# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	negative regulation of gene expression, epigenetic	12	4.077815e-28	4.471663965416667e-25	3.883962	97	0.02103209	174	0.00047743037604022987	1.806697	48	114	0.01096892	
GO Biological Process	regulation of gene expression, epigenetic	15	2.095308e-27	1.8381438648e-24	2.519806	178	0.03859497	59	1.0439416087966102e-8	1.799412	104	248	0.023766	
GO Biological Process	DNA conformation change	16	1.053453e-25	8.663992516874999e-23	2.285496	201	0.04358196	101	0.000002143005687821782	1.633903	107	281	0.02445155	
GO Biological Process	chromatin silencing	17	2.026623e-25	1.568725415117647e-22	4.494508	74	0.0160451	236	0.0035503422491949153	1.769445	40	97	0.009140768	
GO Biological Process	nucleosome organization	24	3.761722e-22	2.0625208249166665e-19	2.661168	129	0.02797051	124	0.00002142398749435484	1.756511	70	171	0.01599634	
GO Biological Process	chromatin assembly	25	4.197257e-22	2.20926819452e-19	2.720136	124	0.02688638	111	0.000008801080622702702	1.819561	67	158	0.01531079	
GO Biological Process	viral transcription	27	4.494275e-21	2.1903764712962962e-18	3.35084	86	0.01864701	104	0.000003890045865961539	2.012548	53	113	0.01211152	
GO Biological Process	chromatin assembly or disassembly	28	8.358725e-21	3.9283022241071424e-18	2.53955	131	0.02840416	135	0.000052744722582222215	1.711541	71	178	0.01622486	
GO Biological Process	ncRNA processing	30	1.14504e-20	5.02252712e-18	2.055169	202	0.04379879	103	0.000003817180606019418	1.516987	140	396	0.03199269	
GO Biological Process	viral gene expression	31	1.294545e-20	5.495134727419355e-18	3.213312	89	0.01929748	123	0.000019021152627642275	1.892053	56	127	0.01279707	
GO Biological Process	DNA packaging	32	1.810154e-20	7.443692651875e-18	2.418866	141	0.03057242	121	0.00001756412206528926	1.703425	79	199	0.01805302	
GO Biological Process	nucleosome assembly	33	1.835003e-20	7.317213477878789e-18	2.75108	112	0.02428448	130	0.00004095078775538462	1.813058	60	142	0.01371115	
GO Biological Process	DNA replication-dependent nucleosome assembly	34	4.486708e-20	1.7364879579999998e-17	13.56848	25	0.005420642	376	0.03114315681888298	2.145452	16	32	0.003656307	
GO Biological Process	gene silencing	35	5.104547e-20	1.9191638278e-17	2.605992	120	0.02601908	169	0.000321908383408284	1.644847	69	180	0.01576782	
GO Biological Process	RNA catabolic process	36	6.852711e-20	2.5048562235833334e-17	2.308421	150	0.03252385	76	9.217039748026316e-8	1.762654	99	241	0.0226234	
GO Biological Process	multi-organism metabolic process	39	2.419288e-19	8.162925844102563e-17	2.80625	102	0.02211622	114	0.00001301383545263158	1.838959	63	147	0.01439671	
GO Biological Process	regulation of gene silencing	42	4.351509e-19	1.3633692126428573e-16	2.781603	102	0.02211622	106	0.000004132269871981132	1.932545	59	131	0.01348263	
GO Biological Process	RNA splicing, via transesterification reactions	43	5.631474e-19	1.723362008511628e-16	2.047664	186	0.04032958	47	7.281401059999999e-10	1.787877	120	288	0.0274223	
GO Biological Process	mRNA catabolic process	44	1.400667e-18	4.188949330227273e-16	2.371517	132	0.02862099	80	2.3364265065e-7	1.792913	89	213	0.02033821	
GO Biological Process	mRNA splicing, via spliceosome	45	3.948872e-18	1.154737925511111e-15	2.020237	183	0.0396791	56	3.6322834696428575e-9	1.761529	117	285	0.02673675	
GO Cellular Component	nucleosome	21	6.84504e-26	5.6324900571428575e-24	4.579169	74	0.0160451	34	0.0000020651017976470586	2.043288	50	105	0.01142596	
GO Cellular Component	DNA packaging complex	22	2.336077e-24	1.8348822981818183e-22	4.019318	80	0.01734605	35	0.0000031012998582857143	1.992206	52	112	0.011883	
GO Cellular Component	ribosome	29	1.400733e-17	8.346436634482757e-16	2.301783	132	0.02862099	52	0.00011112532061538461	1.563635	86	236	0.01965265	
GO Cellular Component	ribosomal subunit	32	2.857412e-17	1.54300248e-15	2.580392	104	0.02254987	60	0.000353776608	1.600392	69	185	0.01576782	
GO Cellular Component	nuclear nucleosome	33	3.39096e-17	1.7756299636363636e-15	7.126937	32	0.006938422	105	0.033380039314285716	1.930907	18	40	0.004113346	
GO Cellular Component	protein-DNA complex	39	6.891975e-14	3.053675076923077e-12	2.133092	120	0.02601908	36	0.00000325990608	1.72061	81	202	0.01851005	
GO Cellular Component	mitochondrial membrane part	43	8.54367e-13	3.4333631999999996e-11	2.080334	116	0.02515178	59	0.00035619908338983055	1.558489	77	212	0.01759598	
GO Cellular Component	cytosolic ribosome	44	1.203018e-12	4.7245797818181814e-11	2.496679	78	0.0169124	53	0.00011394226596226415	1.838959	48	112	0.01096892	
GO Cellular Component	chromosome, telomeric region	46	1.702468e-12	6.395358052173913e-11	2.317457	89	0.01929748	71	0.001876867930140845	1.567337	61	167	0.01393967	
GO Cellular Component	large ribosomal subunit	51	3.838393e-11	1.3005378635294119e-9	2.591557	63	0.01366002	97	0.016780248148453608	1.567113	42	115	0.009597806	
GO Cellular Component	nuclear chromosome, telomeric region	56	5.08002e-10	1.5675490285714285e-8	2.316102	69	0.01496097	83	0.004993799248192771	1.592836	49	132	0.01119744	
GO Cellular Component	intrinsic component of endoplasmic reticulum membrane	58	5.665096e-10	1.687807911724138e-8	2.080392	87	0.01886383	80	0.0041121864	1.582461	52	141	0.011883	
GO Cellular Component	mitochondrial intermembrane space	63	2.609821e-9	7.158366171428571e-8	2.682571	48	0.01040763	76	0.003430289178947368	1.815383	33	78	0.007541133	
GO Cellular Component	integral component of endoplasmic reticulum membrane	65	4.584506e-9	1.2187732873846153e-7	2.024414	83	0.01799653	85	0.0067803284329411755	1.566024	50	137	0.01142596	
GO Cellular Component	cytosolic large ribosomal subunit	67	5.493002e-9	1.4167026053731343e-7	2.79297	43	0.009323504	84	0.004969285714285714	1.899253	27	61	0.006170018	
GO Cellular Component	small ribosomal subunit	70	1.093576e-8	2.6995704685714286e-7	2.688556	44	0.00954033	106	0.035867411320754716	1.668685	28	72	0.006398537	
GO Cellular Component	intrinsic component of mitochondrial membrane	72	1.768035e-8	4.243284e-7	2.577538	46	0.009973981	61	0.00040226055344262294	2.046432	31	65	0.007084095	
GO Cellular Component	integral component of mitochondrial membrane	75	3.824213e-8	8.810986752e-7	2.539086	45	0.009757155	66	0.0007743992727272727	2.011362	30	64	0.006855576	
GO Cellular Component	inner mitochondrial membrane protein complex	80	1.050138e-7	0.00000226829808	2.002087	70	0.0151778	91	0.012274912562637363	1.534703	49	137	0.01119744	
GO Cellular Component	intrinsic component of mitochondrial outer membrane	81	1.115856e-7	0.0000023804927999999996	3.9486	22	0.004770165	90	0.011596606079999999	2.425294	13	23	0.00297075	
GO Molecular Function	structural constituent of ribosome	9	1.655318e-17	7.765280662222223e-15	2.676792	99	0.02146574	24	0.0004958135605833333	1.695172	64	162	0.01462523	
GO Molecular Function	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	84	0.000161159	0.008100158309523809	2.301948	25	0.005420642	48	0.026311275308333337	2.145452	19	38	0.004341865	
GO Molecular Function	endoribonuclease activity, producing 5'-phosphomonoesters	133	0.000853111	0.02708146347368421	2.209354	21	0.004553339	44	0.019951032213636366	2.367396	16	29	0.003656307	
Human Phenotype	Increased serum lactate	3	1.361753e-12	3.028992589666667e-9	2.712202	67	0.01452732	32	0.01266101655	1.759271	41	100	0.009369287	
Human Phenotype	Hypoketotic hypoglycemia	92	0.0004479018	0.03248748599347826	6.333565	6	0.001300954	41	0.026007675712195123	4.290905	6	6	0.001371115	
Mouse Phenotype	decreased pre-B cell number	2	6.425998e-19	3.0719483438999998e-15	2.376961	134	0.02905464	15	0.00005371694874	2.021676	49	104	0.01119744	
Mouse Phenotype	abnormal pre-B cell morphology	5	1.317644e-14	2.5195988568000003e-11	2.040356	141	0.03057242	20	0.00129106437645	1.774434	55	133	0.01256856