# GREAT version 4.0.4 Species assembly: hg38 Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included # Ontology Term Name Binom Rank Binom Raw P-Value Binom FDR Q-Val Binom Fold Enrichment Binom Observed Region Hits Binom Region Set Coverage Hyper Rank Hyper FDR Q-Val Hyper Fold Enrichment Hyper Observed Gene Hits Hyper Total Genes Hyper Gene Set Coverage GO Biological Process epithelial fluid transport 238 0.0004699545 0.02598374481302521 2.592589 17 0.002619414 743 0.04074524068775235 2.671959 7 8 0.001138396 Human Phenotype Abnormality of the 5th toe 1 1.979179e-10 0.0000013207061467 2.602633 58 0.008936826 37 0.020881836935135133 2.375075 14 18 0.002276793 Human Phenotype Preaxial foot polydactyly 42 0.000005151823 0.0008185265447380952 3.021005 23 0.003543914 65 0.04727998104461538 2.544723 10 12 0.001626281 Mouse Phenotype Single KO abnormal vestibuloocular reflex 39 0.000003471599 0.0008151136421282051 2.316814 38 0.005855162 813 0.025912271356703567 2.671959 7 8 0.001138396 Mouse Phenotype Single KO thick embryonic epiblast 157 0.0002669159 0.01556782736496815 4.017742 10 0.001540832 712 0.015835436741573033 3.053667 6 6 0.0009757684 Mouse Phenotype Single KO abnormal thymocyte activation 186 0.0004768964 0.023478173843010753 2.175399 24 0.003697997 514 0.005465920191050583 2.250071 14 19 0.002276793 Mouse Phenotype Single KO absent Schlemm's canal 202 0.0005630345 0.02552330156683168 2.639342 16 0.002465331 929 0.0370811975737352 3.053667 5 5 0.0008131403 Mouse Phenotype Single KO dilated rete testis 244 0.0008639811 0.032424077593032785 2.626274 15 0.002311248 712 0.015835436741573033 3.053667 6 6 0.0009757684 Mouse Phenotype Single KO abnormal liver bud morphology 258 0.001004911 0.03566655049224806 2.023875 25 0.00385208 813 0.025912271356703567 2.671959 7 8 0.001138396 Mouse Phenotype Single KO abnormal head fold morphology 303 0.001550182 0.04684823951815181 2.061751 22 0.003389831 739 0.017427505749661707 2.348975 10 13 0.001626281 Mouse Phenotype dilated rete testis 72 0.00001616053 0.002145983712916667 2.974488 21 0.003235747 869 0.009259114450632912 2.714371 8 9 0.001301025 Mouse Phenotype abnormal rete testis morphology 166 0.0001812713 0.01044057168253012 2.330517 24 0.003697997 768 0.005733391836328125 2.544723 10 12 0.001626281 Mouse Phenotype thick embryonic epiblast 189 0.0002669159 0.013502555131746032 4.017742 10 0.001540832 946 0.01244425801268499 3.053667 6 6 0.0009757684 Mouse Phenotype fused carpal bones 254 0.0005847801 0.022012135968897634 2.009104 28 0.00431433 1186 0.027724183257166947 2.099396 11 16 0.001788909 Mouse Phenotype abnormal peritoneum morphology 275 0.0008037091 0.02794277347309091 2.550256 16 0.002465331 1429 0.04955980145206438 2.375075 7 9 0.001138396 Mouse Phenotype abnormal MHC II cell surface expression on macrophages 289 0.0009569579 0.03165908125224914 3.16653 11 0.001694915 869 0.009259114450632912 2.714371 8 9 0.001301025 Mouse Phenotype abnormal liver bud morphology 294 0.001004911 0.0326801158877551 2.023875 25 0.00385208 1053 0.020889005364672364 2.671959 7 8 0.001138396