# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	posttranscriptional regulation of gene expression	4	1.542587e-19	5.07472558325e-16	2.006158	197	0.07962813	23	0.0000075914557065217385	1.626976	125	557	0.04826255	
GO Biological Process	liver regeneration	17	5.175836e-14	4.006401524941176e-11	4.933671	35	0.01414713	104	0.0031954126228846158	3.10706	15	35	0.005791506	
GO Biological Process	RNA splicing, via transesterification reactions	21	4.886188e-12	3.0617784710476194e-9	2.113842	103	0.04163298	61	0.00022782284560655738	1.762106	70	288	0.02702703	
GO Biological Process	mRNA splicing, via spliceosome	26	9.134363e-12	4.623041642961539e-9	2.099138	102	0.04122878	67	0.0002869734360298508	1.755216	69	285	0.02664093	
GO Biological Process	negative regulation of translation	35	3.674389e-10	1.3814652814571427e-7	2.309848	70	0.02829426	75	0.00043554219650666665	2.078616	41	143	0.01583012	
GO Biological Process	negative regulation of cellular amide metabolic process	36	4.078839e-10	1.4909289555833332e-7	2.257819	73	0.02950687	65	0.0002431831787076923	2.071373	44	154	0.01698842	
GO Biological Process	mitochondrial transport	43	1.425549e-9	4.362511463023256e-7	2.10353	80	0.0323363	123	0.007822899259186993	1.668366	55	239	0.02123552	
GO Biological Process	regulation of intrinsic apoptotic signaling pathway	51	4.186892e-9	0.0000010803002319215686	2.338096	60	0.02425222	136	0.01063860641617647	1.824145	39	155	0.01505792	
GO Biological Process	mitochondrial membrane organization	96	1.904899e-7	0.000026111006188541668	2.247124	51	0.02061439	161	0.021871712845962732	1.870918	32	124	0.01235521	
GO Biological Process	RNA phosphodiester bond hydrolysis, endonucleolytic	104	3.165909e-7	0.00004005788127980769	3.09396	28	0.0113177	166	0.02701415073554217	2.174942	21	70	0.008108108	
GO Biological Process	positive regulation of intrinsic apoptotic signaling pathway	144	0.000001967312	0.0001797767958888889	2.946087	26	0.0105093	100	0.0021879416664	2.685114	20	54	0.007722008	
GO Biological Process	regulation of mitochondrial membrane permeability	146	0.00000219848	0.00019814930356164384	2.498572	34	0.01374293	155	0.01963563057870968	2.184873	22	73	0.008494208	
GO Biological Process	morphogenesis of an endothelium	155	0.000002591004	0.00021996788152258063	3.486939	20	0.008084074	187	0.04170022360534759	3.624903	8	16	0.003088803	
GO Biological Process	regulation of cell differentiation involved in embryonic placenta development	197	0.000006359967	0.000424826425142132	8.541633	8	0.00323363	168	0.028296980443452382	7.249807	4	4	0.001544402	
GO Biological Process	regulation of membrane permeability	221	0.00001276567	0.0007601061155203619	2.261944	35	0.01414713	179	0.03238227001452514	2.058587	23	81	0.008880309	
GO Biological Process	mitochondrial calcium ion transport	338	0.000099651	0.003879608014792899	3.851974	12	0.004850445	139	0.014020393820143884	3.322828	11	24	0.004247104	
GO Biological Process	negative regulation of DNA binding	343	0.0001092902	0.004192856390087463	2.103694	32	0.01293452	159	0.019695282202515724	2.464934	17	50	0.006563707	
GO Biological Process	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	358	0.0001448991	0.005326053790223463	2.472343	22	0.008892482	162	0.021741616590740743	2.521672	16	46	0.006177606	
GO Biological Process	circadian regulation of translation	460	0.0004188832	0.011982791366956522	6.413093	6	0.002425222	168	0.028296980443452382	7.249807	4	4	0.001544402	
GO Biological Process	positive regulation of phosphoprotein phosphatase activity	534	0.0009917441	0.02443887755037453	2.416279	17	0.006871463	187	0.04170022360534759	3.624903	8	16	0.003088803	
GO Cellular Component	intracellular ribonucleoprotein complex	15	3.100603e-27	3.5718946560000004e-25	2.07417	256	0.1034762	21	0.00004507177782857143	1.442836	162	814	0.06254826	
GO Cellular Component	ribonucleoprotein complex	16	3.707569e-27	4.0041745199999996e-25	2.071529	256	0.1034762	22	0.000054463096145454544	1.437538	162	817	0.06254826	
GO Cellular Component	peptidase complex	27	1.767748e-11	1.13135872e-9	3.442641	42	0.01697656	42	0.02624560457142857	1.97722	24	88	0.009266409	
GO Cellular Component	methyltransferase complex	37	1.934117e-9	9.032849124324324e-8	2.933756	42	0.01697656	46	0.04019790052173913	1.912037	24	91	0.009266409	
GO Cellular Component	spliceosomal complex	40	3.923687e-9	1.6950327840000002e-7	2.236917	66	0.02667745	49	0.049109654204081636	1.598076	41	186	0.01583012	
GO Cellular Component	Bcl-2 family protein complex	64	0.000008159506	0.000220306662	7.013972	9	0.003637833	45	0.03146338944	5.178434	5	7	0.001930502	
GO Molecular Function	deoxyribonucleotide binding	4	9.651792e-16	1.0187466455999999e-12	39.4485	12	0.004850445	27	0.007781723006666667	7.249807	5	5	0.001930502	
GO Molecular Function	purine deoxyribonucleotide binding	12	5.964638e-10	2.0985584696666666e-7	29.28998	8	0.00323363	38	0.04013849844736842	7.249807	4	4	0.001544402	
GO Molecular Function	disordered domain specific binding	25	9.860993e-7	0.000166532449784	3.339423	23	0.009296686	23	0.004197093871304348	3.274106	14	31	0.005405405	
Mouse Phenotype Single KO	absent chorion	51	0.000005844186	0.0010493178667058823	3.738687	17	0.006871463	80	0.038571619035	3.866564	8	15	0.003088803	
Mouse Phenotype Single KO	abnormal amnion morphology	70	0.0000341595	0.004468550592857143	2.395051	28	0.0113177	57	0.018248101729824565	2.788387	15	39	0.005791506	
Mouse Phenotype Single KO	abnormal branching of the mammary ductal tree	94	0.00009891311	0.009635610087978724	2.210605	29	0.01172191	49	0.014959331181224488	2.861766	15	38	0.005791506	
Mouse Phenotype Single KO	absent segment of posterior cerebral artery	116	0.0002094271	0.01653210305775862	3.338161	13	0.005254648	77	0.038493768480519476	3.295367	10	22	0.003861004	
Mouse Phenotype Single KO	disorganized yolk sac vascular plexus	127	0.0002553515	0.018411446342519688	2.735177	17	0.006871463	90	0.04520101741222223	3.434119	9	19	0.003474903	
Mouse Phenotype Single KO	abnormal vertebral transverse process morphology	160	0.0006127424	0.03506801348	3.602355	10	0.004042037	86	0.04210195877093023	4.833205	6	9	0.002316602	
Mouse Phenotype	absent epidermis stratum corneum	10	3.576543e-9	0.0000034195327622999997	7.526978	15	0.006063056	99	0.018027970503030302	4.613514	7	11	0.002702703	
Mouse Phenotype	increased pre-B cell number	31	0.00000102819	0.0003171136964516129	2.909744	28	0.0113177	67	0.007918560047462686	2.939111	15	37	0.005791506	
Mouse Phenotype	absent chorion	34	0.000001393956	0.00039198862694117645	3.79147	19	0.007679871	108	0.02357843521666667	3.624903	9	18	0.003474903	
Mouse Phenotype	abnormal amnion morphology	145	0.0001854602	0.012228861877241379	2.096818	30	0.01212611	127	0.0349442203511811	2.416602	16	48	0.006177606	
Mouse Phenotype	absent segment of posterior cerebral artery	149	0.0002094271	0.013438473175167784	3.338161	13	0.005254648	116	0.02667922869827586	3.295367	10	22	0.003861004