# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	response to ischemia	64	3.221702e-10	6.6241213465625e-8	3.93856	31	0.01546135	133	0.02361764457819549	2.900164	13	36	0.005560308	
GO Biological Process	regulation of extrinsic apoptotic signaling pathway in absence of ligand	68	1.999266e-7	0.000038688737197058816	2.954318	31	0.01546135	70	0.003616239828857143	2.968061	17	46	0.007271172	
GO Biological Process	positive regulation of JUN kinase activity	90	0.000009332031	0.0013644466214333332	2.234802	37	0.01845387	106	0.012405143235471698	2.433704	20	66	0.00855432	
GO Biological Process	embryonic hindlimb morphogenesis	121	0.00005180575	0.005633982349173554	2.295113	29	0.01446384	31	0.000018455344685806453	4.43102	16	29	0.006843456	
GO Biological Process	mammary gland epithelium development	132	0.00008156752	0.008131416633939393	2.010474	37	0.01845387	177	0.04734356171694915	2.379622	16	54	0.006843456	
GO Biological Process	ventricular septum morphogenesis	140	0.00009959903	0.009361597398357142	2.034971	35	0.01745636	52	0.0005012549055192308	3.569433	16	36	0.006843456	
GO Biological Process	leukocyte apoptotic process	171	0.0001921164	0.014783974898245613	3.189672	14	0.006982544	80	0.005755001471625	3.84102	11	23	0.004704876	
GO Biological Process	cell surface receptor signaling pathway involved in heart development	190	0.0003175331	0.021991674015263155	2.448286	20	0.009975062	101	0.010935056039207918	3.824392	10	21	0.00427716	
GO Biological Process	lymphocyte apoptotic process	239	0.0007837586	0.043152633545606695	3.243407	11	0.005486284	108	0.014565758021296296	4.015612	9	18	0.003849444	
GO Molecular Function	signal transducer, downstream of receptor, with serine/threonine kinase activity	13	1.81246e-7	0.000058863124	2.545445	40	0.01995012	22	0.04668420846363636	2.294635	20	70	0.00855432	
Human Phenotype	Abnormal ventricular septum morphology	2	1.969529e-11	6.571333508499999e-8	2.139557	94	0.04688279	10	0.007982456136	1.940127	43	178	0.01839179	
Human Phenotype	Renal hypoplasia	25	2.138429e-7	0.00005707894686800001	2.376199	45	0.02244389	17	0.014336489091176472	2.844392	17	48	0.007271172	
Human Phenotype	Abnormality of the choanae	26	2.979938e-7	0.0000764812549	2.787316	33	0.01645885	77	0.04142763925064935	2.614817	14	43	0.005988024	
Human Phenotype	Bifid uvula	163	0.0002507335	0.010264691076687118	2.152722	27	0.01346633	51	0.022501447590196077	2.983026	13	35	0.005560308	
Human Phenotype	Abnormality of the uvula	186	0.0004355811	0.015627057420967743	2.075306	27	0.01346633	59	0.026998177598305084	2.900164	13	36	0.005560308	
Mouse Phenotype Single KO	abnormal negative T cell selection	70	0.00002106581	0.0027557088881428574	4.212756	13	0.006483791	120	0.030338163531666667	4.324505	7	13	0.002994012	
Mouse Phenotype Single KO	common atrioventricular valve	148	0.0001868624	0.011561479708108108	2.80997	17	0.008478803	62	0.006068141559838709	4.942291	8	13	0.003421728	
Mouse Phenotype Single KO	ostium primum atrial septal defect	224	0.0006224173	0.025444085786160715	2.37802	19	0.009476309	128	0.034958671746093746	3.779399	8	17	0.003421728	
Mouse Phenotype Single KO	ectopic ovary	253	0.0009836595	0.035602253128458494	3.380221	10	0.004987531	129	0.03573103280852714	5.736588	5	7	0.00213858	
Mouse Phenotype Single KO	abnormal T cell clonal deletion	267	0.001177646	0.040388406074906374	4.468702	7	0.003491272	94	0.015622777182978723	6.692686	5	6	0.00213858	
Mouse Phenotype	abnormal lung weight	84	0.000006137648	0.0006985958634285714	2.127132	43	0.02144638	163	0.022450313144171778	2.277511	19	67	0.008126604	
Mouse Phenotype	impaired lung alveolus development	106	0.00001678865	0.001514304553301887	2.229602	35	0.01745636	191	0.04005621496649214	2.498603	14	45	0.005988024	
Mouse Phenotype	common atrioventricular valve	143	0.00004738954	0.003168471272307692	2.750838	21	0.01047382	61	0.0023280580460655737	4.461791	10	18	0.00427716	
Mouse Phenotype	iris synechia	220	0.0002159576	0.00938532097090909	2.399573	22	0.01097257	183	0.036645975504918035	3.088932	10	26	0.00427716	
Mouse Phenotype	increased susceptibility to otitis media	267	0.0003778862	0.01353172268988764	2.354631	21	0.01047382	156	0.01878929558653846	3.155123	11	28	0.004704876	
Mouse Phenotype	decreased cranium height	272	0.0004022161	0.014138191662132352	2.289994	22	0.01097257	141	0.016186372929787234	2.900164	13	36	0.005560308	
Mouse Phenotype	ostium primum atrial septal defect	326	0.0008451485	0.02478670186656442	2.16147	22	0.01097257	131	0.0156915132	3.491836	10	23	0.00427716	
Mouse Phenotype	absent hair follicle melanin granules	434	0.001999533	0.044049619845622126	2.598388	13	0.006483791	135	0.015739891859999997	5.354149	6	9	0.002566296