# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	negative regulation of gene expression, epigenetic	1	1.042948e-24	1.3724152732000002e-20	7.534068	45	0.04079782	81	0.00007213460005802468	3.137343	24	114	0.01904762	
GO Biological Process	regulation of gene expression, epigenetic	2	9.551601e-21	6.28447587795e-17	3.965845	67	0.06074343	75	0.000012590011858133334	2.4637	41	248	0.03253968	
GO Biological Process	protein folding	3	6.317891e-18	2.7712375889666664e-14	3.812323	60	0.0543971	106	0.0024955857287735847	2.176011	33	226	0.02619048	
GO Biological Process	protein peptidyl-prolyl isomerization	4	3.356838e-16	1.10431578105e-12	7.738557	28	0.02538531	164	0.029141696734146343	3.548186	10	42	0.007936508	
GO Biological Process	peptidyl-proline modification	7	1.908616e-15	3.5879254205714287e-12	6.333492	31	0.02810517	128	0.008224175558906251	3.398789	13	57	0.01031746	
GO Biological Process	DNA conformation change	9	1.681139e-13	2.458012011222222e-10	2.947745	62	0.05621034	121	0.007097528504214876	1.962235	37	281	0.02936508	
GO Biological Process	chromosome organization	12	4.410658e-13	4.836654051833334e-10	2.214316	99	0.08975521	96	0.0011158054796562501	1.727439	67	578	0.0531746	
GO Biological Process	chromatin silencing	13	9.252693e-13	9.365860552846153e-10	6.348984	25	0.02266546	107	0.0025161606757009344	2.919023	19	97	0.01507937	
GO Biological Process	protein-DNA complex assembly	21	6.238688e-11	3.9092807329523814e-8	2.905226	50	0.04533092	141	0.014301761157446807	2.041422	30	219	0.02380952	
GO Biological Process	protein-DNA complex subunit organization	29	1.551661e-9	7.04079555137931e-7	2.60524	51	0.04623753	191	0.04828421535706806	1.847895	31	250	0.02460317	
GO Biological Process	gene silencing	31	5.168319e-9	0.000002193868055516129	3.178145	35	0.03173164	123	0.00739838457	2.235357	27	180	0.02142857	
GO Biological Process	regulation of mRNA stability	69	7.195438e-7	0.00013722430237971014	2.664775	33	0.0299184	109	0.002888126454770642	2.467282	25	151	0.01984127	
GO Biological Process	regulation of gene silencing	80	0.000001634797	0.0002689036715375	2.964709	26	0.02357208	144	0.015253656930555557	2.388931	21	131	0.01666667	
GO Biological Process	regulation of RNA stability	85	0.000002613802	0.00040464730021176463	2.50622	33	0.0299184	120	0.007066872076166667	2.328497	25	160	0.01984127	
GO Biological Process	positive regulation of supramolecular fiber organization	87	0.000003360926	0.0005083497153333333	2.302001	38	0.0344515	183	0.04440480820655738	2.089968	23	164	0.01825397	
GO Biological Process	RNA splicing, via transesterification reactions	100	0.000006489213	0.0008539155386700001	2.071439	45	0.04079782	175	0.036066081928	1.811053	35	288	0.02777778	
GO Biological Process	regulation of gene silencing by miRNA	109	0.00001622155	0.0019583429032110095	2.959162	21	0.01903898	187	0.04721116354705883	2.390004	17	106	0.01349206	
GO Biological Process	chromatin remodeling	113	0.00001837832	0.0021401797600000003	2.182611	36	0.03263826	101	0.0014827013994059405	2.468493	27	163	0.02142857	
GO Biological Process	heterochromatin assembly	123	0.00002815583	0.0030122159916260165	8.315939	7	0.006346328	152	0.02214260601381579	7.45119	5	10	0.003968254	
GO Biological Process	tricuspid valve development	126	0.00003675508	0.003838572204126984	6.65493	8	0.007252947	154	0.023180133912337662	9.934921	4	6	0.003174603	
GO Cellular Component	nucleosome	1	3.321022e-18	5.7387260159999995e-15	8.021035	31	0.02810517	28	0.003976582217142857	2.696621	19	105	0.01507937	
GO Cellular Component	DNA packaging complex	2	1.847133e-17	1.595922912e-14	6.932504	33	0.0299184	26	0.003378072516923077	2.661139	20	112	0.01587302	
GO Cellular Component	cytoplasmic stress granule	20	0.0000186071	0.00160765344	3.982662	14	0.01269266	31	0.024811822451612904	3.46567	10	43	0.007936508	
GO Cellular Component	histone acetyltransferase complex	40	0.0006674133	0.028832254560000003	2.501637	17	0.01541251	32	0.0383677668	2.640928	14	79	0.01111111	
GO Cellular Component	transcriptional repressor complex	41	0.0007316574	0.030836682614634143	2.181322	22	0.0199456	22	0.0023688225163636363	3.052295	17	83	0.01349206	
GO Molecular Function	peptidyl-prolyl cis-trans isomerase activity	1	3.356838e-16	1.4172570036000001e-12	7.738557	28	0.02538531	40	0.03833487338	3.548186	10	42	0.007936508	
GO Molecular Function	isomerase activity	5	8.782669e-13	7.4160857036e-10	3.692802	43	0.03898459	35	0.02003517530285714	2.285032	23	150	0.01825397	
GO Molecular Function	mRNA 3'-UTR binding	9	0.000001057041	0.000495869678	3.21184	24	0.02175884	28	0.0036366197	3.386905	15	66	0.01190476	
GO Molecular Function	BMP receptor activity	10	0.000002834972	0.0011969251784	9.537816	8	0.007252947	24	0.00134606067875	12.41865	5	6	0.003968254	
GO Molecular Function	mRNA binding	16	0.00001333824	0.00351962808	2.069404	42	0.03807797	20	0.00037667839599999996	2.470861	32	193	0.02539683	
Mouse Phenotype Single KO	abnormal cellular replicative senescence	5	2.687372e-12	4.9216530808e-9	6.037799	25	0.02266546	128	0.039087799125	2.980476	12	60	0.00952381	
Mouse Phenotype Single KO	vertebral transformation	74	0.0002414174	0.02987377205135135	2.496697	20	0.01813237	80	0.013468458987499998	2.753701	17	92	0.01349206	
Mouse Phenotype Single KO	decreased pancreatic beta cell proliferation	77	0.0002690551	0.03199659156753246	4.963244	8	0.007252947	67	0.008705786774925374	9.313988	5	8	0.003968254	
Mouse Phenotype	increased thyroid tumor incidence	4	1.632963e-12	3.90318981075e-9	8.286828	20	0.01813237	235	0.0403057014919149	4.172667	7	25	0.005555556	
Mouse Phenotype	early cellular replicative senescence	8	4.641971e-11	5.547735591375e-8	4.859019	27	0.02447869	163	0.018036439367484666	2.857991	14	73	0.01111111	
Mouse Phenotype	abnormal cellular replicative senescence	10	1.399302e-10	1.3378726421999998e-7	4.458405	28	0.02538531	180	0.02268963403333333	2.661139	15	84	0.01190476	
Mouse Phenotype	pulmonary alveolar hemorrhage	51	0.00005300176	0.009936271124705884	4.114591	12	0.01087942	156	0.016335366875	5.960952	6	15	0.004761905	
Mouse Phenotype	increased lung adenoma incidence	60	0.0001170497	0.018651869695	3.179695	15	0.01359927	120	0.005238548387999999	3.459481	13	56	0.01031746	
Mouse Phenotype	abnormal lung adenoma incidence	62	0.0001234248	0.019033298593548388	3.163984	15	0.01359927	126	0.006070328981428572	3.398789	13	57	0.01031746