# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	ncRNA processing	29	2.516099e-38	1.1417016117586208e-35	2.060395	389	0.04391015	82	4.664900804634146e-11	1.477324	218	396	0.03115621	
GO Biological Process	translation	31	6.454107e-38	2.739664323e-35	2.035844	396	0.0447003	46	3.27624772173913e-17	1.615918	224	372	0.03201372	
GO Biological Process	mRNA catabolic process	44	1.496217e-31	4.474708977954545e-29	2.310223	247	0.02788125	150	1.7689196294e-7	1.537073	122	213	0.01743604	
GO Biological Process	translational initiation	57	1.993813e-28	4.6029096959649116e-26	2.622297	174	0.01964104	139	3.610207624244605e-8	1.688966	90	143	0.01286266	
GO Biological Process	translational elongation	62	6.216069e-28	1.3193105156612904e-25	2.944892	141	0.01591602	127	1.6711080363779527e-8	1.797039	75	112	0.01071888	
GO Biological Process	RNA catabolic process	63	2.54802e-27	5.322126219047619e-25	2.099083	262	0.02957444	161	8.045766503540373e-7	1.480979	133	241	0.01900815	
GO Biological Process	nuclear-transcribed mRNA catabolic process	66	4.611899e-27	9.195148324393938e-25	2.265181	219	0.02472062	163	8.351831620858895e-7	1.531537	113	198	0.01614978	
GO Biological Process	rRNA processing	68	1.2074e-26	2.3364965588235296e-24	2.136317	245	0.02765549	151	1.965240876754967e-7	1.490877	140	252	0.02000858	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	72	2.883867e-26	5.270667479583334e-24	2.864035	138	0.01557738	156	4.865977196282051e-7	1.705664	75	118	0.01071888	
GO Biological Process	rRNA metabolic process	75	8.138243e-26	1.4278818618266665e-23	2.094766	248	0.02799413	152	2.309742132236842e-7	1.481667	143	259	0.02043733	
GO Biological Process	response to topologically incorrect protein	82	4.775951e-24	7.66423648890244e-22	2.179706	210	0.02370471	301	0.013596779382724253	1.341789	90	180	0.01286266	
GO Biological Process	RNA 3'-end processing	87	2.417072e-23	3.655890856091954e-21	2.77576	128	0.01444858	298	0.01140709552281879	1.45465	58	107	0.008289267	
GO Biological Process	cellular response to topologically incorrect protein	95	1.345016e-22	1.863059530947368e-20	2.339881	169	0.01907665	331	0.023592146941993956	1.370749	71	139	0.01014721	
GO Biological Process	mitochondrial translational termination	105	1.769542e-21	2.2176574455238097e-19	3.04746	101	0.01140084	171	0.0000018586302577192985	1.789052	58	87	0.008289267	
GO Biological Process	mitochondrial translational elongation	106	1.788977e-21	2.220863051226415e-19	3.067311	100	0.01128796	170	0.0000017876904010588235	1.799576	57	85	0.008146348	
GO Biological Process	cotranslational protein targeting to membrane	112	7.4258e-21	8.724651982142856e-19	2.795951	112	0.01264251	147	1.243964133333333e-7	1.807308	66	98	0.009432614	
GO Biological Process	mRNA 3'-end processing	115	1.765935e-20	2.020690318695652e-18	2.94613	101	0.01140084	263	0.0025153453517110266	1.603177	46	77	0.006574246	
GO Biological Process	macromolecular complex disassembly	116	2.54481e-20	2.8868236887931035e-18	2.015119	211	0.02381759	205	0.00023975627390731706	1.433115	102	191	0.01457768	
GO Biological Process	viral gene expression	119	5.452104e-20	6.02892744e-18	2.481084	132	0.0149001	102	3.76738944754902e-10	1.817227	86	127	0.01229098	
GO Biological Process	mitochondrial translation	127	2.196118e-19	2.2754895088188973e-17	2.627225	115	0.01298115	172	0.0000022563568987209303	1.705452	68	107	0.009718451	
GO Cellular Component	ribosomal subunit	27	4.495099e-35	2.87686336e-33	2.686706	208	0.02347895	28	1.174098857142857e-13	1.769711	122	185	0.01743604	
GO Cellular Component	ribosome	29	1.516571e-31	9.036671337931034e-30	2.287681	252	0.02844565	31	8.798970425806451e-11	1.603325	141	236	0.02015149	
GO Cellular Component	large ribosomal subunit	39	6.809069e-23	3.016941341538462e-21	2.741163	128	0.01444858	33	4.869905105454546e-9	1.796831	77	115	0.01100472	
GO Cellular Component	mitochondrial ribosome	42	9.709392e-22	3.99472128e-20	3.279984	92	0.01038492	43	0.0000031534392558139533	1.768005	56	85	0.00800343	
GO Cellular Component	methyltransferase complex	49	3.844059e-16	1.355619173877551e-14	2.321329	119	0.01343267	133	0.04574177106766917	1.386024	47	91	0.006717164	
GO Cellular Component	small ribosomal subunit	52	5.526564e-15	1.8365197292307692e-13	2.672085	84	0.009481883	52	0.000042622748307692306	1.751781	47	72	0.006717164	
GO Cellular Component	catalytic step 2 spliceosome	55	2.4557e-14	7.715362909090909e-13	2.252748	111	0.01252963	67	0.0005529489098507462	1.565421	56	96	0.00800343	
GO Cellular Component	mitochondrial large ribosomal subunit	59	3.196503e-13	9.361961328813559e-12	3.23906	54	0.006095496	65	0.0005093388996923077	1.789052	34	51	0.004859225	
GO Cellular Component	cytosolic ribosome	65	1.201305e-12	3.193623138461539e-11	2.032977	122	0.01377131	42	0.000002058035245714286	1.677237	70	112	0.01000429	
GO Cellular Component	cytosolic large ribosomal subunit	69	2.839105e-11	7.110106434782608e-10	2.434641	72	0.008127328	53	0.00006381611592452829	1.803717	41	61	0.005859654	
GO Cellular Component	mitochondrial small ribosomal subunit	72	5.808528e-11	1.3940467199999998e-9	3.659088	37	0.004176544	90	0.00482340864	1.916842	20	28	0.002858368	
GO Cellular Component	preribosome	79	7.433774e-10	1.626020439493671e-8	2.184886	77	0.008691726	87	0.0039949492965517235	1.553651	44	76	0.006288409	
GO Cellular Component	mediator complex	93	2.437367e-8	4.528785135483871e-7	2.216226	61	0.006885653	93	0.006037897703225806	1.789052	24	36	0.003430041	
GO Cellular Component	cytoplasmic dynein complex	98	4.667974e-8	8.230876604081632e-7	2.389212	50	0.005643978	105	0.012839446491428572	1.951694	16	22	0.002286694	
GO Cellular Component	INO80-type complex	107	1.785156e-7	0.0000028829435214953273	3.470102	25	0.002821989	119	0.024350496806722688	1.866837	16	23	0.002286694	
GO Cellular Component	cytosolic small ribosomal subunit	148	0.000005372724	0.00006273018291891892	2.10649	45	0.00507958	106	0.01619730040754717	1.646741	27	44	0.003858797	
GO Cellular Component	spliceosomal snRNP complex	150	0.000005664169	0.00006525122687999999	2.013084	50	0.005643978	134	0.04617963940298508	1.47164	34	62	0.004859225	
GO Cellular Component	NuA4 histone acetyltransferase complex	178	0.00004314035	0.00041880070112359553	2.367531	28	0.003160628	101	0.009450322502970298	2.087228	14	18	0.002000858	
GO Cellular Component	intraciliary transport particle	196	0.0001057075	0.0009319518367346939	2.206602	29	0.003273507	78	0.0016199824984615386	1.928822	23	32	0.003287123	
GO Cellular Component	Swr1 complex	207	0.0001611388	0.0013451586782608695	3.934363	11	0.001241675	126	0.030622422857142857	2.385403	8	9	0.001143347	
GO Molecular Function	structural constituent of ribosome	11	1.833382e-26	7.036853458181819e-24	2.491479	177	0.01997968	8	1.49379268075e-10	1.755922	106	162	0.01514935	
GO Molecular Function	ribonucleoprotein complex binding	29	3.526812e-12	5.134551815172414e-10	2.038947	116	0.01309403	33	0.00007568097483030304	1.610147	69	115	0.009861369	
Mouse Phenotype Single KO	decreased circulating total protein level	97	4.73724e-9	4.472052235051547e-7	2.017588	84	0.009481883	177	0.03926566608983051	1.573132	34	58	0.004859225	
Mouse Phenotype	absent fibroblast proliferation	87	6.112549e-10	6.717480573448277e-8	3.351861	37	0.004176544	222	0.039543361433783786	2.415221	9	10	0.001286266	
Mouse Phenotype	decreased circulating total protein level	117	3.599829e-9	2.941706416153846e-7	2.020749	85	0.009594762	183	0.02445836504590164	1.591953	35	59	0.005002144