# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	5	1.700921e-18	4.4764838878e-15	3.363631	74	0.02322662	189	0.009688943850264552	1.870767	34	113	0.01125828	
GO Biological Process	regulation of cellular amino acid metabolic process	8	9.691737e-18	1.5941695897874998e-14	5.234665	43	0.01349655	266	0.03785181897706767	2.072517	20	60	0.006622517	
GO Biological Process	regulation of hematopoietic stem cell differentiation	14	8.364595e-17	7.862121828928572e-14	3.746579	58	0.01820465	215	0.01633844697767442	1.871301	31	103	0.0102649	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to hypoxia	15	1.450899e-16	1.2728253294e-13	3.751474	57	0.01789077	113	0.001875450957345133	2.231941	28	78	0.009271523	
GO Biological Process	regulation of mRNA stability	16	2.692202e-16	2.2141678823749997e-13	2.627872	94	0.02950408	144	0.003453590515833333	1.811736	44	151	0.01456954	
GO Biological Process	regulation of hematopoietic progenitor cell differentiation	17	3.520345e-16	2.724954109117647e-13	3.483472	61	0.01914626	262	0.03544646359274809	1.760722	32	113	0.01059603	
GO Biological Process	regulation of DNA-templated transcription in response to stress	20	9.594734e-16	6.3128552353e-13	2.973588	74	0.02322662	230	0.023427740076086955	1.776443	34	119	0.01125828	
GO Biological Process	regulation of RNA stability	27	9.675742e-15	4.715669962148148e-12	2.471512	94	0.02950408	196	0.011180282512755104	1.709826	44	160	0.01456954	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	28	3.327872e-14	1.5639809874285715e-11	3.289372	57	0.01789077	160	0.0053805497900625	1.89688	36	118	0.01192053	
GO Biological Process	mRNA catabolic process	29	4.519446e-14	2.0507375832413792e-11	2.418682	93	0.02919021	198	0.011515374440404041	1.605471	55	213	0.01821192	
GO Biological Process	anaphase-promoting complex-dependent catabolic process	35	1.505437e-13	5.660012995142856e-11	3.433691	51	0.01600753	166	0.006229715547650603	2.098423	27	80	0.008940397	
GO Biological Process	RNA catabolic process	38	2.677826e-13	9.273029561578946e-11	2.250032	101	0.03170119	146	0.003714054744589041	1.625335	63	241	0.02086093	
GO Biological Process	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	39	3.04259e-13	1.026601072051282e-10	3.710786	45	0.01412429	254	0.03277581551496063	1.986162	23	72	0.007615894	
GO Biological Process	nuclear-transcribed mRNA catabolic process	41	3.171674e-13	1.017952638195122e-10	2.444649	85	0.02667922	244	0.031304112284016396	1.570088	50	198	0.01655629	
GO Biological Process	regulation of ubiquitin protein ligase activity	42	3.565729e-13	1.1171768550238096e-10	3.306246	52	0.01632141	197	0.011522414502030459	1.95988	29	92	0.009602649	
GO Biological Process	negative regulation of ubiquitin protein ligase activity	43	4.951834e-13	1.5153763629302323e-10	3.593747	46	0.01443817	264	0.03615869895757576	1.937938	24	77	0.00794702	
GO Biological Process	positive regulation of ubiquitin protein ligase activity	44	6.371998e-13	1.9056618564090909e-10	3.348444	50	0.01569366	203	0.012894912482758621	1.998498	27	84	0.008940397	
GO Biological Process	negative regulation of ubiquitin-protein transferase activity	48	8.36839e-13	2.2941592502083333e-10	3.372668	49	0.01537979	235	0.028084564952340425	1.92448	26	84	0.008609272	
GO Biological Process	regulation of stem cell differentiation	53	1.37028e-12	3.4021725509433965e-10	2.32147	89	0.02793471	109	0.0016421333404587155	1.896132	43	141	0.01423841	
GO Biological Process	cotranslational protein targeting to membrane	60	7.318104e-12	1.6049821755999998e-9	3.262483	47	0.01475204	111	0.00166432661009009	2.093665	33	98	0.01092715	
GO Cellular Component	intracellular ribonucleoprotein complex	11	6.014132e-33	9.447654632727273e-31	2.044757	325	0.1020088	21	1.7455688228571428e-8	1.520015	199	814	0.06589404	
GO Cellular Component	ribonucleoprotein complex	12	7.52172e-33	1.08312768e-30	2.042153	325	0.1020088	19	1.5352470568421055e-8	1.522044	200	817	0.06622517	
GO Cellular Component	ribosome	34	1.348482e-12	6.85346145882353e-11	2.297076	91	0.02856246	31	0.000064862208	1.765152	67	236	0.02218543	
GO Cellular Component	ribosomal subunit	36	1.125542e-11	5.402601599999999e-10	2.514165	70	0.02197112	37	0.0005141304389189189	1.781244	53	185	0.01754967	
GO Cellular Component	mitochondrial ribosome	38	1.320382e-11	6.004263410526316e-10	3.767094	38	0.01192718	51	0.00838236197647059	1.974986	27	85	0.008940397	
GO Cellular Component	mitochondrial large ribosomal subunit	46	1.246544e-9	4.682669634782609e-8	4.336482	26	0.008160703	56	0.019829574514285714	2.194429	18	51	0.005960265	
GO Cellular Component	large ribosomal subunit	52	3.898596e-7	0.0000129553344	2.441449	41	0.0128688	61	0.027710995514754096	1.730101	32	115	0.01059603	
GO Cellular Component	PcG protein complex	59	0.000001112143	0.00003257259498305085	2.58212	34	0.01067169	52	0.016253199138461537	2.29779	17	46	0.005629139	
GO Cellular Component	small ribosomal subunit	65	0.000002720856	0.00007233291027692308	2.653574	30	0.009416196	63	0.04342603885714286	1.899807	22	72	0.007284768	
GO Molecular Function	cadherin binding	3	5.295609e-22	7.452687066e-19	2.177503	187	0.05869429	7	2.215296669142857e-7	1.881627	92	304	0.03046358	
GO Molecular Function	structural constituent of ribosome	34	9.082489e-9	0.0000011278314281764705	2.309271	59	0.01851852	24	0.00909021932	1.765477	46	162	0.01523179	
GO Molecular Function	deoxyribonucleotide binding	35	9.640799e-9	0.0000011629558108	20.42176	8	0.002510986	27	0.016782262355555556	6.21755	5	5	0.001655629	
Mouse Phenotype	abnormal adrenal chromaffin cell morphology	61	6.024561e-7	0.00009442758642786887	4.020237	19	0.005963591	31	0.043367462322580645	3.73053	9	15	0.002980132	
Mouse Phenotype	abnormal neuroendocrine cell morphology	67	0.000001130802	0.00016136713316417913	2.897419	28	0.008788449	18	0.001568064553	3.626904	14	24	0.004635762	
Mouse Phenotype	abnormal adrenal medulla morphology	72	0.000001643108	0.00021819104983333335	3.143776	24	0.007532957	23	0.025418691693913042	3.108775	13	26	0.004304636	
