# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	liver regeneration	6	2.290411e-29	5.023253058166667e-26	4.671631	83	0.01339574	313	0.011037214251757188	2.048828	20	35	0.00381898	
GO Biological Process	rRNA processing	24	4.695395e-19	2.5744459502083333e-16	2.131911	171	0.02759845	156	0.00006847831411089744	1.508165	106	252	0.0202406	
GO Biological Process	rRNA metabolic process	25	8.93061e-19	4.700715879600001e-16	2.101388	174	0.02808263	149	0.000048950102279194626	1.508934	109	259	0.02081344	
GO Biological Process	regulation of cellular amino acid metabolic process	28	6.683024e-18	3.1407826005714284e-15	3.818428	61	0.009845061	355	0.02219391379859155	1.732967	29	60	0.005537521	
GO Biological Process	regulation of intrinsic apoptotic signaling pathway	29	1.206582e-17	5.474969840689655e-15	2.225027	143	0.02307941	272	0.005447613133823529	1.503576	65	155	0.01241169	
GO Biological Process	mitochondrial membrane organization	37	1.295185e-15	4.606307949999999e-13	2.216744	126	0.0203357	168	0.0001818817398154762	1.70598	59	124	0.01126599	
GO Biological Process	regulation of hematopoietic progenitor cell differentiation	44	7.576012e-15	2.265744134272727e-12	2.584042	88	0.01420271	243	0.0035015855314814814	1.618212	51	113	0.0097384	
GO Biological Process	cellular response to topologically incorrect protein	46	8.96894e-15	2.5657017708695654e-12	2.256759	114	0.01839897	397	0.03460419246851385	1.444498	56	139	0.01069314	
GO Biological Process	endoplasmic reticulum unfolded protein response	54	1.475726e-14	3.5961256359259256e-12	2.411047	98	0.01581666	429	0.04424049665268066	1.478212	47	114	0.008974604	
GO Biological Process	regulation of mitochondrial membrane permeability	58	2.067601e-14	4.6909588894827586e-12	2.552822	87	0.01404132	255	0.004229472376901961	1.768167	36	73	0.006874165	
GO Biological Process	DNA-templated transcription, elongation	63	5.919569e-14	1.2364382296984127e-11	2.518746	86	0.01387992	351	0.02153060958888889	1.531965	47	110	0.008974604	
GO Biological Process	nuclear-transcribed mRNA catabolic process	70	1.218613e-13	2.2908183524285712e-11	2.011272	136	0.02194964	263	0.004584160802623574	1.448667	80	198	0.01527592	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	75	1.964074e-13	3.446033302133334e-11	2.492596	84	0.01355713	390	0.03238997424051282	1.488873	49	118	0.009356502	
GO Biological Process	mitochondrial translational termination	77	2.590034e-13	4.426267195584416e-11	2.847304	66	0.01065203	198	0.0010772442555050505	1.772119	43	87	0.008210808	
GO Biological Process	cellular response to unfolded protein	81	3.874136e-13	6.293796990617283e-11	2.234939	102	0.01646223	344	0.019373991874709305	1.511223	51	121	0.0097384	
GO Biological Process	translational termination	85	6.398157e-13	9.905099760352943e-11	2.628092	73	0.01178179	182	0.0004662831639175825	1.773854	47	95	0.008974604	
GO Biological Process	regulation of membrane permeability	92	1.233376e-12	1.764129867826087e-10	2.322441	90	0.0145255	256	0.004244014978828124	1.726328	39	81	0.007447012	
GO Biological Process	regulation of hematopoietic stem cell differentiation	95	1.469095e-12	2.0349285373684212e-10	2.524381	76	0.01226598	329	0.016602814292097264	1.566459	45	103	0.008592706	
GO Biological Process	mRNA transport	96	1.806072e-12	2.4756355675e-10	2.051328	117	0.01888315	158	0.00009050368761392404	1.669935	68	146	0.01298453	
GO Biological Process	mitochondrial translational elongation	97	3.056092e-12	4.145888105979382e-10	2.762941	63	0.01016785	279	0.00598685448530466	1.68727	40	85	0.007637961	
GO Cellular Component	peptidase complex	34	5.536727e-18	2.8139600752941177e-16	2.912868	89	0.01436411	53	0.00010645956950943396	1.833469	45	88	0.008592706	
GO Cellular Component	proteasome complex	37	5.901798e-17	2.756299174054054e-15	3.214872	72	0.0116204	59	0.0009590965261016949	1.845452	35	68	0.006683216	
GO Cellular Component	endopeptidase complex	38	6.071588e-17	2.7609747536842107e-15	3.213057	72	0.0116204	62	0.0013582054916129033	1.818706	35	69	0.006683216	
GO Cellular Component	mitochondrial ribosome	42	1.676642e-14	6.89818422857143e-13	3.16045	62	0.01000646	69	0.003178883895652174	1.68727	40	85	0.007637961	
GO Cellular Component	ribosomal subunit	45	6.884128e-14	2.6435051519999995e-12	2.160807	117	0.01888315	61	0.0010732984760655736	1.492322	77	185	0.01470307	
GO Cellular Component	PcG protein complex	47	3.234296e-13	1.1891198910638298e-11	2.733569	70	0.01129761	52	0.00009798205292307693	2.182448	28	46	0.005346572	
GO Cellular Component	large ribosomal subunit	48	6.665677e-13	2.3996437200000003e-11	2.48018	81	0.01307295	68	0.0028583813647058824	1.590069	51	115	0.0097384	
GO Cellular Component	nuclear ubiquitin ligase complex	50	1.692781e-11	5.850251136e-10	3.523895	41	0.006617172	72	0.0066356784	1.971997	22	40	0.004200878	
GO Cellular Component	methyltransferase complex	53	5.730589e-11	1.868388262641509e-9	2.259165	81	0.01307295	54	0.00012277792	1.812425	46	91	0.008783655	
GO Cellular Component	mitochondrial large ribosomal subunit	54	6.436486e-11	2.05967552e-9	3.430509	40	0.006455778	87	0.021459833379310345	1.757573	25	51	0.004773725	
GO Cellular Component	nuclear pore	58	6.667474e-10	1.9864474262068964e-8	2.242279	73	0.01178179	44	0.000011199018763636362	2.007852	42	75	0.008019859	
GO Cellular Component	proteasome regulatory particle, lid subcomplex	66	1.840163e-8	4.817881309090909e-7	8.040339	13	0.002098128	101	0.0428177184950495	3.073243	6	7	0.001145694	
GO Cellular Component	histone methyltransferase complex	76	1.698548e-7	0.000003861961768421052	2.062244	63	0.01016785	62	0.0013582054916129033	1.818706	35	69	0.006683216	
GO Cellular Component	preribosome	91	0.000001003854	0.00001906219463736264	2.10967	52	0.008392511	67	0.002394197129552239	1.745548	37	76	0.007065114	
GO Cellular Component	Bcl-2 family protein complex	128	0.0000322645	0.00043557075	4.045322	13	0.002098128	101	0.0428177184950495	3.073243	6	7	0.001145694	
GO Cellular Component	tubular endosome	165	0.0001291572	0.001352628130909091	6.511563	7	0.001129761	97	0.03002310927835052	3.58545	5	5	0.0009547451	
GO Cellular Component	U1 snRNP	235	0.001580045	0.011618373446808512	2.384822	16	0.002582311	93	0.026093636129032257	2.264495	12	19	0.002291388	
GO Cellular Component	ripoptosome	252	0.003484776	0.023895606857142856	4.209732	6	0.0009683667	101	0.0428177184950495	3.073243	6	7	0.001145694	
GO Molecular Function	unfolded protein binding	5	1.604855e-16	1.355139562e-13	2.827519	85	0.01371853	43	0.009287960126511627	1.6236	48	106	0.009165553	
GO Molecular Function	NF-kappaB binding	11	1.196029e-14	4.590576761818182e-12	4.093064	45	0.00726275	58	0.02051551328275862	2.17688	17	28	0.003246133	
GO Molecular Function	structural constituent of ribosome	17	4.373917e-11	1.0862751514117648e-8	2.052851	102	0.01646223	41	0.007886529179512195	1.505004	68	162	0.01298453	
GO Molecular Function	heat shock protein binding	23	1.794463e-10	3.294009906956522e-8	2.022705	99	0.01597805	36	0.0036136133183333335	1.67321	49	105	0.009356502	
GO Molecular Function	SUMO binding	28	2.082318e-9	3.13983807e-7	3.851293	29	0.004680439	76	0.049243941410526314	2.561035	10	14	0.00190949	
GO Molecular Function	ubiquitin-protein transferase regulator activity	200	0.0008219875	0.017352156125	2.089382	24	0.003873467	60	0.021800289963333334	2.530906	12	17	0.002291388	
Human Phenotype	Increased serum lactate	19	6.476436e-10	2.2745924962105263e-7	2.229754	74	0.01194319	57	0.04646989397368421	1.577598	44	100	0.008401757	
Human Phenotype	Infantile encephalopathy	31	6.866291e-8	0.000014780245110645162	9.06972	11	0.001775339	61	0.05138449571639345	3.58545	6	6	0.001145694	
Human Phenotype	Papule	130	0.0001036796	0.005321953621538461	3.227093	15	0.002420917	61	0.05138449571639345	3.58545	6	6	0.001145694	
Mouse Phenotype	abnormal kidney inner medulla morphology	330	0.0002816469	0.008160078820909092	2.216639	25	0.004034861	94	0.02511990009574468	3.187066	8	9	0.001527592