# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	blood coagulation	10	7.631304e-16	1.0042032933599999e-12	2.151671	134	0.0554177	3	0.00005689977918	1.88511	78	306	0.03072076	
GO Biological Process	coagulation	11	8.236814e-16	9.853475947818182e-13	2.149464	134	0.0554177	5	0.00004636060449	1.872869	78	308	0.03072076	
GO Biological Process	hemostasis	12	1.396052e-15	1.5308873556666665e-12	2.134225	134	0.0554177	7	0.00005197530540857143	1.854803	78	311	0.03072076	
GO Biological Process	regulation of gene expression, epigenetic	18	1.193292e-14	8.72362746e-12	2.484094	92	0.03804797	66	0.006423605725757576	1.699756	57	248	0.02244978	
GO Biological Process	gene silencing	26	1.449346e-13	7.335363082307692e-11	2.816656	68	0.02812242	73	0.009686812181917808	1.807772	44	180	0.01732966	
GO Biological Process	chromatin silencing	44	1.142096e-11	3.415645741818182e-9	4.054632	35	0.01447477	135	0.03705655303481482	1.982281	26	97	0.01024025	
GO Biological Process	negative regulation of gene expression, epigenetic	47	1.266449e-11	3.5457877427659574e-9	3.360384	44	0.01819686	65	0.006520677245538462	2.075911	32	114	0.01260339	
GO Biological Process	mRNA splicing, via spliceosome	54	5.678671e-11	1.3838079942407408e-8	2.063527	98	0.04052936	94	0.021558487692553193	1.582882	61	285	0.02402521	
GO Biological Process	RNA splicing, via transesterification reactions	56	6.566368e-11	1.5429792234285716e-8	2.057808	98	0.04052936	107	0.0255905163682243	1.566393	61	288	0.02402521	
GO Biological Process	negative regulation of intrinsic apoptotic signaling pathway	73	4.349236e-10	7.839944729315068e-8	2.909611	46	0.01902399	112	0.02600828178660714	2.045545	26	94	0.01024025	
GO Biological Process	nuclear membrane organization	102	1.041626e-8	0.0000013437996601960786	20.20967	8	0.003308519	117	0.026981348564102565	6.162859	5	6	0.001969279	
GO Biological Process	regulation of hematopoietic progenitor cell differentiation	157	1.773688e-7	0.000014866216810191084	2.708785	36	0.01488834	138	0.038270939507971016	1.897943	29	113	0.01142182	
GO Biological Process	ER-nucleus signaling pathway	342	0.00004014318	0.001544573408245614	3.077778	18	0.007444169	137	0.03791464249562044	2.746874	13	35	0.005120126	
GO Biological Process	regulation of histone ubiquitination	362	0.00005579057	0.0020280334547790055	6.274431	8	0.003308519	130	0.035798765953076926	4.930288	6	9	0.002363135	
GO Cellular Component	nuclear nucleosome	48	3.113958e-8	0.00000112102488	6.372021	15	0.006203474	64	0.045205911	2.403515	13	40	0.005120126	
GO Cellular Component	nucleosome	55	2.908435e-7	0.000009137773963636364	3.186777	27	0.01116625	43	0.004085831888372093	2.042548	29	105	0.01142182	
GO Cellular Component	DNA packaging complex	76	0.00000461764	0.00010499055157894736	2.683203	28	0.01157982	47	0.005244134399999999	1.980919	30	112	0.01181568	
GO Cellular Component	transcriptional repressor complex	77	0.000005324717	0.00011949494774025974	2.080531	46	0.01902399	49	0.00642881946122449	2.138438	24	83	0.00945254	
GO Molecular Function	protein serine/threonine kinase inhibitor activity	24	4.606973e-8	0.000008104433335833334	3.409182	28	0.01157982	14	0.0129731505	3.137456	14	33	0.005513982	
GO Molecular Function	protein kinase inhibitor activity	26	1.734266e-7	0.000028161811738461543	2.080599	61	0.02522746	9	0.0061875849377777785	2.257553	29	95	0.01142182	
GO Molecular Function	kinase inhibitor activity	29	3.55797e-7	0.00005179913565517242	2.035246	61	0.02522746	12	0.011025109144999998	2.166338	29	99	0.01142182	
GO Molecular Function	phosphotyrosine binding	35	9.082656e-7	0.00010956278180571428	2.863733	29	0.01199338	37	0.04504236135675676	2.746874	13	35	0.005120126	
GO Molecular Function	nucleosomal DNA binding	50	0.000005290865	0.0004467606406	3.204575	21	0.008684864	32	0.02797714896875	2.572324	16	46	0.006301694	
GO Molecular Function	nucleosome binding	73	0.00002433031	0.0014071584769863013	2.490504	27	0.01116625	35	0.037377136805714285	2.24104	20	66	0.007877117	
Mouse Phenotype Single KO	increased susceptibility to age-related hearing loss	392	0.0004766987	0.011135535703826529	2.586048	17	0.007030604	37	0.04210242582972973	3.521634	10	21	0.003938558	
Mouse Phenotype	extramedullary hematopoiesis	65	9.572507e-11	1.4080421450307692e-8	2.208962	82	0.03391232	68	0.03561596230588235	1.732644	41	175	0.01614809	
Mouse Phenotype	decreased pre-B cell number	102	4.162714e-9	3.90193221117647e-7	2.233028	66	0.02729529	45	0.017921406108000002	2.062188	29	104	0.01142182	
Mouse Phenotype	abnormal pre-B cell morphology	112	8.733108e-9	7.455111213214285e-7	2.070051	75	0.03101737	43	0.013753983220465114	1.946166	35	133	0.01378495	
Mouse Phenotype	abnormal megakaryocyte progenitor cell morphology	173	5.91734e-7	0.000032702709676300574	2.030305	59	0.02440033	25	0.0038803777428	2.104391	35	123	0.01378495	
Mouse Phenotype	decreased erythroid progenitor cell number	208	0.000003281068	0.00015081870744230772	2.120996	46	0.01902399	51	0.02172562902352941	2.238091	23	76	0.009058685	
Mouse Phenotype	increased susceptibility to age-related hearing loss	482	0.0006489153	0.012871948513070539	2.310528	20	0.008271299	39	0.013636800366153846	3.413276	12	26	0.00472627