# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	96	9.30629e-85	1.2756403136458333e-82	2.278071	717	0.01573058	288	0.000005176572405208333	1.218619	109	113	0.007333647	
GO Biological Process	regulation of DNA-templated transcription in response to stress	105	2.690933e-81	3.372379747333333e-79	2.162775	770	0.01689337	258	0.0000017255172282945736	1.220873	115	119	0.007737334	
GO Biological Process	endoplasmic reticulum unfolded protein response	114	2.276527e-78	2.6277911221929822e-76	2.257462	675	0.01480913	523	0.0011264151805162523	1.174683	106	114	0.007131804	
GO Biological Process	cellular response to topologically incorrect protein	137	1.762916e-70	1.69330012e-68	2.045178	760	0.01667398	424	0.0002689417178066038	1.172451	129	139	0.008679271	
GO Biological Process	cellular response to unfolded protein	143	4.467478e-68	4.1110169931468533e-66	2.084974	700	0.01535761	526	0.001205561785	1.169371	112	121	0.007535491	
GO Biological Process	positive regulation of transcription from RNA polymerase II promoter in response to stress	146	2.208806e-67	1.990799873561644e-65	3.609448	267	0.005857832	1012	0.047411772976284586	1.263338	24	24	0.001614748	
GO Biological Process	liver regeneration	194	8.885829e-58	6.027248650051546e-56	2.69321	352	0.007722685	962	0.03885461486486487	1.227243	34	35	0.00228756	
GO Biological Process	IRE1-mediated unfolded protein response	220	1.369519e-53	8.19159114590909e-52	2.614878	343	0.00752523	783	0.0148975459045977	1.197993	55	58	0.003700464	
GO Biological Process	regulation of mitochondrial membrane permeability	254	4.958236e-50	2.568717619055118e-48	2.070169	519	0.01138657	531	0.0012568388890207155	1.21142	70	73	0.004709682	
GO Biological Process	response to epidermal growth factor	256	1.058657e-49	5.4417451027343746e-48	2.16489	464	0.0101799	1035	0.04933977856908213	1.20318	40	42	0.002691247	
GO Biological Process	platelet-derived growth factor receptor signaling pathway	270	2.844128e-48	1.3861437167407408e-46	2.165293	450	0.009872751	709	0.008226318226093089	1.263338	33	33	0.002220279	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	282	3.301228e-47	1.5404560018439718e-45	2.04108	506	0.01110136	876	0.024340755098173513	1.134863	106	118	0.007131804	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to hypoxia	303	1.545928e-45	6.713817343894391e-44	2.097797	456	0.01000439	569	0.00230850279629174	1.198552	74	78	0.004978806	
GO Biological Process	cotranslational protein targeting to membrane	318	3.970414e-44	1.642977290125786e-42	2.110625	435	0.009543659	381	0.00007625823551706038	1.211774	94	98	0.00632443	
GO Biological Process	protein targeting to ER	355	3.518534e-41	1.3042363072112677e-39	2.03553	442	0.009697236	415	0.00020928133846024097	1.200797	96	101	0.006458992	
GO Biological Process	regulation of plasma lipoprotein particle levels	369	4.980249e-40	1.776018877804878e-38	2.001161	448	0.009828872	649	0.005068832606933744	1.194114	69	73	0.004642401	
GO Biological Process	plasma lipoprotein particle organization	389	1.411693e-38	4.775441693316195e-37	2.322416	306	0.006713471	948	0.03673688810443038	1.205914	42	44	0.002825809	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	399	9.099956e-38	3.0011609274185465e-36	2.051558	396	0.008688021	417	0.0002230795726522782	1.208411	88	92	0.005920743	
GO Biological Process	snRNA metabolic process	418	2.869821e-36	9.034443669617225e-35	2.046187	382	0.008380869	691	0.007376343149782924	1.175199	80	86	0.005382493	
GO Biological Process	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	570	5.930123e-29	1.3690261150350879e-27	2.151664	267	0.005857832	929	0.03265498628740582	1.228246	35	36	0.002354841	
Mouse Phenotype Single KO	pale liver	88	5.625239e-54	5.853444718522728e-52	2.078283	556	0.01219833	417	0.022806463726618705	1.168588	74	80	0.004978806	
Mouse Phenotype Single KO	spontaneous skin ulceration	282	1.643414e-28	5.3364333326241134e-27	2.294517	228	0.005002194	531	0.04975496475329566	1.263338	25	25	0.001682029	
Mouse Phenotype	spontaneous skin ulceration	251	5.019163e-38	1.9118811730278884e-36	2.250987	322	0.007064502	537	0.01770053568435754	1.231755	39	40	0.002623966	
Mouse Phenotype	pancytopenia	385	2.705584e-28	6.718984058181818e-27	2.187188	251	0.005506801	552	0.019589189951086956	1.263338	29	29	0.001951154	
Mouse Phenotype	increased liver adenoma incidence	458	8.741053e-25	1.8247425269213975e-23	2.336375	189	0.004146556	572	0.023891869237762237	1.263338	28	28	0.001883873