# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	chromatin assembly or disassembly	47	4.476938e-11	1.2534473860000001e-8	2.984316	49	0.03337875	152	0.02218994378486842	1.843288	35	178	0.01747379	
GO Biological Process	nucleosome organization	49	1.800243e-10	4.83457094632653e-8	2.981286	46	0.03133515	177	0.03993320840451978	1.809102	33	171	0.01647529	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	52	6.945364e-10	1.7575777860769232e-7	3.452744	35	0.02384196	115	0.004966039537913043	2.23991	27	113	0.01347978	
GO Biological Process	regulation of DNA-templated transcription in response to stress	55	1.37699e-9	3.294511165454546e-7	3.226789	37	0.02520436	99	0.002048654262828283	2.284527	29	119	0.01447828	
GO Biological Process	mRNA splicing, via spliceosome	56	3.181407e-9	7.475738341607142e-7	2.254383	65	0.04427793	104	0.0024672074810576923	1.776209	54	285	0.02695956	
GO Biological Process	RNA splicing, via transesterification reactions	57	3.531188e-9	8.152088226666667e-7	2.248135	65	0.04427793	109	0.0031879862618348627	1.757707	54	288	0.02695956	
GO Biological Process	macromolecular complex disassembly	64	4.710024e-8	0.00000968425090875	2.535884	44	0.02997275	131	0.01111550775038168	1.865072	38	191	0.01897154	
GO Biological Process	protein-DNA complex subunit organization	72	7.805042e-8	0.00001426479828861111	2.187771	57	0.03882834	183	0.04248917419781421	1.649901	44	250	0.02196705	
GO Biological Process	translational elongation	73	7.827418e-8	0.000014109725131780822	3.403084	27	0.01839237	153	0.022282048693464052	2.092509	25	112	0.01248128	
GO Biological Process	translation	79	1.765921e-7	0.000029414879036708857	2.016607	65	0.04427793	193	0.04995057537046632	1.512006	60	372	0.02995507	
GO Biological Process	histone H4-K5 acetylation	82	2.854324e-7	0.00004580493843414634	7.826795	11	0.007493188	93	0.0006830869443763441	5.624663	9	15	0.00449326	
GO Biological Process	histone H4-K8 acetylation	82	2.854324e-7	0.00004580493843414634	7.826795	11	0.007493188	93	0.0006830869443763441	5.624663	9	15	0.00449326	
GO Biological Process	regulation of mRNA processing	96	8.724205e-7	0.00011958522249479166	2.559463	35	0.02384196	102	0.0023699565415686275	2.302494	28	114	0.01397903	
GO Biological Process	cellular response to oxygen levels	97	8.782644e-7	0.0001191451674185567	2.071092	54	0.03678474	155	0.0227123915516129	1.774772	39	206	0.01947079	
GO Biological Process	regulation of mRNA metabolic process	110	0.00000189446	0.0002266290830909091	2.306753	40	0.02724796	113	0.004912036936017699	2.083209	32	144	0.01597604	
GO Biological Process	regulation of RNA splicing	115	0.000002447438	0.0002800507534086956	2.310155	39	0.02656676	91	0.000643615077054945	2.383332	30	118	0.01497753	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to hypoxia	125	0.000004211277	0.00044332955234400003	3.142458	22	0.01498638	168	0.034007626137500004	2.283517	19	78	0.009485771	
GO Biological Process	regulation of signal transduction by p53 class mediator	138	0.000007217888	0.0006882622332753623	2.177185	40	0.02724796	163	0.03169191762883436	1.821319	34	175	0.01697454	
GO Biological Process	regulation of mRNA splicing, via spliceosome	142	0.00000920057	0.0008526077509154929	2.576652	28	0.01907357	119	0.0063718863655462185	2.491939	21	79	0.01048427	
GO Biological Process	protein complex disassembly	146	0.00001336626	0.0012047028447945206	2.316026	33	0.02247956	187	0.045810813729411766	1.827721	31	159	0.01547678	
GO Cellular Component	intracellular ribonucleoprotein complex	18	1.103078e-18	1.0589548800000001e-16	2.143767	157	0.1069482	21	0.000014208858514285716	1.543212	134	814	0.06689965	
GO Cellular Component	ribonucleoprotein complex	19	1.235391e-18	1.123555604210526e-16	2.141038	157	0.1069482	20	0.0000107312256	1.54902	135	817	0.0673989	
GO Cellular Component	spliceosomal complex	47	0.000005602376	0.0002059767176170213	2.227635	39	0.02656676	32	0.007328718	1.864808	37	186	0.01847229	
GO Cellular Component	mediator complex	53	0.0000227968	0.0007432617056603774	3.508027	16	0.01089918	31	0.0026961103277419354	3.385214	13	36	0.006490265	
GO Cellular Component	histone methyltransferase complex	79	0.0005104679	0.011165677610126582	2.486895	18	0.01226158	39	0.03289267052307692	2.309644	17	69	0.008487269	
GO Molecular Function	ribonucleoprotein complex binding	8	1.515016e-9	7.99549694e-7	3.500424	33	0.02247956	46	0.036473858000000005	2.037921	25	115	0.01248128	
GO Molecular Function	histone binding	13	1.727195e-7	0.00005609397915384615	2.205702	53	0.03610354	43	0.023525465111627907	1.799135	38	198	0.01897154	
GO Molecular Function	protein N-terminus binding	16	9.401723e-7	0.0002480879656625	2.637452	33	0.02247956	31	0.011880880965806454	2.232009	25	105	0.01248128	
GO Molecular Function	histone acetyltransferase activity (H4-K5 specific)	22	0.000006035178	0.0011582055234545454	10.6022	7	0.004768392	33	0.011813889092727271	6.249626	6	9	0.002995507	
GO Molecular Function	histone acetyltransferase activity (H4-K8 specific)	22	0.000006035178	0.0011582055234545454	10.6022	7	0.004768392	33	0.011813889092727271	6.249626	6	9	0.002995507	
GO Molecular Function	histone acetyltransferase activity (H4-K16 specific)	22	0.000006035178	0.0011582055234545454	10.6022	7	0.004768392	33	0.011813889092727271	6.249626	6	9	0.002995507	
Mouse Phenotype Single KO	abnormal induced cell death	5	3.110206e-7	0.00056960312684	2.181643	52	0.03542234	78	0.02564156053717949	1.777145	40	211	0.01997004	
Mouse Phenotype Single KO	increased mean corpuscular volume	8	7.421245e-7	0.0008494542558125	2.430751	39	0.02656676	85	0.026747629318823525	2.003697	28	131	0.01397903	
Mouse Phenotype Single KO	increased cellular sensitivity to oxidative stress	10	0.000002034225	0.0018627398325	4.544869	15	0.01021798	81	0.025640527004938272	3.124813	12	36	0.005991013	
Mouse Phenotype Single KO	thin interventricular septum	13	0.00001267807	0.00893023746076923	4.782993	12	0.008174387	53	0.010333933660377359	4.440523	9	19	0.00449326	
Mouse Phenotype Single KO	pale placenta	21	0.00006230028	0.027165888760000003	5.382198	9	0.00613079	67	0.02037495368955224	5.047774	7	13	0.003494758	
Mouse Phenotype Single KO	failure to gastrulate	26	0.0001219176	0.042938440892307694	2.56431	21	0.01430518	92	0.03040070252391304	2.653143	15	53	0.007488767	
Mouse Phenotype	pale placenta	38	0.00009409076	0.023673730430526316	5.093848	9	0.00613079	136	0.03240004965441176	4.374738	7	15	0.003494758	
Mouse Phenotype	abnormal Paneth cell morphology	41	0.0001586231	0.03699013314878049	2.661085	19	0.01294278	128	0.02993231644921875	2.960349	12	38	0.005991013	
Mouse Phenotype	abnormal cell adhesion	42	0.000176659	0.0402151595	2.199383	27	0.01839237	179	0.046393849813407814	2.220262	18	76	0.00898652