# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	liver regeneration	17	9.063511e-29	7.015690661705883e-26	4.087477	94	0.0117207	337	0.03344484411454006	1.828632	21	35	0.003408538	
GO Biological Process	regulation of intrinsic apoptotic signaling pathway	35	9.962752e-24	3.7457101019428565e-21	2.271947	189	0.02356608	264	0.007200001679166667	1.435378	73	155	0.01184873	
GO Biological Process	endoplasmic reticulum unfolded protein response	50	1.241212e-21	3.2666217416e-19	2.565963	135	0.01683292	236	0.0026600985410169488	1.550594	58	114	0.009414056	
GO Biological Process	protein targeting to ER	59	1.624451e-20	3.623076391355932e-18	2.826695	108	0.01346633	162	0.00018114695645679013	1.689825	56	101	0.009089434	
GO Biological Process	rRNA metabolic process	60	1.717961e-20	3.767774799833333e-18	2.006007	215	0.02680798	88	6.47075880909091e-7	1.529743	130	259	0.02110047	
GO Biological Process	rRNA processing	62	1.944473e-20	4.1269871301612904e-18	2.02269	210	0.02618454	93	0.0000014168479243010752	1.52386	126	252	0.02045123	
GO Biological Process	cellular response to topologically incorrect protein	70	8.911631e-19	1.675259318985714e-16	2.263493	148	0.01845387	377	0.047667552530503976	1.381341	63	139	0.01022561	
GO Biological Process	nuclear-transcribed mRNA catabolic process	71	9.918835e-19	1.838337320633803e-16	2.067986	181	0.02256858	190	0.000813073832631579	1.446897	94	198	0.01525726	
GO Biological Process	cotranslational protein targeting to membrane	76	2.04346e-18	3.538143439473684e-16	2.75754	100	0.01246883	159	0.00013596333985534592	1.710455	55	98	0.008927122	
GO Biological Process	cellular response to unfolded protein	79	2.51862e-18	4.1952557696202535e-16	2.31912	137	0.01708229	245	0.004977982025142856	1.511266	60	121	0.009738679	
GO Biological Process	establishment of protein localization to endoplasmic reticulum	90	1.977718e-17	2.891643462444445e-15	2.523505	110	0.01371571	171	0.00034159755912865496	1.654476	57	105	0.009251745	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	105	1.297006e-16	1.625457328952381e-14	2.708797	92	0.01147132	178	0.00046423998342134834	1.689497	51	92	0.008277877	
GO Biological Process	mitochondrial translational termination	106	1.523369e-16	1.8911332708490565e-14	2.832996	85	0.0105985	101	0.00000260799133009901	1.891688	54	87	0.008764811	
GO Biological Process	DNA-dependent DNA replication	109	5.249051e-16	6.336904780642202e-14	2.123978	143	0.01783042	241	0.003587707435145228	1.537111	58	115	0.009414056	
GO Biological Process	mitochondrial translation	112	5.43373e-16	6.384147595535715e-14	2.523537	100	0.01246883	103	0.0000032869010126213593	1.794452	63	107	0.01022561	
GO Biological Process	viral gene expression	117	1.009095e-15	1.134930008974359e-13	2.346153	113	0.01408978	122	0.000018702519973770494	1.679845	70	127	0.01136179	
GO Biological Process	translational elongation	119	1.391348e-15	1.53855028e-13	2.422422	105	0.01309227	129	0.000027031952255813952	1.714342	63	112	0.01022561	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	120	2.067533e-15	2.2672222289166668e-13	2.407126	105	0.01309227	291	0.014883077709621995	1.472203	57	118	0.009251745	
GO Biological Process	regulation of mitophagy	125	3.114812e-15	3.27902488864e-13	3.024315	70	0.00872818	363	0.04349064000275482	1.685973	26	47	0.004220094	
GO Biological Process	mitochondrial translational elongation	128	4.093751e-15	4.2085679225781247e-13	2.744436	81	0.01009975	113	0.000008473650711504425	1.864487	52	85	0.008440188	
GO Cellular Component	ribosomal subunit	40	1.034864e-18	4.4706124800000007e-17	2.211561	155	0.01932668	33	9.566585018181818e-8	1.647416	100	185	0.01623113	
GO Cellular Component	catalytic step 2 spliceosome	41	1.439025e-17	6.064963902439024e-16	2.510834	112	0.01396509	53	0.00040644288	1.650848	52	96	0.008440188	
GO Cellular Component	mitochondrial ribosome	42	3.783315e-17	1.5565638857142858e-15	3.071771	78	0.009725686	40	0.0000031434739199999995	1.864487	52	85	0.008440188	
GO Cellular Component	PcG protein complex	47	1.28416e-14	4.721337191489362e-13	2.594582	86	0.01072319	82	0.016369078478048783	1.722624	26	46	0.004220094	
GO Cellular Component	methyltransferase complex	52	4.742533e-13	1.575980196923077e-11	2.219408	103	0.01284289	50	0.0003720612096	1.674571	50	91	0.008115566	
GO Cellular Component	large ribosomal subunit	55	1.892392e-12	5.945551592727273e-11	2.247288	95	0.01184539	55	0.0009431248058181819	1.563613	59	115	0.009576367	
GO Cellular Component	mitochondrial large ribosomal subunit	61	3.712147e-11	1.0515721337704918e-9	3.114106	47	0.005860349	57	0.0035679107368421057	1.792776	30	51	0.004869339	
GO Cellular Component	U5 snRNP	64	7.020836e-11	1.89562572e-9	4.100056	32	0.003990025	106	0.04791041388679246	1.939458	14	22	0.002272358	
GO Cellular Component	spliceosomal snRNP complex	65	1.048137e-10	2.7864319015384613e-9	2.623942	59	0.007356608	78	0.015577071507692306	1.622173	33	62	0.005356273	
GO Cellular Component	histone methyltransferase complex	67	2.165003e-10	5.5837689313432834e-9	2.14959	85	0.0105985	77	0.015120938057142857	1.590115	36	69	0.005843207	
GO Cellular Component	small nuclear ribonucleoprotein complex	85	1.239587e-8	2.520007454117647e-7	2.259521	61	0.007605985	98	0.0269165093877551	1.545945	35	69	0.005680896	
GO Cellular Component	small ribosomal subunit	86	1.507303e-8	3.0286274232558135e-7	2.213716	63	0.007855362	46	0.00009097198747826087	1.820166	43	72	0.006979386	
GO Cellular Component	methylosome	114	0.000001976345	0.000029957229473684207	4.569494	15	0.001870324	71	0.011410716574647888	2.539766	10	12	0.001623113	
GO Cellular Component	mitochondrial small ribosomal subunit	139	0.00001126634	0.00014005924834532377	2.730998	25	0.003117207	76	0.014281508463157896	1.959248	18	28	0.002921604	
GO Cellular Component	cytosolic small ribosomal subunit	163	0.00005382554	0.000570616767607362	2.01661	39	0.004862843	86	0.017666201972093024	1.731659	25	44	0.004057783	
GO Cellular Component	U4 snRNP	197	0.0002102119	0.0018438891532994925	3.812426	11	0.001371571	107	0.04897268276635514	2.438176	8	10	0.001298491	
GO Cellular Component	fibrinogen complex	200	0.0002250488	0.0019444216319999999	2.521541	20	0.002493766	84	0.017570322514285714	2.709084	8	9	0.001298491	
GO Molecular Function	peroxisome proliferator activated receptor binding	11	1.699065e-19	6.521320390909092e-17	5.733342	44	0.005486284	71	0.01840602901971831	2.742948	9	10	0.001460802	
GO Molecular Function	structural constituent of ribosome	13	1.615978e-16	5.2481993199999995e-14	2.176819	140	0.01745636	15	0.0000013703142744	1.674364	89	162	0.01444571	
GO Molecular Function	unfolded protein binding	17	7.663255e-15	1.9031919182352943e-12	2.467146	96	0.01197007	83	0.03769091817108434	1.466356	51	106	0.008277877	
GO Molecular Function	rRNA binding	39	6.370773e-11	6.896770155384615e-9	3.019852	48	0.005985037	72	0.018736104269444446	1.676246	33	60	0.005356273	
GO Molecular Function	ubiquitin-protein transferase regulator activity	50	2.110282e-9	1.7819221208e-7	2.892092	43	0.005361596	68	0.017644948720588235	2.330609	13	17	0.002110047	
Human Phenotype	Dysphonia	8	4.909117e-22	4.094817217625e-19	4.607787	62	0.007730673	103	0.02176367204660194	2.120153	16	23	0.002596981	
Human Phenotype	Hypoglycemia	21	3.188804e-17	1.013280432952381e-14	2.208342	142	0.01770574	70	0.0032730864810000004	1.564316	58	113	0.009414056	
Human Phenotype	Dyspnea	27	4.835463e-14	1.1950757258888888e-11	2.059087	133	0.01658354	138	0.046841587708695655	1.47673	47	97	0.007628632	
Human Phenotype	Respiratory distress	67	7.434454e-10	7.404494260000001e-8	2.072473	87	0.01084788	114	0.02800206209122807	1.648766	33	61	0.005356273	
Human Phenotype	Leukodystrophy	141	2.469305e-7	0.000011686292386524824	2.196853	53	0.006608479	93	0.015397351952688172	1.767677	29	50	0.004707028	
Human Phenotype	Mildly elevated creatine phosphokinase	172	0.000001367778	0.000053065015081395355	2.940373	27	0.003366584	125	0.038967560047200006	2.133404	14	20	0.002272358	
Mouse Phenotype	extramedullary hematopoiesis	1	8.850373e-49	8.4618416253e-45	2.566513	316	0.0394015	108	0.003422395361111111	1.44549	83	175	0.01347184	
Mouse Phenotype	dry eyes	37	6.299663e-18	1.6278669714324323e-15	3.87938	60	0.007481297	195	0.032877807849230764	2.28579	12	16	0.001947736	
Mouse Phenotype	early cellular replicative senescence	205	1.134562e-8	5.291486479024391e-7	2.0048	81	0.01009975	177	0.027707086583050846	1.586484	38	73	0.00616783