# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	gland development	112	7.86991e-122	9.246441579464286e-120	3.740741	424	0.2081492	52	0.000027149142684615388	2.09742	56	396	0.04423381	
GO Biological Process	chordate embryonic development	114	1.224585e-120	1.4135363171052633e-118	3.358862	474	0.2326951	65	0.00011838148167076923	1.843948	69	555	0.05450237	
GO Biological Process	embryo development ending in birth or egg hatching	118	9.109595e-120	1.0158742424152543e-117	3.340069	474	0.2326951	68	0.00015737060966176472	1.827484	69	560	0.05450237	
GO Biological Process	regulation of epithelial cell proliferation	128	2.38578e-114	2.4526936734375e-112	4.180163	356	0.1747668	175	0.025041441650285715	1.828572	36	292	0.02843602	
GO Biological Process	macromolecular complex subunit organization	139	8.18333e-102	7.747081976258992e-100	2.122835	777	0.3814433	54	0.0000361661956	1.402913	208	2199	0.164297	
GO Biological Process	negative regulation of signal transduction	162	1.835892e-86	1.4912656066666668e-84	2.318006	589	0.2891507	125	0.006334098335359999	1.434505	112	1158	0.08846761	
GO Biological Process	negative regulation of cell communication	173	7.768347e-76	5.908883131387283e-74	2.151253	599	0.2940599	119	0.004258061096890756	1.426584	121	1258	0.09557662	
GO Biological Process	negative regulation of signaling	174	1.341633e-75	1.0146292325862069e-73	2.148094	599	0.2940599	123	0.004737481783252033	1.422062	121	1262	0.09557662	
GO Biological Process	embryo development	191	2.311016e-64	1.592181127958115e-62	2.17134	512	0.25135	109	0.003419142809174312	1.524147	93	905	0.07345972	
GO Biological Process	endoplasmic reticulum unfolded protein response	301	2.579094e-27	1.1275182041860465e-25	5.163558	69	0.03387334	200	0.039837293419999996	2.341856	18	114	0.01421801	
GO Biological Process	positive regulation of endoplasmic reticulum unfolded protein response	302	4.647667e-27	2.0251208626821194e-25	10.43801	40	0.01963672	138	0.01005658457536232	6.845425	6	13	0.004739336	
GO Biological Process	regulation of endoplasmic reticulum unfolded protein response	318	4.271138e-24	1.7674183944025158e-22	8.331357	41	0.02012764	198	0.03889305940606061	4.514012	7	23	0.005529226	
GO Biological Process	in utero embryonic development	356	5.246778e-18	1.9393919017415731e-16	2.130214	156	0.07658321	50	0.000019398655666000002	2.274518	48	313	0.03791469	
GO Biological Process	response to endoplasmic reticulum stress	362	2.765201e-17	1.0051734795303867e-15	2.69751	95	0.04663721	164	0.01858386996402439	1.945148	32	244	0.02527646	
GO Biological Process	placenta development	370	1.77207e-16	6.302343008108108e-15	2.776852	86	0.04221895	122	0.0045301464623770495	2.438096	24	146	0.01895735	
GO Biological Process	embryonic placenta development	377	8.884001e-16	3.1009169538196285e-14	3.108775	69	0.03387334	87	0.0008979736388160919	3.166329	19	89	0.0150079	
GO Biological Process	chromatin silencing	395	4.938081e-13	1.6450685538987343e-11	4.675495	34	0.01669121	51	0.000021953846032156863	3.516808	23	97	0.01816746	
GO Biological Process	regulation of megakaryocyte differentiation	441	2.204761e-10	6.5787868478458046e-9	3.466114	37	0.01816397	117	0.0042823851062393165	3.122474	16	76	0.01263823	
GO Biological Process	regulation of hematopoietic progenitor cell differentiation	442	2.255472e-10	6.714876933936652e-9	3.394071	38	0.01865488	101	0.0024933256281188124	2.756344	21	113	0.01658768	
GO Biological Process	negative regulation of megakaryocyte differentiation	446	4.146794e-10	1.2234901848878925e-8	22.97222	9	0.004418262	137	0.009833029132116788	5.767904	7	18	0.005529226	
GO Cellular Component	nuclear chromatin	35	6.074463e-27	2.999049161142857e-25	2.704934	151	0.07412862	5	7.71918336e-10	2.722284	58	316	0.04581359	
GO Cellular Component	nuclear chromosome part	36	9.594156e-27	4.60519488e-25	2.330939	195	0.09572901	13	5.642470301538462e-8	2.135311	74	514	0.05845182	
GO Cellular Component	chromatin	42	1.062822e-23	4.372753371428571e-22	2.255246	184	0.09032892	6	1.239513984e-9	2.319369	76	486	0.0600316	
GO Cellular Component	nuclear chromosome	44	9.74395e-23	3.826714909090909e-21	2.148829	195	0.09572901	21	7.117910948571429e-7	1.995545	74	550	0.05845182	
GO Cellular Component	nucleosome	58	5.946581e-14	1.771671028965517e-12	4.90367	35	0.01718213	4	4.5728668800000003e-10	4.378899	31	105	0.02448657	
GO Cellular Component	nuclear nucleosome	60	5.236388e-13	1.508079744e-11	9.580867	19	0.009327442	27	0.0030042432	4.078732	11	40	0.008688784	
GO Cellular Component	DNA packaging complex	65	1.810396e-11	4.812868135384616e-10	3.981335	35	0.01718213	8	1.502837928e-9	4.105218	31	112	0.02448657	
GO Cellular Component	protein-DNA complex	78	1.819298e-8	4.0304448e-7	2.294043	57	0.02798233	17	2.0632543623529412e-7	2.863556	39	202	0.03080569	
GO Molecular Function	enzyme binding	14	1.089012e-96	3.284149045714286e-94	2.145959	733	0.3598429	12	0.00003316794052333333	1.447955	185	1895	0.1461295	
GO Molecular Function	hormone receptor binding	41	5.165851e-16	5.319566566341463e-14	2.651624	90	0.04418262	29	0.011234742	2.303067	25	161	0.01974724	
GO Molecular Function	nuclear hormone receptor binding	45	3.199176e-14	3.001538016e-12	2.651411	79	0.03878252	33	0.04292914247272727	2.27348	21	137	0.01658768	
GO Molecular Function	histone deacetylase binding	97	8.405667e-7	0.000036586315540206186	2.169734	49	0.02405498	31	0.042036506432258064	2.471959	18	108	0.01421801	
Mouse Phenotype Single KO	embryonic lethality during organogenesis	82	3.042008e-71	3.397032592195122e-69	2.490231	443	0.2174767	6	0.034820911835	1.592672	80	745	0.06319115	
Mouse Phenotype	decreased embryo size	114	1.119534e-104	9.389354889473684e-103	3.124619	455	0.2233677	18	0.015871902711666667	1.645323	69	622	0.05450237	
Mouse Phenotype	abnormal embryo size	124	1.764626e-97	1.3606120311290322e-95	2.890613	472	0.2317133	20	0.0163599179295	1.584763	78	730	0.06161137	
Mouse Phenotype	abnormal blood cell morphology	129	3.23426e-87	2.3971131674418604e-85	2.10318	699	0.3431517	30	0.02645885644	1.322425	167	1873	0.1319115	
Mouse Phenotype	abnormal prenatal body size	134	4.344349e-85	3.0997254320149252e-83	2.553682	499	0.2449681	21	0.016036551478571432	1.523352	91	886	0.07187994	
Mouse Phenotype	abnormal embryonic growth/weight/body size	149	1.26248e-75	8.10105455033557e-74	2.331712	520	0.2552774	12	0.012050381635000001	1.514353	102	999	0.08056872	
Mouse Phenotype	abnormal postnatal growth	165	2.221218e-65	1.2870948665454547e-63	2.146804	530	0.2601865	44	0.048203932725	1.425012	98	1020	0.07740916	
Mouse Phenotype	abnormal prenatal growth/weight/body size	169	6.193995e-62	3.5041885322485204e-60	2.062198	546	0.2680412	29	0.02714335590413793	1.418473	114	1192	0.09004739	
Mouse Phenotype	embryonic lethality during organogenesis	192	3.017187e-55	1.50246483890625e-53	2.100348	477	0.2341679	16	0.013998409490624999	1.512499	98	961	0.07740916	
Mouse Phenotype	abnormal hair follicle outer root sheath morphology	291	7.914757e-24	2.600446449381443e-22	7.008458	46	0.02258223	24	0.02384071602125	4.767349	9	28	0.007109005	
Mouse Phenotype	abnormal liver lobule morphology	343	7.667019e-17	2.137153605218659e-15	2.546601	102	0.05007364	26	0.02532407360769231	2.047899	33	239	0.02606635	
Mouse Phenotype	abnormal liver parenchyma morphology	366	6.550944e-15	1.7112998793442625e-13	2.34792	104	0.05105547	33	0.02909919322727273	1.985353	34	254	0.02685624	
Mouse Phenotype	abnormal enterocyte physiology	809	0.0003668294	0.004335297766872683	2.00961	30	0.01472754	34	0.02930612411470588	3.006437	15	74	0.01184834