# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	endoplasmic reticulum unfolded protein response	22	1.29371e-78	7.73814995e-76	2.346576	624	0.01539372	351	0.000001040098981908832	1.234375	110	114	0.007494209	
GO Biological Process	cellular response to topologically incorrect protein	27	1.065429e-73	5.1925852633333334e-71	2.145345	709	0.01749063	286	4.4265468079020984e-8	1.233245	134	139	0.009129309	
GO Biological Process	cellular response to unfolded protein	38	3.260616e-68	1.1291169985263159e-65	2.160209	645	0.01591178	317	2.5672519916719244e-7	1.236972	117	121	0.007971113	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	39	1.40579e-67	4.743279643589744e-65	2.197134	615	0.0151717	396	0.00000725960430631313	1.222657	108	113	0.007357951	
GO Biological Process	IRE1-mediated unfolded protein response	50	1.427462e-61	3.7567944916000004e-59	2.880249	336	0.008288928	524	0.0002646048886641221	1.257205	57	58	0.003883363	
GO Biological Process	regulation of DNA-templated transcription in response to stress	56	2.821136e-58	6.629165825714285e-56	2.024473	641	0.0158131	368	0.0000022785405661141303	1.225511	114	119	0.007766726	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	58	1.268576e-57	2.8781364800000004e-55	2.249701	496	0.01223604	329	4.714725710942249e-7	1.235897	114	118	0.007766726	
GO Biological Process	negative regulation of intrinsic apoptotic signaling pathway	66	1.242326e-52	2.47693452030303e-50	2.067631	548	0.01351885	794	0.008525261998488664	1.170388	86	94	0.005859109	
GO Biological Process	liver regeneration	80	3.720601e-48	6.119923569875001e-46	2.623982	305	0.007524176	692	0.003401668055635838	1.279261	35	35	0.002384521	
GO Biological Process	viral gene expression	97	1.350982e-44	1.832739395670103e-42	2.016939	491	0.01211269	295	7.538108616271187e-8	1.23897	123	127	0.008379888	
GO Biological Process	mitochondrial transmembrane transport	99	2.907589e-44	3.8647438031313134e-42	2.172231	408	0.01006513	484	0.00007966132343801652	1.233023	80	83	0.005450334	
GO Biological Process	cotranslational protein targeting to membrane	106	1.593089e-43	1.977684731226415e-41	2.176848	399	0.009843102	331	4.931710937462236e-7	1.253154	96	98	0.006540401	
GO Biological Process	protein targeting to ER	124	5.812917e-41	6.168723774435484e-39	2.102397	406	0.01001579	318	2.5890109045283017e-7	1.25393	99	101	0.006744788	
GO Biological Process	positive regulation of mRNA metabolic process	139	1.374624e-38	1.3013436846043167e-36	2.165763	356	0.008782317	929	0.023062755192680303	1.205458	49	52	0.003338329	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	141	2.792698e-38	2.6063200696453903e-36	2.132078	366	0.009029011	361	0.0000017674155447645428	1.251451	90	92	0.006131626	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to hypoxia	148	2.417634e-37	2.1495706625675678e-35	2.043286	395	0.009744425	513	0.00021620750021442497	1.230059	75	78	0.005109688	
GO Biological Process	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	166	1.275786e-35	1.0113293960240964e-33	2.072585	363	0.008955003	454	0.00003785551555726872	1.260168	66	67	0.004496525	
GO Biological Process	response to epidermal growth factor	167	1.887359e-35	1.4871710826946108e-33	2.019817	385	0.00949773	976	0.03439006227151639	1.218344	40	42	0.002725167	
GO Biological Process	regulation of mitophagy	186	4.13079e-33	2.9224228822580646e-31	2.290853	268	0.006611407	668	0.0025800425799401196	1.252043	46	47	0.003133942	
GO Biological Process	mitochondrial translational termination	196	2.885525e-32	1.9372767079081634e-30	2.096948	318	0.007844879	330	4.7478668893939393e-7	1.264557	86	87	0.005859109	
GO Cellular Component	mitochondrial ribosome	42	5.509886e-38	2.2669245257142855e-36	2.329694	299	0.007376159	107	0.000003800033495327103	1.249161	83	85	0.005654721	
GO Cellular Component	PcG protein complex	48	5.11538e-36	1.8415367999999998e-34	2.107061	353	0.008708309	168	0.001690326514285714	1.251451	45	46	0.003065813	
GO Cellular Component	cleavage furrow	50	1.454626e-35	5.027187456e-34	2.087908	356	0.008782317	117	0.00003970914461538461	1.279261	52	52	0.003542717	
GO Cellular Component	mitochondrial large ribosomal subunit	60	7.812005e-29	2.24985744e-27	2.516925	192	0.00473653	154	0.0005905841703896104	1.254178	50	51	0.003406459	
GO Cellular Component	nuclear ubiquitin ligase complex	67	6.065072e-27	1.5642454352238809e-25	2.456695	187	0.004613183	153	0.0005880757835294118	1.279261	40	40	0.002725167	
GO Cellular Component	cytoplasmic stress granule	75	6.504624e-25	1.4986653696e-23	2.028062	262	0.006463391	181	0.003091286983425414	1.249511	42	43	0.002861425	
GO Cellular Component	ESCRT complex	123	2.605635e-16	3.6605994146341465e-15	2.295451	124	0.003059009	197	0.00882616787817259	1.279261	28	28	0.001907617	
GO Cellular Component	COPI-coated vesicle	175	4.046014e-12	3.995149824e-11	2.084231	110	0.002713637	222	0.026883803675675676	1.279261	23	23	0.001566971	
GO Molecular Function	unfolded protein binding	9	3.311516e-53	1.553468950222222e-50	2.272818	447	0.01102724	96	0.0001961038078333333	1.20685	100	106	0.006812917	
GO Molecular Function	rRNA binding	12	3.915197e-39	1.3774968111666665e-36	2.775766	223	0.005501283	118	0.0020908921883050846	1.236619	58	60	0.003951492	
GO Molecular Function	cyclin-dependent protein serine/threonine kinase regulator activity	23	4.254702e-27	7.810152975652174e-25	2.375567	201	0.004958555	169	0.019642003105325444	1.279261	29	29	0.001975746	
GO Molecular Function	5'-3' RNA polymerase activity	70	3.220377e-15	1.9423473848571427e-13	2.005084	157	0.0038731	185	0.03155114292972973	1.222405	43	45	0.002929554	
GO Molecular Function	DNA-directed 5'-3' RNA polymerase activity	76	8.645726e-15	4.802928312105262e-13	2.005216	152	0.003749753	196	0.04483934172448979	1.219761	41	43	0.002793296	
Human Phenotype	Aplasia/hypoplasia of the femur	21	3.253298e-38	1.0337741692380954e-35	2.56309	250	0.006167357	334	0.005854666434730539	1.279261	33	33	0.002248263	
Human Phenotype	Aplasia/Hypoplasia involving the femoral head and neck	24	6.812524e-38	1.8941655271666665e-35	3.035548	187	0.004613183	456	0.02411639760526316	1.279261	26	26	0.001771358	
Human Phenotype	Short femoral neck	26	7.920082e-36	2.0327195071538464e-33	3.01649	178	0.004391158	519	0.044407233537572255	1.279261	23	23	0.001566971	
Human Phenotype	Abnormality of transition element cation homeostasis	53	2.50045e-22	3.1482080849056604e-20	2.771998	123	0.00303434	401	0.013083712825935163	1.279261	29	29	0.001975746	
Human Phenotype	Abnormality of iron homeostasis	87	5.205271e-19	3.9925026877011495e-17	2.684264	109	0.002688968	495	0.03638377083434343	1.279261	24	24	0.0016351	
Mouse Phenotype Single KO	extramedullary hematopoiesis	1	5.169432e-76	4.7336488824e-72	2.121249	751	0.01852674	255	0.018046963925098036	1.155824	103	114	0.007017305	
Mouse Phenotype	abnormal cerebral artery morphology	198	1.810936e-20	8.744625806060606e-19	2.203737	174	0.004292481	512	0.050399373615234375	1.279261	24	24	0.0016351	
Mouse Phenotype	increased cellular sensitivity to ultraviolet irradiation	268	4.827609e-17	1.722267524216418e-15	2.146269	151	0.003725084	360	0.016315788071666667	1.279261	30	30	0.002043875