0.01262826 475 0.04230100403368421 2.412065 13 55 0.007065217