# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	107	1.231587e-48	1.51462180682243e-46	2.159087	456	0.01174319	578	0.00014136124049307958	1.212996	108	118	0.007622812	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	139	6.911259e-38	6.5428242576259e-36	2.15272	354	0.009116428	660	0.00047684726871212126	1.224472	85	92	0.005999435	
GO Biological Process	organelle transport along microtubule	141	8.978985e-38	8.37974919255319e-36	2.005254	419	0.01079035	749	0.0014386725915620827	1.244989	62	66	0.004376059	
GO Biological Process	intrinsic apoptotic signaling pathway in response to DNA damage	143	1.436582e-37	1.3219568208391606e-35	2.123967	362	0.009322449	693	0.0007914737843578645	1.248481	65	69	0.004587804	
GO Biological Process	cotranslational protein targeting to membrane	152	1.039946e-36	9.003058825e-35	2.09018	367	0.009451212	586	0.00015247838551706486	1.230646	91	98	0.006422925	
GO Biological Process	axonal transport	184	7.521913e-31	5.379394193858696e-29	2.284947	250	0.006438155	1091	0.018695996015582035	1.257346	37	39	0.002611519	
GO Biological Process	gene silencing by miRNA	224	1.697031e-27	9.969299521875001e-26	2.124887	260	0.006695681	558	0.00009626780096415772	1.325311	44	44	0.00310559	
GO Biological Process	axo-dendritic transport	235	7.118152e-27	3.985862219914894e-25	2.067118	271	0.00697896	1078	0.01850734005380334	1.238877	43	46	0.003035008	
GO Biological Process	cytoplasmic microtubule organization	283	8.208837e-24	3.816964172544169e-22	2.092769	231	0.005948855	1262	0.04681260029080824	1.228337	38	41	0.002682101	
GO Biological Process	positive regulation of viral transcription	342	9.455131e-21	3.6380137084502926e-19	2.07129	204	0.005253535	985	0.010199593001624364	1.262201	40	42	0.002823264	
GO Biological Process	response to arsenic-containing substance	460	2.208911e-17	6.318926054130435e-16	2.070817	168	0.00432644	860	0.004309768354883721	1.325311	29	29	0.002046866	
GO Biological Process	establishment of mitochondrion localization	488	8.439885e-17	2.275828826127049e-15	2.1895	142	0.003656872	1221	0.038434680028665034	1.325311	20	20	0.001411632	
GO Biological Process	cytoplasmic translation	530	1.176345e-15	2.9206648783018867e-14	2.103388	144	0.003708377	1181	0.03254146046909399	1.232847	40	43	0.002823264	
GO Biological Process	deoxyribonucleotide catabolic process	686	5.331054e-13	1.0226142796793002e-11	2.394728	88	0.002266231	1269	0.04902732312529551	1.325311	19	19	0.00134105	
GO Biological Process	deoxyribose phosphate catabolic process	769	7.244135e-12	1.2396043233420027e-10	2.263415	89	0.002291983	1221	0.038434680028665034	1.325311	20	20	0.001411632	
GO Biological Process	snRNA processing	1247	7.842697e-8	8.276026449318364e-7	2.073765	66	0.001699673	1084	0.01857727894649447	1.325311	23	23	0.001623377	
GO Cellular Component	axon cytoplasm	51	6.262869e-32	2.1220073788235297e-30	2.307404	254	0.006541166	195	0.010859549538461539	1.259045	38	40	0.002682101	
GO Cellular Component	nuclear ubiquitin ligase complex	103	4.12652e-18	6.92293840776699e-17	2.166851	158	0.004068914	230	0.041723146017391306	1.225912	37	40	0.002611519	
GO Cellular Component	telomerase holoenzyme complex	123	3.976208e-16	5.5860873365853656e-15	2.57214	98	0.002523757	205	0.017102589190243902	1.325311	22	22	0.001552795	
GO Molecular Function	snRNA binding	108	1.997795e-13	7.809898601851852e-12	2.133913	117	0.003013057	180	0.04593505507777777	1.255557	36	38	0.002540937	
Mouse Phenotype Single KO	abnormal cellular replicative senescence	48	6.642019e-30	1.2671034996458332e-27	2.071775	302	0.007777291	243	0.00003448335900205761	1.303222	59	60	0.004164314	
Mouse Phenotype Single KO	early cellular replicative senescence	80	1.592866e-25	1.82323424525e-23	2.046035	263	0.006772939	301	0.00023302030853488372	1.299824	51	52	0.003599661	
Mouse Phenotype Single KO	increased squamous cell carcinoma incidence	243	6.773719e-15	2.5525491721399175e-13	2.027363	149	0.00383714	529	0.011365550691871456	1.325311	26	26	0.001835121	
Mouse Phenotype Single KO	increased mammary adenocarcinoma incidence	361	4.370623e-12	1.1086369753739612e-10	2.323917	86	0.002214725	650	0.02858326557076923	1.325311	22	22	0.001552795	
Mouse Phenotype	increased embryonic neuroepithelium apoptosis	258	1.106919e-17	4.1020358755813953e-16	2.130482	160	0.004120419	828	0.01005245156594203	1.325311	25	25	0.00176454	
Mouse Phenotype	abnormal stapedial artery morphology	313	6.264596e-16	1.91360390913738e-14	2.114491	145	0.00373413	1042	0.03272288952495202	1.325311	20	20	0.001411632	
Mouse Phenotype	absent stapedial artery	325	1.277704e-15	3.7588085981538457e-14	2.113537	142	0.003656872	1110	0.04072464021081081	1.325311	19	19	0.00134105