# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	ncRNA metabolic process	3	8.142074e-30	3.5713850588666665e-26	2.181566	257	0.06658031	61	1.1505015089016395e-7	1.559752	165	555	0.04610226	
GO Biological Process	ncRNA processing	10	9.506483e-23	1.25095809797e-19	2.236743	184	0.04766839	73	9.353521750958904e-7	1.629575	123	396	0.03436714	
GO Biological Process	ribonucleoprotein complex biogenesis	12	2.000568e-22	2.193789526e-19	2.039401	223	0.05777202	40	3.84933318525e-9	1.68718	146	454	0.04079352	
GO Biological Process	rRNA processing	17	4.647939e-19	3.597778194176471e-16	2.481526	124	0.03212435	98	0.000028250103743877552	1.707174	82	252	0.02291143	
GO Biological Process	rRNA metabolic process	18	8.0882e-19	5.912923544444445e-16	2.442596	126	0.03264249	105	0.00004608581323904761	1.681291	83	259	0.02319084	
GO Biological Process	gene silencing	21	1.99322e-16	1.2489896180952382e-13	2.568792	99	0.02564767	123	0.0003865610306585366	1.748813	60	180	0.01676446	
GO Biological Process	ribosome biogenesis	22	2.378959e-16	1.4229418854999998e-13	2.102951	148	0.03834197	112	0.0001362749564732143	1.575556	97	323	0.02710254	
GO Biological Process	regulation of gene expression, epigenetic	27	1.593099e-14	7.764292496666666e-12	2.131178	126	0.03264249	119	0.00020384418914285712	1.650089	78	248	0.0217938	
GO Biological Process	chromatin silencing	29	1.331471e-13	6.041664444482759e-11	3.555892	49	0.0126943	203	0.022271639911330045	1.784871	33	97	0.009220453	
GO Biological Process	negative regulation of gene expression, epigenetic	30	2.265924e-13	9.939097972e-11	2.966176	62	0.01606218	156	0.003290008118846154	1.840855	40	114	0.01117631	
GO Biological Process	RNA catabolic process	42	1.564417e-11	4.901467453095238e-9	2.022639	110	0.02849741	184	0.013689293396739131	1.502092	69	241	0.01927913	
GO Biological Process	cotranslational protein targeting to membrane	43	1.572601e-11	4.812524781162791e-9	2.979286	52	0.0134715	166	0.006077332742228915	1.873728	35	98	0.009779268	
GO Biological Process	mRNA catabolic process	45	2.536973e-11	7.4186728237777774e-9	2.103684	98	0.0253886	237	0.04205712455147679	1.47787	60	213	0.01676446	
GO Biological Process	cargo loading into vesicle	48	3.356222e-11	9.200942770416667e-9	5.384013	25	0.006476684	178	0.011941208476966291	3.279023	10	16	0.002794077	
GO Biological Process	tRNA metabolic process	52	2.099428e-10	5.3127640484615384e-8	2.122855	87	0.02253886	254	0.04898506653425197	1.498982	54	189	0.01508801	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	57	4.275172e-10	9.869647078596493e-8	2.619747	55	0.0142487	185	0.014866796358918919	1.733992	39	118	0.0108969	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	58	4.419138e-10	1.0026109817586206e-7	2.875236	47	0.01217617	191	0.018369247489005234	1.824848	32	92	0.008941045	
GO Biological Process	viral gene expression	59	7.674538e-10	1.7116821278305087e-7	2.502032	58	0.01502591	161	0.004417630775217391	1.776353	43	127	0.01201453	
GO Biological Process	protein targeting to ER	77	5.902714e-9	0.000001008750825012987	2.610258	48	0.01243523	239	0.042781087253556484	1.714183	33	101	0.009220453	
GO Biological Process	multi-organism metabolic process	79	5.984738e-9	9.968755359746836e-7	2.202434	67	0.01735751	162	0.0047688760230246915	1.713122	48	147	0.01341157	
GO Cellular Component	COPII vesicle coat	28	1.933452e-12	1.1932160914285714e-10	7.243526	22	0.005699482	60	0.02554295904	3.228577	8	13	0.002235261	
GO Cellular Component	endoplasmic reticulum exit site	30	1.370332e-11	7.89311232e-10	4.649008	30	0.007772021	55	0.012871306472727273	3.497625	8	12	0.002235261	
GO Cellular Component	ribosomal subunit	39	2.727912e-8	0.0000012086748553846153	2.075163	70	0.01813472	69	0.04310335721739131	1.474674	52	185	0.0145292	
GO Cellular Component	nuclear pore	49	6.047502e-7	0.000021326700930612247	2.26803	46	0.0119171	47	0.005993369463829787	1.95867	28	75	0.007823414	
GO Cellular Component	mitochondrial outer membrane translocase complex	71	0.00003510877	0.0008544782332394368	5.168629	10	0.002590674	48	0.0059074667999999995	3.815591	8	11	0.002235261	
GO Cellular Component	outer mitochondrial membrane protein complex	73	0.00004506898	0.0010668383210958904	4.554969	11	0.002849741	57	0.01630505027368421	3.147863	9	15	0.002514669	
GO Cellular Component	retromer, cargo-selective complex	92	0.0002128117	0.003997158886956522	14.13866	4	0.001036269	64	0.035589024	5.246438	4	4	0.001117631	
GO Molecular Function	aminoacyl-tRNA editing activity	7	1.291958e-11	7.792352394285715e-9	7.944788	19	0.00492228	77	0.048630218735064935	3.228577	8	13	0.002235261	
GO Molecular Function	deoxyribonucleotide binding	9	2.180466e-9	0.0000010228808279999999	18.96287	9	0.002331606	50	0.021195470168000004	5.246438	5	5	0.001397038	
GO Molecular Function	structural constituent of ribosome	13	1.146029e-8	0.0000037219495676923078	2.164493	67	0.01735751	35	0.012272811171428573	1.651656	51	162	0.01424979	
GO Molecular Function	protein transporter activity	15	5.456311e-8	0.000015357696694666668	2.244993	56	0.01450777	70	0.037938988502857145	1.748813	32	96	0.008941045	
GO Molecular Function	protein transmembrane transporter activity	133	0.0009274377	0.029440917063157896	2.840646	13	0.003367876	69	0.03713179245217391	2.914688	10	18	0.002794077	
Human Phenotype	Lactic acidosis	3	8.310435e-9	0.000018485177585	2.127996	71	0.01839378	28	0.042538087114285715	1.684987	44	137	0.01229394	
Mouse Phenotype Single KO	abnormal oxidative phosphorylation	17	0.000001522915	0.0008203136855882353	2.853241	28	0.007253886	49	0.029755017428571427	2.360897	18	40	0.005029338	
Mouse Phenotype	abnormal amino acid metabolism	5	1.388773e-9	0.0000026556117306	10.02868	13	0.003367876	85	0.03148955843647059	4.496946	6	7	0.001676446	
Mouse Phenotype	abnormal oxidative phosphorylation	19	0.000001800287	0.0009059233687894738	2.525884	34	0.00880829	30	0.0016486959717000001	2.468912	24	51	0.006705784	
Mouse Phenotype	increased fibroblast apoptosis	32	0.00001217253	0.0036369237290625	2.410777	31	0.008031088	84	0.028831058914285713	2.186016	20	48	0.005588153