# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	DNA conformation change	22	5.950869e-30	3.559431144136364e-27	2.037517	309	0.03885326	200	0.000535065007475	1.358955	134	281	0.02033693	
GO Biological Process	chromatin assembly or disassembly	30	5.666996e-26	2.4857333454666668e-23	2.293369	204	0.0256507	240	0.002989535091083333	1.408865	88	178	0.01335559	
GO Biological Process	nucleosome organization	31	1.003104e-25	4.2580146890322577e-23	2.332789	195	0.02451905	307	0.008242266096416937	1.383212	83	171	0.01259675	
GO Biological Process	multi-organism metabolic process	33	3.950912e-25	1.575456091151515e-22	2.552727	160	0.02011819	125	0.0000014765829699199999	1.647814	85	147	0.01290029	
GO Biological Process	regulation of gene expression, epigenetic	37	6.279751e-24	2.233384957e-21	2.027694	247	0.03105746	317	0.010132749635015773	1.309966	114	248	0.01730156	
GO Biological Process	viral gene expression	38	6.9974e-24	2.423125963157895e-21	2.763727	132	0.01659751	130	0.0000028927753613846156	1.682923	75	127	0.01138261	
GO Biological Process	chromatin assembly	44	6.29389e-22	1.8823022388636363e-19	2.251648	177	0.02225575	452	0.04315450380752212	1.334693	74	158	0.01123084	
GO Biological Process	cotranslational protein targeting to membrane	48	1.924633e-21	5.276301176458333e-19	2.947617	106	0.0133283	144	0.000010387166308333333	1.744745	60	98	0.009106086	
GO Biological Process	rRNA processing	51	3.712724e-21	9.579555905098038e-19	2.049443	211	0.02653087	257	0.0037906296701945524	1.334407	118	252	0.01790864	
GO Biological Process	response to topologically incorrect protein	53	6.652418e-21	1.6516824238113208e-18	2.150529	186	0.0233874	209	0.0008557071037799043	1.440707	91	180	0.0138109	
GO Biological Process	rRNA metabolic process	55	1.389563e-20	3.324592639454546e-18	2.013498	214	0.02690808	281	0.005312541177580071	1.320347	120	259	0.01821217	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	58	4.714153e-20	1.0695437815e-17	2.939457	99	0.01244813	124	0.0000013371284383870967	1.827557	59	92	0.008954318	
GO Biological Process	mRNA catabolic process	61	6.451816e-20	1.3917942089180328e-17	2.05247	197	0.02477053	112	5.773943617142858e-7	1.551976	116	213	0.0176051	
GO Biological Process	viral transcription	62	6.589555e-20	1.3985799071774196e-17	2.643622	117	0.01471143	137	0.0000042590947681021895	1.714894	68	113	0.01032023	
GO Biological Process	cellular response to topologically incorrect protein	63	7.979158e-20	1.6666307955873017e-17	2.313407	150	0.01886081	364	0.01911073978269231	1.394122	68	139	0.01032023	
GO Biological Process	DNA packaging	64	9.772379e-20	2.009292738453125e-17	2.019515	203	0.02552496	349	0.01658078491747851	1.331793	93	199	0.01411443	
GO Biological Process	gene silencing	66	4.686606e-19	9.344098235454545e-17	2.140913	170	0.02137558	324	0.011805324734876542	1.361547	86	180	0.01305206	
GO Biological Process	nuclear-transcribed mRNA catabolic process	70	9.37527e-19	1.7624168275714284e-16	2.073886	180	0.02263297	148	0.000014001078196621621	1.511231	105	198	0.01593565	
GO Biological Process	regulation of gene silencing	77	1.576051e-18	2.6934097544155846e-16	2.277277	144	0.01810637	399	0.026149472456140348	1.392244	64	131	0.009713158	
GO Biological Process	protein targeting to ER	78	1.640414e-18	2.767462541794872e-16	2.71854	103	0.01295109	152	0.000015561772799342106	1.721136	61	101	0.009257854	
GO Cellular Component	ribosomal subunit	27	1.659079e-23	1.06181056e-21	2.402852	167	0.02099837	47	0.0001402305089361702	1.463385	95	185	0.01441797	
GO Cellular Component	ribosome	31	3.929578e-21	2.190422833548387e-19	2.073016	205	0.02577644	45	0.000061336128	1.424875	118	236	0.01790864	
GO Cellular Component	DNA packaging complex	33	1.382865e-18	7.241183999999999e-17	2.826132	97	0.01219666	104	0.04673469046153847	1.373986	54	112	0.008195477	
GO Cellular Component	ficolin-1-rich granule lumen	35	8.144166e-18	4.0208910994285714e-16	2.326141	132	0.01659751	101	0.04646165988118812	1.355929	59	124	0.008954318	
GO Cellular Component	Golgi-associated vesicle membrane	44	2.798946e-15	1.099222429090909e-13	2.851233	77	0.009681881	62	0.007767343277419355	1.70985	30	50	0.004553043	
GO Cellular Component	cytosolic ribosome	56	5.579447e-13	1.7216579314285715e-11	2.116076	114	0.01433421	52	0.0006728187323076923	1.552096	61	112	0.009257854	
GO Cellular Component	large ribosomal subunit	58	1.201835e-12	3.5806394482758615e-11	2.26622	95	0.01194518	61	0.007144280026229508	1.462045	59	115	0.008954318	
GO Cellular Component	vesicle coat	76	1.979835e-10	4.501519578947369e-9	2.280249	75	0.009430404	107	0.04716500097196262	1.564568	28	51	0.004249507	
GO Cellular Component	cytoplasmic stress granule	94	1.815378e-8	3.3372055148936173e-7	2.288326	58	0.007292845	69	0.014894135373913044	1.723104	26	43	0.003945971	
GO Cellular Component	cytosolic large ribosomal subunit	100	3.694045e-8	6.38330976e-7	2.222328	59	0.007418584	72	0.0182708784	1.588385	34	61	0.005160115	
GO Cellular Component	COPI-coated vesicle	103	5.197305e-8	8.719362174757282e-7	3.090388	32	0.004023639	58	0.004998713710344827	2.106337	17	23	0.002580058	
GO Cellular Component	COPI-coated vesicle membrane	119	6.582656e-7	0.000009558680309243697	3.138801	26	0.003269207	86	0.026743412093023257	2.137312	12	16	0.001821217	
GO Cellular Component	mitochondrial nucleoid	121	7.802381e-7	0.00001114257385785124	2.379063	41	0.005155287	80	0.0225604872	1.69628	25	42	0.003794202	
GO Cellular Component	spliceosomal snRNP complex	125	0.000001509486	0.000020867134464000002	2.152716	48	0.006035458	98	0.04500001175510204	1.516802	33	62	0.005008347	
GO Cellular Component	small nuclear ribonucleoprotein complex	131	0.000002329804	0.000030732071083969463	2.017082	54	0.006789891	68	0.013367370917647059	1.569427	38	69	0.005767188	
GO Cellular Component	COPI vesicle coat	199	0.0002586783	0.0022462115698492465	2.493815	20	0.002514774	99	0.04474062545454545	2.192115	10	13	0.001517681	
GO Cellular Component	spliceosomal tri-snRNP complex	208	0.0004216837	0.0035032184307692304	2.238859	23	0.00289199	102	0.04641582494117648	1.76881	18	29	0.002731826	
GO Molecular Function	structural constituent of ribosome	14	1.375472e-18	4.14803056e-16	2.273557	145	0.01823211	49	0.0007198577207346938	1.477648	84	162	0.01274852	
GO Molecular Function	nucleosome binding	20	2.182321e-15	4.606879631e-13	2.5801	92	0.01156796	65	0.010019299649230769	1.640765	38	66	0.005767188	
GO Molecular Function	ribonucleoprotein complex binding	21	3.720753e-15	7.480485317142857e-13	2.271223	116	0.01458569	89	0.02375925281797753	1.437265	58	115	0.00880255	
Mouse Phenotype Single KO	increased integument system tumor incidence	49	3.299392e-10	6.165822968163266e-8	2.141027	84	0.01056205	59	0.006187471813898305	1.649855	44	76	0.006677796	
Mouse Phenotype Single KO	increased myocardial infarction size	69	1.585044e-8	0.0000021035141895652174	2.656589	44	0.005532503	154	0.047138779204545456	1.982434	16	23	0.00242829	
Mouse Phenotype Single KO	increased hemoglobin concentration distribution width	99	4.457228e-7	0.000041227107874747475	3.930147	20	0.002514774	147	0.040727725943537414	2.84975	7	7	0.001062377	
Mouse Phenotype Single KO	embryo cyst	293	0.0003386883	0.010584876324573379	2.379851	21	0.002640513	136	0.037047834983823524	2.564775	9	10	0.001365913	
Mouse Phenotype Single KO	fused dorsal root ganglion	303	0.0004000799	0.012090863512541255	2.126465	26	0.003269207	133	0.033722828148120304	2.2798	12	15	0.001821217	
Mouse Phenotype	abnormal platelet aggregation	2	1.175539e-41	5.6196641895e-38	3.178996	191	0.02401609	154	0.006637171698701298	1.546141	51	94	0.007740173	
Mouse Phenotype	abnormal platelet activation	3	1.363742e-41	4.346245754e-38	3.15246	193	0.02426757	168	0.010077527333928572	1.510367	53	100	0.008043709	
Mouse Phenotype	abnormal platelet physiology	4	1.39124e-28	3.32541141e-25	2.359576	213	0.02678235	143	0.0050486887244055945	1.468053	68	132	0.01032023	
Mouse Phenotype	increased myocardial infarction size	72	9.615007e-10	1.2767928045416668e-7	2.739962	49	0.006161197	306	0.04948664242156863	1.863298	17	26	0.002580058	
Mouse Phenotype	increased cellular sensitivity to ultraviolet irradiation	88	2.084839e-8	0.0000022651301907954543	2.825411	39	0.00490381	300	0.047397382700000004	1.804841	19	30	0.002883594	
Mouse Phenotype	absent tongue	91	2.530187e-8	0.0000026583646051648352	2.84949	38	0.004778071	176	0.011376068931818183	2.315422	13	16	0.001972985	
Mouse Phenotype	pancytopenia	112	7.711827e-8	0.000006583283745267857	2.397159	48	0.006035458	174	0.01147392531724138	1.965345	20	29	0.003035362	
Mouse Phenotype	increased hemoglobin concentration distribution width	138	4.457228e-7	0.00003088083833913043	3.930147	20	0.002514774	243	0.02572475971234568	2.84975	7	7	0.001062377	
Mouse Phenotype	embryo cyst	333	0.0003386883	0.00972432082972973	2.379851	21	0.002640513	228	0.02307368710263158	2.564775	9	10	0.001365913