# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	155	2.608164e-28	2.2142471016774193e-26	2.281596	228	0.01240951	406	0.0014701212112068964	1.29935	90	118	0.008165487	
GO Biological Process	regulation of mitochondrial membrane permeability	209	3.435669e-24	2.16315638138756e-22	2.157193	218	0.01186524	557	0.009062310352782765	1.330203	57	73	0.005171475	
GO Biological Process	cotranslational protein targeting to membrane	250	3.892636e-21	2.0489278849600002e-19	2.190723	182	0.00990584	371	0.0009041431852291105	1.338537	77	98	0.006986028	
GO Biological Process	apoptotic mitochondrial changes	254	4.818917e-21	2.4965405040551177e-19	2.14017	191	0.01039569	502	0.004839777968725099	1.385974	48	59	0.004354927	
GO Biological Process	protein targeting to ER	257	6.744585e-21	3.4533849811284046e-19	2.147867	188	0.01023241	334	0.00040148148398203595	1.34938	80	101	0.007258211	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	272	1.937188e-20	9.371859151470588e-19	2.210606	172	0.009361563	488	0.004006656634426229	1.314729	71	92	0.006441662	
GO Biological Process	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	302	2.83151e-19	1.2337695394039736e-17	2.154084	171	0.009307135	636	0.0184015890495283	1.322191	52	67	0.004717837	
GO Biological Process	platelet-derived growth factor receptor signaling pathway	371	1.577864e-16	5.59652624690027e-15	2.017368	169	0.00919828	535	0.006891761840186916	1.497097	29	33	0.002631101	
GO Biological Process	triglyceride homeostasis	387	6.304852e-16	2.1438125960723513e-14	2.675091	90	0.004898492	725	0.03238371818896552	1.437406	27	32	0.002449646	
GO Biological Process	protein-lipid complex subunit organization	443	1.709055e-14	5.076626353273138e-13	2.14367	126	0.006857889	657	0.022066040686453577	1.377373	38	47	0.00344765	
GO Biological Process	negative regulation of pri-miRNA transcription from RNA polymerase II promoter	471	5.810292e-14	1.6233042978343951e-12	2.480823	89	0.004844065	791	0.04732898029077118	1.703593	11	11	0.000998004	
GO Biological Process	regulation of cholesterol homeostasis	514	2.687173e-13	6.879476557782101e-12	3.301256	53	0.002884668	712	0.030851663616573034	1.703593	12	12	0.001088732	
GO Biological Process	release of cytochrome c from mitochondria	619	7.75789e-12	1.6492096043618738e-10	2.474994	74	0.004027649	710	0.030581960811267607	1.541346	19	21	0.001723825	
GO Biological Process	cholesterol efflux	653	2.565233e-11	5.169356975038285e-10	2.538258	67	0.003646655	762	0.04135460970209974	1.490644	21	24	0.00190528	
GO Biological Process	reverse cholesterol transport	673	4.913577e-11	9.607393721099554e-10	2.929262	51	0.002775812	692	0.028635619367052022	1.603381	16	17	0.001451642	
GO Biological Process	high-density lipoprotein particle remodeling	756	2.952343e-10	5.138873219179894e-9	3.004666	45	0.002449246	692	0.028635619367052022	1.603381	16	17	0.001451642	
GO Biological Process	plasma lipoprotein particle remodeling	906	4.717753e-9	6.852197762362032e-8	2.093165	77	0.004190932	746	0.03710936780697051	1.460222	24	28	0.002177463	
GO Biological Process	pyrimidine-containing compound transmembrane transport	1435	0.000002994194	0.000027456863307317075	2.099166	48	0.002612529	765	0.041754091844444445	1.597118	15	16	0.001360915	
GO Biological Process	receptor recycling	2570	0.0008745537	0.00447791911996109	2.119064	23	0.001251837	791	0.04732898029077118	1.703593	11	11	0.000998004	
GO Cellular Component	ESCRT complex	186	8.652114e-7	0.000008038093006451612	2.123784	52	0.00283024	78	0.009857827938461537	1.521065	25	28	0.002268191	
Mouse Phenotype	dry eyes	141	7.223864e-21	4.89839458893617e-19	2.935207	104	0.00566048	563	0.04122232792007105	1.597118	15	16	0.001360915	
Mouse Phenotype	increased follicular B cell number	275	1.078657e-14	3.7501962098181814e-13	2.129097	130	0.0070756	518	0.032931793963320466	1.437406	27	32	0.002449646	
Mouse Phenotype	fusion of vertebral bodies	1710	0.00105902	0.005921222350877193	2.017176	25	0.001360692	596	0.045639176828859054	1.703593	11	11	0.000998004