# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	66	3.054445e-65	6.089915417424243e-63	2.352746	512	0.01624623	578	0.001885592951262976	1.228979	96	113	0.007395994	
GO Biological Process	regulation of DNA-templated transcription in response to stress	86	4.18683e-59	6.406336740697675e-57	2.189608	539	0.01710297	473	0.0006216080691543341	1.239952	102	119	0.007858243	
GO Biological Process	regulation of intrinsic apoptotic signaling pathway	90	3.408316e-58	4.983336693777778e-56	2.003709	655	0.02078375	844	0.01293316411943128	1.166621	125	155	0.0096302	
GO Biological Process	liver regeneration	97	1.359013e-57	1.84363423371134e-55	3.098436	280	0.008884658	354	0.00008948725908757062	1.44661	35	35	0.002696456	
GO Biological Process	endoplasmic reticulum unfolded protein response	113	3.908647e-53	4.5516713161946903e-51	2.234682	462	0.01465969	745	0.007032310904697987	1.205508	95	114	0.007318952	
GO Biological Process	cellular response to epidermal growth factor stimulus	119	6.174656e-52	6.827924227226891e-50	2.541477	349	0.01107409	1085	0.037347231010138246	1.294335	34	38	0.002619414	
GO Biological Process	response to epidermal growth factor	135	4.168562e-48	4.0632672117037036e-46	2.409035	357	0.01132794	1129	0.04425881043046944	1.274395	37	42	0.002850539	
GO Biological Process	cellular response to topologically incorrect protein	141	1.045181e-46	9.7542814035461e-45	2.012172	517	0.01640489	962	0.022019821935550934	1.165614	112	139	0.008628659	
GO Biological Process	triglyceride homeostasis	145	2.840268e-46	2.577592180137931e-44	3.396369	196	0.006219261	1152	0.046677988604166665	1.31099	29	32	0.002234206	
GO Biological Process	cellular response to unfolded protein	150	9.180152e-46	8.053441344533332e-44	2.059148	478	0.01516738	597	0.0021418022624958124	1.219457	102	121	0.007858243	
GO Biological Process	platelet-derived growth factor receptor signaling pathway	191	2.350976e-41	1.619711685026178e-39	2.310464	332	0.01053467	575	0.001821589613947826	1.402773	32	33	0.002465331	
GO Biological Process	regulation of mitochondrial membrane permeability	202	3.503373e-40	2.2822220449009903e-38	2.15758	374	0.01186736	366	0.00011409474996448088	1.327711	67	73	0.005161787	
GO Biological Process	regulation of membrane permeability	218	3.881633e-39	2.343046268211009e-37	2.059787	406	0.01288275	335	0.00005976751022985074	1.321594	74	81	0.005701079	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to hypoxia	230	1.029135e-37	5.8879945500000005e-36	2.20899	332	0.01053467	778	0.0086022598718509	1.242601	67	78	0.005161787	
GO Biological Process	high-density lipoprotein particle remodeling	331	3.344226e-31	1.3295066445317221e-29	4.048367	104	0.003300016	987	0.024976075311043563	1.44661	17	17	0.001309707	
GO Biological Process	regulation of plasma lipoprotein particle levels	356	1.4312e-29	5.2902137078651685e-28	2.028573	314	0.009963509	662	0.003723917489425982	1.268261	64	73	0.004930663	
GO Biological Process	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	384	2.307885e-28	7.90871320703125e-27	2.078336	283	0.008979851	832	0.012522039553966347	1.252289	58	67	0.004468413	
GO Biological Process	actin filament bundle assembly	410	4.878514e-27	1.5657650177073172e-25	2.005116	294	0.009328891	511	0.0009096149736986302	1.356197	45	48	0.003466872	
GO Biological Process	reverse cholesterol transport	445	1.214867e-25	3.592457270337079e-24	3.448959	103	0.003268285	987	0.024976075311043563	1.44661	17	17	0.001309707	
GO Biological Process	plasma lipoprotein particle clearance	556	1.604992e-21	3.7985772892086333e-20	2.118316	201	0.006377915	934	0.019195289717344754	1.305477	37	41	0.002850539	
GO Cellular Component	high-density lipoprotein particle	63	3.176605e-35	8.712973714285714e-34	3.78742	128	0.004061558	115	0.009128969906086956	1.393032	26	27	0.002003082	
GO Cellular Component	cleavage furrow	83	3.187981e-26	6.637145985542169e-25	2.044345	271	0.00859908	104	0.004446298523076923	1.307513	47	52	0.003620955	
GO Cellular Component	mitochondrial ribosome	109	1.760213e-20	2.7905028110091745e-19	2.054495	205	0.006504839	120	0.011044203839999999	1.225364	72	85	0.005546995	
GO Cellular Component	protein-lipid complex	114	3.28671e-19	4.981960421052631e-18	2.04638	193	0.006124068	101	0.003779305378217822	1.343281	39	42	0.003004622	
GO Cellular Component	plasma lipoprotein particle	116	3.402941e-18	5.069208662068966e-17	2.036564	184	0.00583849	109	0.006374580902752294	1.338114	37	40	0.002850539	
GO Cellular Component	very-low-density lipoprotein particle	134	3.523857e-16	4.544197683582089e-15	2.653537	93	0.002950976	116	0.009206427972413793	1.44661	20	20	0.001540832	
GO Cellular Component	pore complex	233	1.856587e-9	1.3769022901287553e-8	2.06465	84	0.002665397	131	0.0170751066870229	1.44661	18	18	0.001386749	
GO Molecular Function	thyroid hormone receptor binding	155	3.887244e-12	1.0588351076129034e-10	2.054885	114	0.003617325	103	0.01779361080194175	1.394946	27	28	0.002080123	
Human Phenotype	Ectropion	190	3.446588e-12	1.210477985473684e-10	2.017125	120	0.003807711	241	0.023515494173858918	1.390971	25	26	0.00192604	
Human Phenotype	Increased mean platelet volume	331	2.712199e-9	5.4678259598187315e-8	2.146485	75	0.002379819	281	0.04448701496085409	1.44661	17	17	0.001309707	
Mouse Phenotype Single KO	decreased circulating free fatty acid level	54	2.726215e-55	4.622953843518519e-53	2.161865	518	0.01643662	281	0.004296418777935943	1.244396	80	93	0.006163328	
Mouse Phenotype Single KO	pale liver	89	4.256097e-44	4.378997778539326e-42	2.178673	403	0.01278756	497	0.04001087585311871	1.211536	67	80	0.005161787	
Mouse Phenotype Single KO	decreased total retina thickness	474	3.84113e-17	7.420512111814346e-16	2.010286	178	0.005648104	392	0.016979208404081635	1.332404	35	38	0.002696456	
Mouse Phenotype Single KO	increased liver adenoma incidence	800	5.019794e-11	5.74578170725e-10	2.125573	94	0.002982707	377	0.015011264412997348	1.44661	20	20	0.001540832	
Mouse Phenotype	extramedullary hematopoiesis	29	4.199427e-87	1.384507639551724e-84	2.013133	974	0.03090592	495	0.008274413894545455	1.165554	141	175	0.01086287	
Mouse Phenotype	decreased circulating free fatty acid level	70	1.331085e-59	1.8180719549999998e-57	2.026979	652	0.02068856	269	0.00028169318392193315	1.252108	103	119	0.007935285	
Mouse Phenotype	decreased liver cholesterol level	433	2.364144e-20	5.220226509006928e-19	2.12866	187	0.005933682	577	0.013884840459098787	1.356197	30	32	0.002311248	
Mouse Phenotype	increased liver adenoma incidence	471	2.50658e-19	5.08819774522293e-18	2.413634	135	0.004283674	744	0.03678371145967742	1.343281	26	28	0.002003082