# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	RNA processing	1	4.873352e-13	6.4128438968e-9	2.668466	66	0.1617647	11	4.290251499181818e-9	2.527821	66	893	0.1202186	
GO Biological Process	ncRNA metabolic process	3	1.28942e-11	5.655825926666666e-8	3.372964	42	0.1029412	23	0.000011210329460434782	2.588274	42	555	0.07650273	
GO Biological Process	ribonucleoprotein complex biogenesis	4	1.916639e-11	6.305263150250001e-8	3.460867	40	0.09803922	15	5.085453458e-7	3.013408	40	454	0.07285974	
GO Biological Process	ncRNA processing	5	2.923239e-11	7.6933804002e-8	3.910248	34	0.08333333	24	0.000012216234410833332	2.936551	34	396	0.06193078	
GO Biological Process	ribosome biogenesis	9	2.170045e-10	3.172846906111111e-7	4.032884	30	0.07352941	20	0.0000046986808402500005	3.282563	31	323	0.0564663	
GO Biological Process	rRNA processing	11	1.506401e-9	0.0000018020664326363636	4.54397	24	0.05882353	30	0.00018293321597666668	3.257351	24	252	0.04371585	
GO Biological Process	rRNA metabolic process	13	2.769007e-9	0.0000028028740856153845	4.401691	24	0.05882353	33	0.00027384150155151515	3.169315	24	259	0.04371585	
GO Biological Process	translation	16	3.916211e-9	0.0000032208387843125003	3.460473	31	0.07598039	31	0.0002466832408741935	2.758241	30	372	0.05464481	
GO Biological Process	mRNA metabolic process	17	5.011888e-9	0.000003879496128941177	2.539545	48	0.1176471	18	0.000004548324278611112	2.491206	48	659	0.08743169	
GO Biological Process	mitochondrion organization	19	2.164132e-8	0.000014988322625263157	2.740592	39	0.09558824	26	0.000013425297670769232	2.596833	41	540	0.07468124	
GO Biological Process	mitochondrial translation	20	2.734181e-8	0.0000179895438895	6.944676	14	0.03431373	45	0.0008292746239777777	4.475052	14	107	0.02550091	
GO Biological Process	peptide biosynthetic process	21	4.718536e-8	0.0000295672453447619	3.096905	31	0.07598039	40	0.000567927636125	2.617514	30	392	0.05464481	
GO Biological Process	mitochondrial translational elongation	22	6.084488e-8	0.00003639353526909091	7.992149	12	0.02941176	56	0.0015334807752499999	4.828544	12	85	0.02185792	
GO Biological Process	mitochondrial translational termination	23	7.249108e-8	0.000041474353118260865	7.861808	12	0.02941176	58	0.0018929731978448278	4.717543	12	87	0.02185792	
GO Biological Process	cellular component disassembly	24	1.096689e-7	0.0000601305439625	2.91554	32	0.07843137	34	0.00029251733255	2.6707	31	397	0.0564663	
GO Biological Process	macromolecular complex disassembly	25	1.502571e-7	0.000079089327156	4.147369	20	0.04901961	36	0.0003184174977472222	3.581381	20	191	0.03642987	
GO Biological Process	cellular protein complex disassembly	26	4.797683e-7	0.00024281811768076927	5.068212	15	0.03676471	51	0.0010795927421568628	4.071689	15	126	0.0273224	
GO Biological Process	translational termination	27	4.853887e-7	0.0002365640704925926	6.5607	12	0.02941176	67	0.004085887176268657	4.320276	12	95	0.02185792	
GO Biological Process	protein complex disassembly	28	8.11418e-7	0.00038133748078571434	4.292836	17	0.04166667	52	0.0010912090627692307	3.656837	17	159	0.03096539	
GO Biological Process	amide biosynthetic process	29	9.783732e-7	0.00044394527375172415	2.585908	33	0.08088235	55	0.0015443885694181817	2.368983	32	462	0.0582878	
GO Cellular Component	intracellular ribonucleoprotein complex	1	1.506863e-17	2.6038592640000003e-14	3.291688	67	0.1642157	6	1.3547574719999998e-12	2.857185	68	814	0.1238616	
GO Cellular Component	ribonucleoprotein complex	2	1.60486e-17	1.38659904e-14	3.287497	67	0.1642157	7	1.392104448e-12	2.846694	68	817	0.1238616	
GO Cellular Component	ribosomal subunit	6	1.803357e-10	5.19366816e-8	5.889802	21	0.05147059	18	0.000011377296	3.88241	21	185	0.03825137	
GO Cellular Component	ribosome	9	3.462009e-9	6.647057279999999e-7	4.533643	23	0.05637255	20	0.000041754787199999996	3.333264	23	236	0.04189435	
GO Cellular Component	large ribosomal subunit	14	8.253002e-9	0.000001018656246857143	6.974942	15	0.03676471	23	0.000098354304	4.461155	15	115	0.0273224	
GO Cellular Component	preribosome	16	1.674492e-8	0.0000018084513599999999	8.009509	13	0.03186275	19	0.000025492274526315793	5.850374	13	76	0.02367942	
GO Cellular Component	organelle inner membrane	18	3.608396e-8	0.00000346406016	2.778387	37	0.09068627	26	0.0004601981686153846	2.226544	36	553	0.06557377	
GO Cellular Component	mitochondrial ribosome	22	1.158506e-7	0.000009099538036363637	8.515323	11	0.02696078	33	0.001906125381818182	4.426165	11	85	0.02003643	
GO Cellular Component	mitochondrial large ribosomal subunit	23	1.191791e-7	0.000008953977600000001	11.72175	9	0.02205882	29	0.0008868608441379309	6.03568	9	51	0.01639344	
GO Cellular Component	mitochondrial envelope	25	3.978476e-7	0.000027499226112	2.290345	44	0.1078431	27	0.000541849536	2.017287	44	746	0.08014572	
GO Cellular Component	mitochondrial inner membrane	26	4.633018e-7	0.0000307917504	2.728397	32	0.07843137	32	0.00150365484	2.202153	32	497	0.0582878	
GO Cellular Component	mitochondrial membrane	27	7.023168e-7	0.000044948275200000006	2.295564	42	0.1029412	28	0.0006399629485714286	2.040471	42	704	0.07650273	
GO Cellular Component	U4/U6 x U5 tri-snRNP complex	29	0.00001189502	0.0007087791227586207	12.31277	6	0.01470588	43	0.022598108874418602	7.125455	5	24	0.009107468	
GO Cellular Component	spliceosomal tri-snRNP complex	31	0.00001841293	0.0010263723561290323	11.38469	6	0.01470588	51	0.04719520376470588	5.896929	5	29	0.009107468	
GO Cellular Component	spliceosomal complex	34	0.00004367055	0.002219491482352941	3.288254	16	0.03921569	34	0.006044269552941177	2.942124	16	186	0.0291439	
GO Cellular Component	small-subunit processome	35	0.00006195428	0.003058771309714286	9.133391	6	0.01470588	40	0.02070229536	5.863232	6	35	0.01092896	
GO Cellular Component	mitochondrial matrix	36	0.00008297076	0.0039825964799999995	2.321018	26	0.06372549	39	0.018391378707692307	2.034051	27	454	0.04918033	
GO Cellular Component	preribosome, large subunit precursor	39	0.0002010057	0.008906098707692309	9.625672	5	0.0122549	47	0.025227719080851065	6.840437	5	25	0.009107468	
GO Molecular Function	RNA binding	1	3.067965e-14	1.2952948230000002e-10	2.160745	103	0.252451	2	1.1070791184999999e-10	2.150687	103	1638	0.1876138	
GO Molecular Function	structural constituent of ribosome	2	1.676643e-9	0.000003539393373	5.807139	19	0.04656863	5	0.00023935657940000001	4.011367	19	162	0.03460838	
Human Phenotype	Increased serum lactate	1	4.841426e-7	0.0032306835698	5.948668	13	0.03186275	1	0.045924967311	4.446284	13	100	0.02367942