# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	viral gene expression	38	4.116362e-30	1.425452830473684e-27	2.270024	246	0.01363259	179	1.5447261883240224e-9	1.478504	108	127	0.01	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	69	2.531824e-24	4.828445219710145e-22	2.180423	214	0.01185924	233	1.509047576094421e-7	1.443931	98	118	0.009074074	
GO Biological Process	translational elongation	70	5.879545e-24	1.1052704665000002e-21	2.173772	212	0.01174841	396	0.00019452391439393939	1.350528	87	112	0.008055556	
GO Biological Process	viral transcription	73	3.617112e-23	6.52021600109589e-21	2.131088	214	0.01185924	207	1.967487273864734e-8	1.47705	96	113	0.008888889	
GO Biological Process	mitochondrial transmembrane transport	80	1.49683e-21	2.4620982462500003e-19	2.200634	184	0.01019673	205	1.7613193119512195e-8	1.550087	74	83	0.006851852	
GO Biological Process	cotranslational protein targeting to membrane	83	3.173947e-21	5.032044406385543e-19	2.206032	180	0.009975062	267	0.0000013205943623595507	1.454756	82	98	0.007592593	
GO Biological Process	protein targeting to ER	84	5.132626e-21	8.040503039761906e-19	2.163643	186	0.01030756	274	0.0000015431612128102192	1.445974	84	101	0.007777778	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	86	1.754747e-20	2.6849669503488372e-18	2.224616	170	0.009420892	291	0.000003154361073573883	1.455142	77	92	0.00712963	
GO Biological Process	chaperone-mediated protein folding	88	4.596029e-20	6.872630183068182e-18	2.335176	150	0.008312552	612	0.006912508706535947	1.364141	51	65	0.004722222	
GO Biological Process	mitochondrial translational termination	109	7.1201e-18	8.595724394495413e-16	2.207144	149	0.008257135	477	0.0011628773822012577	1.358914	68	87	0.006296296	
GO Biological Process	mitochondrial translation	116	3.22359e-17	3.6568293801724135e-15	2.007614	179	0.009919645	364	0.00005033686241208792	1.38114	85	107	0.00787037	
GO Biological Process	cytoplasmic translation	120	7.043341e-17	7.723610351583333e-15	2.79749	89	0.004932114	491	0.0015385824404887984	1.496014	37	43	0.003425926	
GO Biological Process	mitochondrial translational elongation	122	1.013005e-16	1.0926338356557377e-14	2.168443	144	0.00798005	516	0.0020169429197868217	1.34998	66	85	0.006111111	
GO Biological Process	snRNA metabolic process	137	1.088335e-15	1.0453576835766423e-13	2.056568	152	0.008423386	556	0.0035325122494604317	1.334283	66	86	0.006111111	
GO Biological Process	translational termination	141	1.195434e-15	1.1156536174468085e-13	2.002568	162	0.008977556	412	0.000282422162961165	1.372588	75	95	0.006944444	
GO Biological Process	cytoplasmic sequestering of protein	142	1.280906e-15	1.187002961549296e-13	2.832257	80	0.004433361	891	0.0501108307295174	1.381973	31	39	0.00287037	
GO Biological Process	activation of JUN kinase activity	152	4.807464e-15	4.161935445789474e-13	2.08663	140	0.007758382	878	0.04762092225284738	1.400548	29	36	0.002685185	
GO Biological Process	protein transmembrane transport	164	2.568837e-14	2.0611784196951217e-12	2.033649	141	0.007813799	365	0.000050575733224657533	1.490238	54	63	0.005	
GO Biological Process	intracellular protein transmembrane import	174	8.081204e-14	6.111526634252873e-12	2.241907	108	0.005985037	360	0.000044611714905555555	1.580556	40	44	0.003703704	
GO Biological Process	intracellular protein transmembrane transport	181	1.351677e-13	9.826915824861878e-12	2.065369	128	0.007093378	358	0.00004293936079329609	1.521285	49	56	0.004537037	
GO Cellular Component	mitochondrial ribosome	36	5.232481e-19	2.5115908800000003e-17	2.380404	136	0.007536714	214	0.01866655042990654	1.268163	62	85	0.005740741	
GO Cellular Component	PRC1 complex	38	7.62993e-18	3.469610273684211e-16	5.429034	42	0.002327515	197	0.011468850030456853	1.738611	12	12	0.001111111	
GO Cellular Component	COPI-coated vesicle	42	2.231147e-15	9.179576228571429e-14	3.022007	71	0.003934608	101	0.00005061033124752475	1.738611	23	23	0.00212963	
GO Cellular Component	endopeptidase complex	48	2.684839e-14	9.665420400000001e-13	2.068589	135	0.007481297	115	0.00012354914504347826	1.436244	57	69	0.005277778	
GO Cellular Component	proteasome complex	51	5.394994e-14	1.827950908235294e-12	2.054426	134	0.00742588	117	0.00017577363692307694	1.431797	56	68	0.005185185	
GO Cellular Component	MLL1 complex	52	1.932074e-13	6.420430523076923e-12	2.725288	72	0.003990025	152	0.002091327915789474	1.558755	26	29	0.002407407	
GO Cellular Component	nuclear ubiquitin ligase complex	55	7.439873e-13	2.337472826181818e-11	2.449468	83	0.004599612	137	0.0005398154697810218	1.521285	35	40	0.003240741	
GO Cellular Component	spliceosomal snRNP complex	67	1.316457e-10	3.395280143283582e-9	2.016136	102	0.005652535	130	0.00041540162953846154	1.430148	51	62	0.004722222	
GO Cellular Component	COPI-coated vesicle membrane	70	2.267442e-10	5.5973425371428575e-9	2.766737	52	0.002881685	146	0.0016900526465753424	1.738611	16	16	0.001481481	
GO Cellular Component	mitochondrial nucleoid	71	3.038825e-10	7.395900845070423e-9	2.148204	84	0.004655029	196	0.010508073795918367	1.407447	34	42	0.003148148	
GO Cellular Component	COPI vesicle coat	97	3.284241e-8	5.850689121649485e-7	2.527937	46	0.002549183	182	0.007136860272527473	1.738611	13	13	0.001203704	
GO Cellular Component	outer mitochondrial membrane protein complex	113	1.157464e-7	0.000001769998046017699	2.923056	33	0.001828761	220	0.023596248436363636	1.622704	14	15	0.001296296	
GO Cellular Component	prespliceosome	124	2.90246e-7	0.000004044718451612903	2.446804	42	0.002327515	193	0.010545939233160622	1.573029	19	21	0.001759259	
GO Cellular Component	spliceosomal tri-snRNP complex	129	4.723911e-7	0.000006327843572093023	2.187979	51	0.002826268	188	0.00867086410212766	1.498803	25	29	0.002314815	
GO Cellular Component	proteasome accessory complex	135	0.000001117945	0.000014309696000000002	2.243878	45	0.002493766	249	0.049259256289156624	1.448843	20	24	0.001851852	
GO Cellular Component	STAGA complex	144	0.000002005192	0.000024062304000000003	2.880919	27	0.001496259	197	0.011468850030456853	1.738611	12	12	0.001111111	
GO Cellular Component	proteasome regulatory particle	164	0.00001035056	0.00010905955902439023	2.111434	42	0.002327515	237	0.04375888769620253	1.490238	18	21	0.001666667	
GO Cellular Component	exon-exon junction complex	165	0.00001040804	0.00010900056436363637	2.110924	42	0.002327515	193	0.010545939233160622	1.573029	19	21	0.001759259	
GO Cellular Component	U2-type prespliceosome	169	0.00001342884	0.0001373079024852071	2.364222	32	0.001773344	202	0.015677288554455444	1.629948	15	16	0.001388889	
GO Cellular Component	preribosome, large subunit precursor	171	0.00001501274	0.00015170768842105264	2.002268	46	0.002549183	234	0.035416157538461536	1.460433	21	25	0.001944444	
GO Molecular Function	unfolded protein binding	8	2.087163e-30	1.10150027325e-27	2.444302	214	0.01185924	81	0.00010103183451851851	1.377767	84	106	0.007777778	
GO Molecular Function	ribonucleoprotein complex binding	10	1.290657e-22	5.449153854e-20	2.027887	235	0.013023	40	3.334216839e-9	1.496717	99	115	0.009166667	
GO Molecular Function	rRNA binding	11	1.548422e-21	5.9431251672727275e-19	2.963929	106	0.005874203	126	0.006868825412698412	1.390889	48	60	0.004444444	
GO Molecular Function	DNA polymerase binding	13	2.669517e-17	8.669769826153845e-15	4.771018	46	0.002549183	122	0.004941601832786886	1.738611	16	16	0.001481481	
GO Molecular Function	snRNA binding	41	4.08433e-11	4.20586372195122e-9	2.55109	65	0.003602106	138	0.013177171001449274	1.464094	32	38	0.002962963	
GO Molecular Function	S-acyltransferase activity	57	1.387195e-9	1.0274977701754385e-7	2.221139	72	0.003990025	119	0.004144428732773109	1.56475	27	30	0.0025	
GO Molecular Function	mRNA 5'-UTR binding	64	4.926828e-9	3.25016684625e-7	2.380718	58	0.003214187	118	0.0031827561311864407	1.659583	21	22	0.001944444	
Human Phenotype	Exercise intolerance	2	3.445458e-15	1.1495770617e-11	2.17863	128	0.007093378	134	0.00028209006952985077	1.440563	58	70	0.00537037	
Human Phenotype	Abnormal CSF metabolite level	9	5.397339e-13	4.0018270163333335e-10	2.129688	113	0.006262122	136	0.00028560474346323527	1.462641	53	63	0.004907407	
Human Phenotype	Increased CSF lactate	21	7.943488e-11	2.5241378773333337e-8	2.060302	99	0.005486284	182	0.0014385184090109887	1.438851	48	58	0.004444444	
Human Phenotype	Tethered cord	33	2.110169e-9	4.267017496060606e-7	2.938479	42	0.002327515	365	0.04157778103835617	1.738611	11	11	0.001018519	
Human Phenotype	Progressive external ophthalmoplegia	46	2.048428e-8	0.000002971556531304348	2.7453	41	0.002272098	236	0.007023883870762713	1.738611	15	15	0.001388889	
Human Phenotype	Abnormal mitochondria in muscle tissue	69	3.64843e-7	0.0000352840194057971	2.317238	46	0.002549183	377	0.04576792986737401	1.511836	20	23	0.001851852