# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	ncRNA metabolic process	6	2.804742e-30	6.1512666630000006e-27	2.009292	319	0.06132257	58	2.6283287465517244e-8	1.499289	198	555	0.04431513	
GO Biological Process	nuclear-transcribed mRNA catabolic process	11	1.223564e-22	1.4637162432727273e-19	2.536504	144	0.02768166	100	0.0000035989970272	1.740451	82	198	0.01835273	
GO Biological Process	rRNA processing	17	2.376074e-20	1.8392210450588235e-17	2.301684	155	0.02979623	109	0.000006890111555137615	1.634326	98	252	0.02193375	
GO Biological Process	mRNA catabolic process	19	5.198637e-20	3.600466541210527e-17	2.34147	147	0.02825836	129	0.000024924176278294578	1.657344	84	213	0.01880036	
GO Biological Process	rRNA metabolic process	20	7.491365e-20	4.928943601749999e-17	2.258384	157	0.0301807	111	0.000007565668653873874	1.622607	100	259	0.02238138	
GO Biological Process	RNA catabolic process	21	1.388266e-19	8.699139187619047e-17	2.210333	162	0.03114187	107	0.0000051886182962616816	1.656607	95	241	0.02126231	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	24	4.940306e-18	2.7087286105833334e-15	3.004225	85	0.01633987	143	0.00008958208259930069	1.851972	52	118	0.01163832	
GO Biological Process	liver regeneration	34	2.861121e-16	1.1073379776176471e-13	3.754218	56	0.01076509	222	0.005749432650990991	2.281385	19	35	0.004252462	
GO Biological Process	viral gene expression	42	1.280468e-15	4.0118281933333336e-13	2.720826	85	0.01633987	96	0.0000025127302402083334	1.952366	59	127	0.01320501	
GO Biological Process	multi-organism metabolic process	44	3.790265e-15	1.133547662159091e-12	2.439187	100	0.01922338	84	8.481968691190477e-7	1.915449	67	147	0.01499552	
GO Biological Process	regulation of DNA-templated transcription in response to stress	47	5.541403e-15	1.5514749378085106e-12	2.436462	99	0.01903114	277	0.020245748571480145	1.5892	45	119	0.01007162	
GO Biological Process	protein localization to endoplasmic reticulum	49	6.74325e-15	1.810906668367347e-12	2.587389	88	0.01691657	157	0.00020107463273248412	1.796252	53	124	0.01186213	
GO Biological Process	translational initiation	50	7.405552e-15	1.94899317536e-12	2.463873	96	0.01845444	126	0.00001969371762539683	1.822085	62	143	0.01387645	
GO Biological Process	IRE1-mediated unfolded protein response	53	1.719028e-14	4.268054613584906e-12	3.540277	53	0.01018839	324	0.037063281995061724	1.811445	25	58	0.005595345	
GO Biological Process	cotranslational protein targeting to membrane	54	1.876228e-14	4.572089676296297e-12	2.933425	69	0.01326413	108	0.000006001283792592593	2.058393	48	98	0.01074306	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	58	2.670803e-14	6.059499427068965e-12	2.995964	66	0.01268743	120	0.000014751195136666665	2.055596	45	92	0.01007162	
GO Biological Process	protein targeting to ER	61	7.052781e-14	1.5214351668688522e-11	2.824602	70	0.01345636	147	0.00011782138918367346	1.914033	46	101	0.01029543	
GO Biological Process	viral transcription	64	2.220483e-13	4.56552121828125e-11	2.625354	76	0.01460977	125	0.0000193153802504	1.933917	52	113	0.01163832	
GO Biological Process	tRNA metabolic process	67	4.95007e-13	9.722085243283582e-11	2.100275	116	0.02229912	270	0.01707651715296296	1.467558	66	189	0.01477171	
GO Biological Process	establishment of protein localization to endoplasmic reticulum	68	5.248483e-13	1.0156586440735293e-10	2.617262	74	0.0142253	139	0.00006463823869784173	1.921166	48	105	0.01074306	
GO Cellular Component	ribosomal subunit	26	9.778839e-15	6.499166843076922e-13	2.331724	106	0.02037678	44	0.0002463210981818182	1.612871	71	185	0.01589078	
GO Cellular Component	ribosome	27	4.539627e-14	2.9053612799999994e-12	2.056179	133	0.02556709	34	0.000006400349364705883	1.638283	92	236	0.02059087	
GO Cellular Component	spliceosomal complex	28	1.070276e-13	6.605131885714286e-12	2.063218	128	0.02460592	38	0.00003788733675789474	1.671983	74	186	0.01656222	
GO Cellular Component	catalytic step 2 spliceosome	30	1.524107e-12	8.77885632e-11	2.557619	74	0.0142253	57	0.002393584976842105	1.751063	40	96	0.008952551	
GO Cellular Component	proteasome complex	44	1.1879e-8	4.665207272727273e-7	2.552781	48	0.00922722	88	0.04964060945454545	1.66866	27	68	0.006042972	
GO Cellular Component	small ribosomal subunit	57	1.18817e-7	0.0000036020311578947364	2.437799	45	0.008650519	59	0.0027149975755932205	1.867801	32	72	0.007162041	
GO Cellular Component	cytosolic small ribosomal subunit	66	0.000001098647	0.000028764576	2.630724	33	0.006343714	52	0.0013499544738461537	2.196788	23	44	0.005147717	
GO Cellular Component	preribosome	73	0.000005297538	0.00012539925567123288	2.126204	44	0.008458285	73	0.017618775583561643	1.714199	31	76	0.006938227	
GO Cellular Component	DNA-directed RNA polymerase III complex	79	0.00000867953	0.00018985098531645568	4.597439	13	0.002499039	80	0.03191454	2.433056	11	19	0.002461952	
GO Cellular Component	cytoplasmic stress granule	89	0.00002338883	0.00045411121617977535	2.171466	36	0.006920415	69	0.007571705321739131	2.052409	21	43	0.00470009	
GO Molecular Function	exonuclease activity	11	1.235605e-12	4.742476645454546e-10	2.744146	66	0.01268743	54	0.02456806819259259	1.769495	32	76	0.007162041	
GO Molecular Function	structural constituent of ribosome	14	4.459532e-12	1.3448674359999997e-9	2.229366	93	0.01787774	17	0.00029768204411764705	1.712151	66	162	0.01477171	
GO Molecular Function	deoxyribonucleotide binding	15	5.368188e-12	1.5109659824000001e-9	18.76116	12	0.002306805	70	0.04593184970857143	4.202551	5	5	0.001119069	
GO Molecular Function	ribonucleoprotein complex binding	26	3.635066e-10	5.9027879430769235e-8	2.245038	75	0.01441753	27	0.005539004425185185	1.717565	47	115	0.01051925	
GO Molecular Function	rRNA binding	28	1.23571e-9	1.8632741500000002e-7	3.394818	35	0.006728181	69	0.040317621869565216	1.821106	26	60	0.005819158	
GO Molecular Function	NF-kappaB binding	31	1.332389e-8	0.0000018146278574193549	3.358449	31	0.005959246	67	0.04009068156119403	2.251367	15	28	0.003357207	
GO Molecular Function	mismatched DNA binding	56	0.000005102229	0.0003846716221071429	4.496391	14	0.002691273	51	0.02155800387058824	3.151914	9	12	0.002014324	
GO Molecular Function	signal sequence binding	72	0.000008731703	0.0005120173620277778	2.102692	43	0.008266052	68	0.040700738135294116	1.961191	21	45	0.00470009	
Human Phenotype	Basal cell carcinoma	39	0.000001443889	0.0002470531101794872	3.17097	24	0.00461361	6	0.014300239	2.865376	15	22	0.003357207	
Mouse Phenotype Single KO	pale liver	25	1.038756e-10	3.8047554768e-8	2.358123	72	0.01384083	53	0.02880823299245283	1.786084	34	80	0.007609669	
Mouse Phenotype Single KO	abnormal circulating glucagon level	52	8.658532e-8	0.000015247341831538461	2.08881	64	0.01230296	63	0.03712891696984127	2.158067	19	37	0.004252462	
Mouse Phenotype Single KO	increased circulating glucagon level	239	0.0005521982	0.021156815553974896	2.151683	24	0.00461361	27	0.0023116012195555555	3.213716	13	17	0.002909579